ketoconazole has been researched along with quercetin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (45.45) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Caligari, S; Callegari, E; De Toma, C; Dilernia, R; Frigerio, F; Graziani, D; Longhi, M; Menegon, S; Pinzi, L; Pirona, L; Rastelli, G; Riva, C; Tazzari, V; Valsecchi, AE; Vistoli, G | 1 |
| Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C | 1 |
| Chen, Y; Dong, R; Hou, S; Huang, J; Li, H; Liu, C; Liu, X; Lu, T; Tang, W; Wang, X; Xu, J; Zhang, T; Zhang, Y | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Muftuoglu, Y; Mustata, G | 1 |
| Barison, A; Cabral, EC; Campos, FR; Costa, EV; Eberlin, MN; Maia, BH; Pinheiro, ML; Salvador, MJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Li, H; Martásek, P; Poulos, TL; Qin, Y; Roman, LJ; Silverman, RB; Wang, HY | 1 |
| Alvinerie, M; Dupuy, J; Larrieu, G; Lespine, A; Sutra, JF | 1 |
| Kanamaru, H; Kitamura, A; Komuro, S; Mizuno, Y; Natsui, K; Yabuki, M | 1 |
| Aubert, C; Bun, H; Bun, SS; Ciccolini, J; Fanciullino, R; Giacometti, S | 1 |
| Courtney, P; Grime, K; O'Donnell, CJ; Riley, RJ; Slee, D | 1 |
| Ask, B; Eliasson, E; Inotsume, N; Rane, A; Toda, T | 1 |
| Gray, BP; Hillyer, LL; Hudson, SC; Scarth, JP; Spencer, HA; Teale, P | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
1 trial(s) available for ketoconazole and quercetin
| Article | Year |
|---|---|
Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Antifungal Agents; Area Under Curve; Biological Availability; Cells, Cultured; Drug Interactions; Hepatocytes; Ivermectin; Ketoconazole; Macrolides; Male; Quercetin; Rats; Rats, Sprague-Dawley; Sheep, Domestic | 2003 |
21 other study(ies) available for ketoconazole and quercetin
| Article | Year |
|---|---|
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5.
Topics: Allosteric Regulation; Amides; Animals; Biological Availability; Carbamates; CHO Cells; Cricetulus; Dogs; Excitatory Amino Acid Agents; Humans; Ligands; Rats; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship; Sulfonamides; Urea | 2019 |
Development of Robust 17(
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar | 2019 |
Discovery of
Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Catalytic Domain; Cell Line, Tumor; Cyclin-Dependent Kinase 9; Half-Life; Humans; Mice; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2021 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis | 2006 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents.
Topics: Alkaloids; Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Aporphines; Brazil; Candida; Escherichia coli; Guatteria; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plants, Medicinal; Pseudomonas aeruginosa; Staphylococcus | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.
Topics: Aminopyridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Molecular Structure; Nitric Oxide Synthase Type I; Structure-Activity Relationship | 2016 |
Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
Topics: Antibodies, Monoclonal; Antipsychotic Agents; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Isoindoles; Ketoconazole; Male; Microsomes, Liver; Models, Chemical; Quercetin; Quinidine; Thiazoles | 2005 |
Effect of several compounds on biliary excretion of paclitaxel and its metabolites in guinea-pigs.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Bile; Biotransformation; Dexamethasone; Dogs; Drug Interactions; Glucocorticoids; Guinea Pigs; Humans; Ketoconazole; Liver; Macaca fascicularis; Male; Mice; Microsomes, Liver; Models, Animal; Paclitaxel; Quercetin; Rabbits; Rats; Trimethoprim, Sulfamethoxazole Drug Combination | 2005 |
The development of a cocktail CYP2B6, CYP2C8, and CYP3A5 inhibition assay and a preliminary assessment of utility in a drug discovery setting.
Topics: Aryl Hydrocarbon Hydroxylases; Biological Assay; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Design; Drug Interactions; Escherichia coli; Ketoconazole; Kinetics; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Quercetin; Ticlopidine | 2007 |
Roles of different CYP enzymes in the formation of specific fluvastatin metabolites by human liver microsomes.
Topics: Antibodies, Monoclonal; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Indoles; Ketoconazole; Microsomes, Liver; Quercetin; Sulfaphenazole | 2009 |
The application of in vitro technologies to study the metabolism of the androgenic/anabolic steroid stanozolol in the equine.
Topics: Anabolic Agents; Androgens; Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, Gas; Chromatography, High Pressure Liquid; Doping in Sports; Horses; Hydroxytestosterones; Ketoconazole; Microsomes, Liver; Molecular Structure; Quercetin; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Stanozolol; Substance Abuse Detection | 2010 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |