ketoconazole and quinone

ketoconazole has been researched along with quinone in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (60.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	1 (20.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Bertilsson, L; Ericsson, O; Gustafsson, LL; Hellgren, U; Mirghani, RA	1
Ishihara, Y; Shiba, D; Shimamoto, N	1
Ding, L; Li, X; Ma, S; Pan, H; Shi, F; Zhao, P	1
Hu, Z; Peng, Y; Shi, J; Su, M; Sun, C; Zhao, Y; Zheng, J	1

Trials

1 trial(s) available for ketoconazole and quinone

Article	Year
Metabolism and elimination of quinine in healthy volunteers. European journal of clinical pharmacology, 2003, Volume: 59, Issue:5-6 Topics: Antimalarials; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Ketoconazole; Mixed Function Oxygenases; Quinidine; Quinine; Quinones; Time Factors	2003

Article

Year

Metabolism and elimination of quinine in healthy volunteers.

European journal of clinical pharmacology, 2003, Volume: 59, Issue:5-6

Topics: Antimalarials; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Ketoconazole; Mixed Function Oxygenases; Quinidine; Quinine; Quinones; Time Factors

2003

Other Studies

4 other study(ies) available for ketoconazole and quinone

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition. Toxicology and applied pharmacology, 2006, Jul-15, Volume: 214, Issue:2 Topics: Animals; Antioxidants; Benzoquinones; Catecholamines; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione Disulfide; Hepatocytes; Imidazolines; Iron Chelating Agents; Ketoconazole; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Metyrapone; Molecular Structure; NADP; Naphthoquinones; Oxidative Stress; Proadifen; Rats; Rats, Wistar; Superoxides; Thiobarbituric Acid Reactive Substances	2006
Cytotoxicity of luteolin in primary rat hepatocytes: the role of CYP3A-mediated ortho-benzoquinone metabolite formation and glutathione depletion. Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:11 Topics: Animals; Apoptosis; Benzoquinones; Buthionine Sulfoximine; Cell Line; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Glutathione; Hepatocytes; Ketoconazole; Luteolin; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2015
Evidence for Metabolic Activation of Omeprazole In Vitro and In Vivo. Chemical research in toxicology, 2022, 09-19, Volume: 35, Issue:9 Topics: Acetylcysteine; Activation, Metabolic; Animals; Benzoquinones; Cytochrome P-450 CYP3A; Glutathione; Humans; Imines; Ketoconazole; Microsomes, Liver; Omeprazole; Proton Pump Inhibitors; Rats	2022