ketoconazole and quetiapine fumarate

ketoconazole has been researched along with quetiapine fumarate in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Grimm, SW; Reele, SB; Richtand, NM; Stams, KR; Winter, HR	1
Hasselstrøm, J; Linnet, K	1
Hochfeld, M; Meng, X; Potkin, SG; Preskorn, S	1

Trials

2 trial(s) available for ketoconazole and quetiapine fumarate

Article	Year
Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. British journal of clinical pharmacology, 2006, Volume: 61, Issue:1 Topics: Administration, Oral; Adult; Antipsychotic Agents; Carbamazepine; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Male; Mental Disorders; Microsomes, Liver; Middle Aged; Quetiapine Fumarate	2006
A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:1 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult	2013

Article

Year

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics.

British journal of clinical pharmacology, 2006, Volume: 61, Issue:1

Topics: Administration, Oral; Adult; Antipsychotic Agents; Carbamazepine; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Male; Mental Disorders; Microsomes, Liver; Middle Aged; Quetiapine Fumarate

2006

A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.

Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:1

Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult

2013

Other Studies

1 other study(ies) available for ketoconazole and quetiapine fumarate

Article	Year
In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions. Drug metabolism and drug interactions, 2006, Volume: 21, Issue:3-4 Topics: Antipsychotic Agents; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Dibenzothiazepines; DNA, Circular; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Mass Spectrometry; Microsomes, Liver; Quetiapine Fumarate; Quinidine	2006

Article

Year

In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions.

Drug metabolism and drug interactions, 2006, Volume: 21, Issue:3-4

Topics: Antipsychotic Agents; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Dibenzothiazepines; DNA, Circular; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Mass Spectrometry; Microsomes, Liver; Quetiapine Fumarate; Quinidine

2006