Compounds > ketoconazole

ketoconazole and su 11248

ketoconazole has been researched along with su 11248 in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	8 (72.73)	24.3611
2020's	3 (27.27)	2.80

Authors

Authors	Studies
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Calvet, CM; Cameron, MD; Choi, JY; Gunatilleke, SS; McKerrow, JH; Podust, LM; Roush, WR; Ruiz, C	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW	1
Chee, EL; Fernandez-Lastra, C; Lim, AY; Modamio, P; Segarra, I	1
Abouda, AA; Amaya, GM; Bourgeois, DS; Daniels, RN; Durandis, R; Jackson, KD; Mohamud, M; Perkins, JA; Starks, SA; Wines, KJ	1
Peiró, I; Simó-Servat, A; Villabona, C	1
Chen, RJ; Cheng, C; Cui, X; Huang, CK; Sun, W; Wang, J; Wang, Y; Wang, Z	1
Abdel-Mageed, AB; Barata, PC; Boulares, AH; Datta, A; Greenberg, JW; Kim, H; Krane, LS; Moustafa, AA	1

Reviews

2 review(s) available for ketoconazole and su 11248

Article	Year
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

9 other study(ies) available for ketoconazole and su 11248

Article	Year
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Rational development of 4-aminopyridyl-based inhibitors targeting Trypanosoma cruzi CYP51 as anti-chagas agents. Journal of medicinal chemistry, 2013, Oct-10, Volume: 56, Issue:19 Topics: 14-alpha Demethylase Inhibitors; Aminopyridines; Animals; Crystallography, X-Ray; Humans; Indoles; Mice; Microsomes, Liver; Molecular Docking Simulation; Rats; Stereoisomerism; Sterol 14-Demethylase; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2013
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1). Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries	2017
Sunitinib tissue distribution changes after coadministration with ketoconazole in mice. European journal of drug metabolism and pharmacokinetics, 2016, Volume: 41, Issue:3 Topics: Animals; Antifungal Agents; Area Under Curve; Drug Interactions; Female; Half-Life; Indoles; Ketoconazole; Mice; Mice, Inbred ICR; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Tissue Distribution	2016
Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib. Chemical research in toxicology, 2018, 07-16, Volume: 31, Issue:7 Topics: Biocatalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Enzyme Inhibitors; Glutathione; Humans; Ketoconazole; Kinetics; Microsomes, Liver; Quinones; Recombinant Proteins; Spectrophotometry, Ultraviolet; Sunitinib; Tandem Mass Spectrometry	2018
Corticotropin secreting pancreatic neuroendocrine tumour, a therapeutic management challenge. A presentation of 2 cases. Endocrinologia, diabetes y nutricion, 2019, Volume: 66, Issue:3 Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Chromogranins; Combined Modality Therapy; Embolization, Therapeutic; Everolimus; Female; Fludrocortisone; Humans; Hydrocortisone; Ketoconazole; Liver Neoplasms; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Peptides, Cyclic; Phenylurea Compounds; Quinolines; Somatostatin; Spironolactone; Splenectomy; Sunitinib	2019
Effects of CYP3A inhibitors ketoconazole, voriconazole, and itraconazole on the pharmacokinetics of sunitinib and its main metabolite in rats. Chemico-biological interactions, 2021, Apr-01, Volume: 338 Topics: Administration, Oral; Animals; Cytochrome P-450 CYP3A Inhibitors; Itraconazole; Ketoconazole; Male; Rats, Sprague-Dawley; Sunitinib; Voriconazole	2021
Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma. Scientific reports, 2021, 05-13, Volume: 11, Issue:1 Topics: Adult; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Repositioning; Drug Resistance, Neoplasm; Drug Therapy, Combination; Exosomes; Female; Humans; Ketoconazole; Kidney Neoplasms; Male; Middle Aged; Primary Cell Culture; Signal Transduction; Sunitinib	2021