ketoconazole has been researched along with thiazoles in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickneite, G; Schorlemmer, HU; Sedlacek, HH | 1 |
| Bujdáková, H; Klobusický, M; Múcková, M; Sidóová, E | 1 |
| Acosta, D; Rodriguez, RJ | 2 |
| Laurent, A; Miceli, JJ; Morse, T; Robarge, L; Smith, M | 1 |
| Baillie, TA; Dean, D; Doss, G; Elmore, C; Kassahun, K; Leung, K; McIntosh, I; Pearson, PG; Tang, W; Wang, R | 1 |
| Ichihara, S; Murasaki, C; Ohwada, J; Shimma, N; Umeda, I; Yamazaki, T | 1 |
| Giuliano, KA | 1 |
| Konopka, JB; Martin, SW | 1 |
| Awano, K; Dean, D; Hop, CE; Karanam, BV; Komuro, M; Liu, DQ; Satoh, H; Vincent, SH; Wallace, M | 1 |
| Kanamaru, H; Kitamura, A; Komuro, S; Mizuno, Y; Natsui, K; Yabuki, M | 1 |
| Cano, J; Gené, J; Gilgado, F; Guarro, J; Serena, C | 1 |
| Adibpour, N; Daneshtalab, M; Khalaj, A; Rezaee, S | 1 |
| Abdel-Moty, SG; Abou-Ghadir, OM; Hussein, MA; Kafafy, AH | 1 |
| Agrawal, S; Blackwood-Chirchir, A; Burris, H; Chiappori, AA; Dhillon, N; Hong, D; Johnson, FM; Kaul, S; Luo, FR; Rosen, L; Sy, O | 1 |
| Hochfeld, M; Meng, X; Potkin, SG; Preskorn, S | 1 |
| Keirns, J; Kerbusch, V; Kowalski, D; Krauwinkel, W; Lee, J; Marion, A; Meijer, J; Moy, S; Roy, M; Sawamoto, T; Takusagawa, S; van Gelderen, M | 1 |
| Chen, JZ; Coraggio, M; Hau, J; Imperio, J; Liu, L; Lubach, JW; Wong, H | 1 |
| Chen, XY; Gao, ZW; Meng, J; Zhong, DF; Zhou, X | 1 |
| Chiu, YY; Ereshefsky, L; Loebel, A; Poola, N; Preskorn, SH | 1 |
| Ahmed, SA; de Hoog, GS; Duncanson, F; Fahal, AH; Kloezen, W; van de Sande, WW; Zijlstra, EE | 1 |
| Matsushima, N; Mendell, J; Parasrampuria, DA; Shi, M; Truitt, K; Zahir, H | 1 |
| Burhenne, J; Foerster, KI; Haefeli, WE; Lehmann, ML; Mikus, G; Schaumaeker, M | 1 |
| Goosen, TC; Lin, J; Malhotra, B; Tse, S; Yamagami, H | 1 |
1 review(s) available for ketoconazole and thiazoles
| Article | Year |
|---|---|
Lurasidone drug-drug interaction studies: a comprehensive review.
Topics: Antipsychotic Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Drug Therapy, Combination; Humans; Isoindoles; Ketoconazole; Lithium Compounds; Lurasidone Hydrochloride; Rifampin; Thiazoles | 2014 |
6 trial(s) available for ketoconazole and thiazoles
| Article | Year |
|---|---|
The effects of ketoconazole on ziprasidone pharmacokinetics--a placebo-controlled crossover study in healthy volunteers.
Topics: Adolescent; Adult; Antifungal Agents; Antipsychotic Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Female; Humans; Ketoconazole; Male; Mixed Function Oxygenases; Piperazines; Thiazoles | 2000 |
Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dasatinib; Drug Administration Schedule; Drug Interactions; Electrocardiography; Female; Heart; Humans; Ketoconazole; Male; Middle Aged; Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Thiazoles | 2010 |
A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult | 2013 |
Role of cytochrome p450 isoenzymes 3A and 2D6 in the in vivo metabolism of mirabegron, a β3-adrenoceptor agonist.
Topics: Acetanilides; Adolescent; Adrenergic beta-3 Receptor Agonists; Adult; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Drug Interactions; Female; Half-Life; Humans; Ketoconazole; Male; Middle Aged; Rifampin; Thiazoles; Young Adult | 2013 |
Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine.
Topics: Administration, Oral; Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cyclosporine; Cytochrome P-450 CYP3A; Drug Administration Schedule; Drug Interactions; Erythromycin; Factor Xa Inhibitors; Healthy Volunteers; Humans; Ketoconazole; Metabolic Clearance Rate; Middle Aged; Pyridines; Substrate Specificity; Thiazoles; Young Adult | 2016 |
Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug-Drug Interactions with Potential Perpetrator Drugs.
Topics: Administration, Oral; Adolescent; Adult; Atrial Fibrillation; Case-Control Studies; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Factor Xa Inhibitors; Female; Humans; Ketoconazole; Male; Middle Aged; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Tandem Mass Spectrometry; Thiazoles; Young Adult | 2019 |
17 other study(ies) available for ketoconazole and thiazoles
| Article | Year |
|---|---|
Influence of the immunostimulating substance tiprotimod on Candida albicans infection in relation to activation of macrophages.
Topics: Adjuvants, Immunologic; Animals; Candidiasis; Dextran Sulfate; Dextrans; Drug Therapy, Combination; Escherichia coli; Female; Free Radicals; Ketoconazole; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Nude; Superoxides; Thiazoles | 1989 |
Efficacy of 6-amino-2-n-pentylthiobenzothiazole on Trichophyton in vitro and in vivo.
Topics: Animals; Antifungal Agents; Benzothiazoles; Clotrimazole; Guinea Pigs; Ketoconazole; Microbial Sensitivity Tests; Thiazoles; Tinea; Trichophyton | 1995 |
Comparison of ketoconazole- and fluconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes.
Topics: Analysis of Variance; Animals; Cell Membrane Permeability; Cells, Cultured; Fluconazole; Ketoconazole; L-Lactate Dehydrogenase; Liver; Lysosomes; Mitochondria, Liver; Neutral Red; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1995 |
N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes.
Topics: Animals; Antifungal Agents; Cell Membrane; Cells, Cultured; Coloring Agents; Female; Ketoconazole; L-Lactate Dehydrogenase; Liver; Male; Mitochondria; Oxidation-Reduction; Oxygenases; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1997 |
Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.
Topics: Animals; Bile; Biotransformation; Catalysis; Chromans; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glutathione; Humans; Hypoglycemic Agents; Isoenzymes; Ketoconazole; Kinetics; Mass Spectrometry; Microsomes, Liver; NADP; Rats; Steroid Hydroxylases; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals.
Topics: Animals; Antifungal Agents; Aspergillus fumigatus; Azoles; Candida albicans; Candidiasis; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Prodrugs; Rats; Solubility; Thiazoles; Triazoles | 2002 |
High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole.
Topics: Animals; Antifungal Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Size; Cyclopropanes; Drug Interactions; Humans; Ketoconazole; Microtubules; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Thiazoles; Vinblastine | 2003 |
Lipid raft polarization contributes to hyphal growth in Candida albicans.
Topics: Antifungal Agents; Bridged Bicyclo Compounds, Heterocyclic; Candida albicans; Cell Membrane; Cell Polarity; Ergosterol; Fatty Acids, Monounsaturated; Filipin; Hyphae; Ketoconazole; Membrane Microdomains; Sphingolipids; Sterols; Thiazoles; Thiazolidines | 2004 |
In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. I. Role of cytochrome P450, methyltransferases, flavi
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzylamines; Carbon Radioisotopes; Cytosol; Dogs; Drug Evaluation, Preclinical; Esterases; Hepatocytes; Humans; Ketoconazole; Macaca mulatta; Methyltransferases; Microsomes, Liver; Mixed Function Oxygenases; NADP; PPAR alpha; PPAR gamma; Rats; S-Adenosylmethionine; Sulfhydryl Compounds; Sulfoxides; Temperature; Thiazoles; Thiazolidinediones | 2004 |
Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
Topics: Antibodies, Monoclonal; Antipsychotic Agents; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Isoindoles; Ketoconazole; Male; Microsomes, Liver; Models, Chemical; Quercetin; Quinidine; Thiazoles | 2005 |
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.
Topics: Amphotericin B; Antifungal Agents; Candida; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Naphthalenes; Peptides, Cyclic; Pseudallescheria; Pyrimidines; Quality Control; Quinazolines; Scedosporium; Terbinafine; Thiazoles; Triazoles; Voriconazole | 2006 |
In vitro antifungal activity of 2-(4-substituted phenyl)-3(2H)-isothiazolones.
Topics: Antifungal Agents; Ascomycota; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Thiazoles | 2007 |
Synthesis and biological activities of new substituted thiazoline-quinoline derivatives.
Topics: Acetophenones; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Edema; Fluoroquinolones; Fungi; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Indomethacin; Ketoconazole; Lethal Dose 50; Male; Mice; Quinolines; Rats; Stomach Ulcer; Thiazoles; Toxicity Tests, Acute | 2009 |
Investigation of the rat model for preclinical evaluation of pH-dependent oral absorption in humans.
Topics: Administration, Oral; Animals; Dasatinib; Famotidine; Humans; Hydrogen-Ion Concentration; Ketoconazole; Male; Mefenamic Acid; Pentagastrin; Pyrimidines; Rats; Rats, Sprague-Dawley; Solubility; Thiazoles | 2013 |
Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti-hepatitis B virus compound, in dogs.
Topics: Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Dogs; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Humans; Ketoconazole; Male; Microsomes, Liver; Pyrimidines; Rifampin; Species Specificity; Tandem Mass Spectrometry; Thiazoles | 2013 |
Madurella mycetomatis is highly susceptible to ravuconazole.
Topics: Antifungal Agents; Itraconazole; Ketoconazole; Madurella; Microbial Sensitivity Tests; Thiazoles; Triazoles | 2014 |
Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug-Drug Interaction for Fesoterodine When Coadministered With Mirabegron.
Topics: Acetanilides; Adult; Benzhydryl Compounds; Cresols; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ketoconazole; Male; Middle Aged; Rifampin; Thiazoles; Urinary Bladder, Overactive | 2019 |