ketoconazole has been researched along with sirolimus in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chai, A; Chan, AO; O'Mahony, D; Ramtoola, Z; Silverman, JA; Tran-Tau, P; Wacher, VJ; Wong, S; Yu, XQ | 1 |
| Jacob, CK; John, GT; Manivannan, J; Thomas, PP | 1 |
| Beyer, D; Bizot, MN; Jiang, Q; Kovarik, JM; Schmouder, RL; Shenouda, M | 1 |
| Boni, JP; Burns, J; Hug, B; Leister, C | 1 |
| Agrawal, N; Breidinger, S; Iwamoto, M; Johnson-Levonas, A; Kraft, WK; Marsilio, S; McCrea, J; Murphy, G; Orford, K; Palcza, J; Panebianco, D; Stroh, M; Trucksis, M; Wagner, JA | 1 |
| Cohen, EE; Eaton, KN; Fleming, GF; Fox-Kay, K; Gajewski, TF; Hartford, C; House, L; Kocherginsky, M; Maitland, ML; Moshier, K; Nallari, A; Ramirez, J; Ratain, MJ; Undevia, SD; Wu, K; Zha, Y | 1 |
| Andersson, BS; Hassan, M; Valdez, BC | 1 |
| Atsriku, C; Li, Y; Liu, H; Narayanan, R; Nissel, J; Surapaneni, S; Tong, Z; Wang, X | 1 |
| Jiang, L; Pan, H | 1 |
| Alterovitz, G; Bai, Y; Bi, Y; Chen, H; Chen, X; Dai, H; Durrani, TS; Farooqi, A; Fatibello-Filho, O; Gao, L; Gong, L; Greenwell, K; Guo, YX; Han, D; He, L; Howells, L; Huang, H; Huang, S; Jester, N; Jiang, PP; Kang, P; Kang, Y; Kraemer, R; Lan, X; Lawton, S; Li, C; Li, H; Liu, G; Liu, J; Liu, P; Matthys, H; Meng, Y; Moraes, FC; Muller, I; Pan, C; Qu, L; Roberts, A; Santer, M; Silva, LP; Silva, TA; Sivyer, K; Smith, HJ; Song, F; Steele, M; Sun, N; Teasdale, E; Tong, Y; Wang, D; Wang, L; Wang, Q; Wang, S; Xiao, M; Xin, D; Xu, C; Xu, J; Yang, XL; Zhang, B; Zhang, D; Zhang, J; Zhang, L; Zhang, Q; Zhong, L; Zhu, H | 1 |
3 review(s) available for ketoconazole and sirolimus
| Article | Year |
|---|---|
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Antifungal Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Azoles; Candida albicans; Carbon Dioxide; Child; Chitosan; Chronic Periodontitis; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Environmental Monitoring; Female; Fluorides; Functional Residual Capacity; Gene Deletion; Genotype; Goats; Gold; Groundwater; Haplotypes; Humans; Infant; Insulin-Like Growth Factor II; Ketoconazole; Linkage Disequilibrium; Litter Size; Liver Diseases; Male; Metal Nanoparticles; Middle Aged; Nanocomposites; Pakistan; Peptides; Periodontal Attachment Loss; Periodontal Index; Plethysmography, Whole Body; Pneumoperitoneum, Artificial; Reference Standards; Remifentanil; Respiratory Function Tests; Respiratory Mechanics; Retrospective Studies; RNA-Binding Proteins; Sevoflurane; Sirolimus; Soot; Tidal Volume; Tumor Necrosis Factor Inhibitors; Water Pollutants, Chemical | 2021 |
4 trial(s) available for ketoconazole and sirolimus
| Article | Year |
|---|---|
Blood concentrations of everolimus are markedly increased by ketoconazole.
Topics: Adult; Antifungal Agents; Area Under Curve; Cross-Over Studies; Drug Synergism; Everolimus; Female; Half-Life; Humans; Immunosuppressive Agents; Ketoconazole; Male; Middle Aged; Sirolimus | 2005 |
The effect of multiple doses of rifampin and ketoconazole on the single-dose pharmacokinetics of ridaforolimus.
Topics: Adult; Antineoplastic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Drug Interactions; Half-Life; Humans; Ketoconazole; Male; Middle Aged; Rifampin; Sirolimus; Young Adult | 2012 |
Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Citrus paradisi; Female; Humans; Hyperglycemia; Hyperlipidemias; Ketoconazole; Lymphopenia; Male; Middle Aged; Neoplasm Staging; Neoplasms; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; TOR Serine-Threonine Kinases | 2012 |
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Antifungal Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Azoles; Candida albicans; Carbon Dioxide; Child; Chitosan; Chronic Periodontitis; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Environmental Monitoring; Female; Fluorides; Functional Residual Capacity; Gene Deletion; Genotype; Goats; Gold; Groundwater; Haplotypes; Humans; Infant; Insulin-Like Growth Factor II; Ketoconazole; Linkage Disequilibrium; Litter Size; Liver Diseases; Male; Metal Nanoparticles; Middle Aged; Nanocomposites; Pakistan; Peptides; Periodontal Attachment Loss; Periodontal Index; Plethysmography, Whole Body; Pneumoperitoneum, Artificial; Reference Standards; Remifentanil; Respiratory Function Tests; Respiratory Mechanics; Retrospective Studies; RNA-Binding Proteins; Sevoflurane; Sirolimus; Soot; Tidal Volume; Tumor Necrosis Factor Inhibitors; Water Pollutants, Chemical | 2021 |
10 other study(ies) available for ketoconazole and sirolimus
| Article | Year |
|---|---|
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Humans; Intestinal Absorption; Ketoconazole; Kinetics; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Sirolimus; Tumor Cells, Cultured; Vitamin E | 2002 |
Sirolimus and ketoconazole co-prescription in renal transplant recipients.
Topics: Adult; Antifungal Agents; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Ketoconazole; Kidney Transplantation; Male; Middle Aged; Salvage Therapy; Sirolimus; Treatment Outcome | 2004 |
Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus.
Topics: Adolescent; Adult; Antineoplastic Agents; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Ketoconazole; Male; Middle Aged; Sirolimus | 2008 |
Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions.
Topics: Antineoplastic Agents, Alkylating; Biological Transport; Busulfan; Cell Line, Tumor; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Interactions; Ethacrynic Acid; Everolimus; Flow Cytometry; Fluoresceins; Humans; Ketoconazole; Melphalan; Multidrug Resistance-Associated Proteins; Reproducibility of Results; Sirolimus | 2017 |
Assessment of drug-drug interaction potential and PBPK modeling of CC-223, a potent inhibitor of the mammalian target of rapamycin kinase.
Topics: Animals; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Ketoconazole; Membrane Transport Proteins; Microsomes, Liver; Prospective Studies; Pyrazines; Sirolimus; TOR Serine-Threonine Kinases | 2019 |
Functions of CaPhm7 in the regulation of ion homeostasis, drug tolerance, filamentation and virulence in Candida albicans.
Topics: Animals; Candida albicans; Candidiasis; Disease Models, Animal; Drug Resistance, Fungal; Fungal Proteins; Homeostasis; Hyphae; Ketoconazole; Mice; Sirolimus; Sodium Dodecyl Sulfate; Transient Receptor Potential Channels; Virulence; Zinc | 2018 |