ketoconazole has been researched along with quinone methide in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Wang, Y; Zheng, J; Zhong, D | 1 |
| Jiang, H; Ma, L; Shen, Q; Tian, Y; Wang, L; Yu, L; Zeng, S; Zhou, H; Zhou, Q; Zuo, M | 1 |
| Li, W; Liu, M; Peng, Y; Wang, A; Wang, Y; Zhao, G; Zhao, Q; Zheng, J | 1 |
3 other study(ies) available for ketoconazole and quinone methide
| Article | Year |
|---|---|
Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile.
Topics: Administration, Oral; Animals; Benzylisoquinolines; Bile; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Glutathione; Humans; Indolequinones; Ketoconazole; Microsomes, Liver; Rats; Spectrometry, Mass, Electrospray Ionization; Tetrahydroisoquinolines | 2009 |
Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Benzylisoquinolines; Buthionine Sulfoximine; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Glutathione; Hep G2 Cells; Humans; Indolequinones; Ketoconazole; Kinetics; Madin Darby Canine Kidney Cells; Microsomes, Liver; Troleandomycin | 2014 |
In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A.
Topics: Activation, Metabolic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 CYP3A; Glutathione; Humans; Ketoconazole; Mice; Microsomes, Liver; Rats; Tolterodine Tartrate | 2023 |