ketoconazole and sulfamethoxazole

ketoconazole has been researched along with sulfamethoxazole in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199010 (38.46)18.7374
1990's3 (11.54)18.2507
2000's2 (7.69)29.6817
2010's10 (38.46)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Hunziker, UA; Jendis, JB; Nadal, D; Schüpbach, J; Seger, RA; Tomasik, Z; Wetzel, JC1
Fischer, A; Griscelli, C; Mouy, R; Seger, R; Vilmer, E1
Ramírez-Ronda, CH; Santana, JL1
de Pauw, BE; Haanen, C; Stalpers, LJ; Verhagen, C1
Bremer, HJ; Koletzko, B; Wendel, U1
Bircher, A; Furger, F; Lang, W; Lüthy, R; Maurer, R; Siegenthaler, W; Vogt, M1
Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T1
Beggs, WH1
Cruciani, M; Klastersky, J; Meunier-Carpentier, F1
Berman, JD; Lee, LS1
Fraser-Smith, EB; Freitas, VR; Matthews, TR1
Kalhorn, TF; Kharasch, ED; Mitra, AK; Slattery, JT; Thummel, KE; Unadkat, JD1
Gill, HJ; Madden, S; Maggs, JL; Park, BK; Pirmohamed, M1
Chitescu, CL; Nicolau, AI; Stolker, AA1
Block, SL1
Niemissalo, SM; Pihlaja, TLM; Sikanen, TM1

Trials

4 trial(s) available for ketoconazole and sulfamethoxazole

ArticleYear
Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two.
    Archives of internal medicine, 1984, Volume: 144, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Drug Combinations; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Humans; Ketoconazole; Leukemia; Middle Aged; Mycoses; Pneumonia; Sepsis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1984
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1

    Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Middle Aged; Mycoses; Neoplasms; Neutropenia; Piperazines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1983
Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:3

    Topics: Adult; Antifungal Agents; Cimetidine; Fluconazole; Histamine H2 Antagonists; Humans; Ketoconazole; Male; Microsomes, Liver; Reference Values; Sulfamethoxazole

1996
The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:3

    Topics: Adult; Anti-Infective Agents; Antifungal Agents; Fluconazole; Humans; Hydroxylation; Ketoconazole; Male; Middle Aged; Sulfamethoxazole

1996

Other Studies

22 other study(ies) available for ketoconazole and sulfamethoxazole

ArticleYear
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Stable human immunodeficiency virus encephalopathy in two infants receiving early intravenous gammaglobulin plus antimicrobial prophylaxis.
    European journal of pediatrics, 1989, Volume: 148, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Drug Combinations; Drug Therapy, Combination; HIV Antibodies; HIV Antigens; Humans; Immunoglobulin G; Immunoglobulins, Intravenous; Infant; Infant, Newborn; Ketoconazole; Male; Neurologic Examination; Opportunistic Infections; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Incidence, severity, and prevention of infections in chronic granulomatous disease.
    The Journal of pediatrics, 1989, Volume: 114, Issue:4 Pt 1

    Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Genetic Linkage; Granulomatous Disease, Chronic; Humans; Infant; Infant, Newborn; Ketoconazole; Mycoses; Paris; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; X Chromosome

1989
[The pregnant woman infected with the human immunodeficiency virus: recommendations for her management].
    Boletin de la Asociacion Medica de Puerto Rico, 1988, Volume: 80, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Candidiasis; Cytomegalovirus Infections; Female; Humans; Ketoconazole; Opportunistic Infections; Pneumonia, Pneumocystis; Pregnancy; Pregnancy Complications, Infectious; Sulfamethoxazole; Toxoplasmosis; Trimethoprim

1988
Drug-induced skin reactions in patients with acute non-lymphocytic leukaemia.
    European journal of haematology, 1987, Volume: 38, Issue:3

    Topics: Acute Disease; Adult; Allopurinol; Cephalosporins; Drug Combinations; Drug Eruptions; Female; Humans; Ketoconazole; Leukemia; Male; Miconazole; Penicillins; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1987
Lithium for treatment of neutropenia in glycogen storage disease type Ib.
    The Journal of pediatrics, 1986, Volume: 109, Issue:5

    Topics: Agranulocytosis; Chlorides; Drug Combinations; Drug Therapy, Combination; Female; Glycogen Storage Disease Type I; Hematopoiesis; Humans; Ketoconazole; Leukocyte Count; Lithium; Lithium Chloride; Neutropenia; Skin Diseases, Infectious; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
[Heterosexual transmission of the acquired immunodeficiency syndrome (AIDS)].
    Deutsche medizinische Wochenschrift (1946), 1985, Sep-27, Volume: 110, Issue:39

    Topics: Acquired Immunodeficiency Syndrome; Adult; Bone Marrow Examination; Bronchi; Candidiasis; Cerebral Infarction; Child, Preschool; Coitus; Demyelinating Diseases; Drug Combinations; Female; Humans; Ketoconazole; Male; Pneumocystis; Pneumonia; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Combined activity of ketoconazole and sulphamethoxazole against Candida albicans.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10, Issue:6

    Topics: Antifungal Agents; Candida albicans; Drug Synergism; Imidazoles; Ketoconazole; Piperazines; Sulfamethoxazole

1982
Activity of oral drugs against Leishmania tropica in human macrophages in vitro.
    The American journal of tropical medicine and hygiene, 1983, Volume: 32, Issue:5

    Topics: Antiprotozoal Agents; Cells, Cultured; Drug Interactions; Humans; Isoniazid; Ketoconazole; Leishmania; Macrophages; Metronidazole; Nitrofurans; Phenothiazines; Quinacrine; Rifampin; Sulfamethoxazole; Trimethoprim

1983
Efficacy of ganciclovir in combination with other antimicrobial agents against cytomegalovirus in vitro and in vivo.
    Antiviral research, 1993, Volume: 20, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus Infections; Dapsone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Ganciclovir; Humans; Ketoconazole; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Species Specificity; Sulfamethoxazole; Survival Analysis; Trimethoprim; Viral Plaque Assay

1993
Dofetilide for atrial fibrillation.
    The Medical letter on drugs and therapeutics, 2000, May-15, Volume: 42, Issue:1078

    Topics: Anti-Arrhythmia Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Anti-Ulcer Agents; Antifungal Agents; Atrial Fibrillation; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ketoconazole; Phenethylamines; Potassium Channel Blockers; Sulfamethoxazole; Sulfonamides; Torsades de Pointes; Trimethoprim

2000
Uptake of oxytetracycline, sulfamethoxazole and ketoconazole from fertilised soils by plants.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2013, Volume: 30, Issue:6

    Topics: Chromatography, Liquid; Fertilizers; Ketoconazole; Oxytetracycline; Plants; Soil Pollutants; Sulfamethoxazole; Tandem Mass Spectrometry

2013
Tricky triggers of intertrigo.
    Pediatric annals, 2014, Volume: 43, Issue:5

    Topics: Acyclovir; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antiviral Agents; Candidiasis; Child, Preschool; Clindamycin; Female; Herpes Simplex; Humans; Infant; Infant, Newborn; Intertrigo; Ketoconazole; Male; Staphylococcal Infections; Sulfamethoxazole; Trimethoprim

2014
Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro.
    Environmental toxicology and chemistry, 2022, Volume: 41, Issue:3

    Topics: Animals; Ciprofloxacin; Clotrimazole; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ketoconazole; Liver; Microsomes, Liver; Oncorhynchus mykiss; Sulfamethoxazole

2022