ketoconazole and taurocholic acid

ketoconazole has been researched along with taurocholic acid in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cvetkovic, M; Kim, RB; Leake, B; Nadeau, J; Roden, MM; Walubo, A; Wilkinson, GR1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Breäs, R; Crommelin, DJ; Poelma, FG; Tukker, JJ1
Breäs, R; Poelma, FG; Tukker, JJ1
Huijsmans, CM; Kempen, HJ; Kuipers, F; Princen, HM; Vonk, RJ1
Azer, SA; Kukongviriyapan, V; Stacey, NH1
Badolo, L; Jørgensen, L; Lund, S; Schousboe, A; Van Beek, J1
Ali, I; Brouwer, KLR; Khalid, S; Stieger, B1

Other Studies

9 other study(ies) available for ketoconazole and taurocholic acid

ArticleYear
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Bile Acids and Salts; Biological Transport, Active; Carrier Proteins; Cells, Cultured; HeLa Cells; Humans; Kinetics; Liver; Nicotine; Organic Anion Transporters, Sodium-Dependent; Plasmids; RNA, Messenger; Salicylates; Symporters; Vaccinia virus; Valproic Acid

1999
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Intestinal absorption of drugs. The influence of mixed micelles on on the disappearance kinetics of drugs from the small intestine of the rat.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:5

    Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Dantrolene; Griseofulvin; Intestinal Absorption; Intestine, Small; Ketoconazole; Kinetics; Lysophosphatidylcholines; Micelles; Models, Biological; Mucus; Rats; Solubility; Swine; Taurocholic Acid; Theophylline

1991
Intestinal absorption of drugs. III. The influence of taurocholate on the disappearance kinetics of hydrophilic and lipophilic drugs from the small intestine of the rat.
    Pharmaceutical research, 1990, Volume: 7, Issue:4

    Topics: Acetaminophen; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Griseofulvin; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Ketoconazole; Models, Biological; Perfusion; Pharmacokinetics; Rats; Solubility; Taurocholic Acid; Theophylline

1990
Ketoconazole blocks bile acid synthesis in hepatocyte monolayer cultures and in vivo in rat by inhibiting cholesterol 7 alpha-hydroxylase.
    The Journal of clinical investigation, 1986, Volume: 78, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Cells, Cultured; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Ketoconazole; Liver; Male; Microsomes, Liver; Rats; Steroid Hydroxylases; Taurocholic Acid

1986
Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Animals; Bile Acids and Salts; Biological Transport; Cell Survival; Cholic Acid; Cholic Acids; In Vitro Techniques; Ketoconazole; Liver; Male; Ouabain; Rats; Rats, Sprague-Dawley; Taurocholic Acid

1995
Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 30, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Cells, Cultured; Cryopreservation; Female; Hepatocytes; Immunohistochemistry; Ketoconazole; Male; Organic Anion Transport Protein 1; Probenecid; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurocholic Acid; Time Factors; Vinblastine

2007
Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications.
    Molecular pharmaceutics, 2019, 03-04, Volume: 16, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; Baculoviridae; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Dipyridamole; Erythromycin; Glycocholic Acid; Ketoconazole; Kinetics; Membrane Transport Proteins; Polymorphism, Single Nucleotide; Sf9 Cells; Signal Transduction; Spodoptera; Taurocholic Acid; Transport Vesicles

2019