ketoconazole and prednisolone

ketoconazole has been researched along with prednisolone in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19906 (18.75)18.7374
1990's9 (28.13)18.2507
2000's6 (18.75)29.6817
2010's9 (28.13)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hiller, EJ1
Bhowmik, DM; Gandhi, BV; Jain, AK; Kale, S1
Frey, BM; Frey, FJ; Speck, RF; Ulrich, B1
Carey, T; Hirst, LW; Horsburgh, B; Nimmo, G; Stallard, K; Whitby, RM1
Jusko, WJ; Ludwig, EA; Middleton, E; Yamashita, SK1
Jasko, WJ1
Brass, C; Jusko, WJ; Ludwig, EA; Savliwala, M; Slaughter, RL1
Frey, BM; Frey, FJ; Zürcher, RM1
Pallister, CJ; Warnock, DW1
Anderson, PK; Benson, GD; Combes, B; Ishak, KG1
Baes, H; Van Cutsem, J1
den Dooven, D; Geerts, ML; van Hecke, E1
Kneale, B; Turton, C1
Bakr, MA; el-Sherif, AK; Foda, MA; Ghoneim, MA; Sally, S; Sobh, MA1
Cunningham, J; Holt, RI; Kwan, JT; Sefton, AM1
Chan, HL; Chiang, CT1
Braun, JJ; de Blay, F; Pauli, G1
Dubielzig, R; McAnulty, J; Penzo, C; Schmiedt, C; Schwab, M1
Altintas, O; Ay, GM; Cağlar, Y; Demirci, G; Karabas, LV; Tamer, GS1
Chiers, K; Croubels, S; Daminet, S; Ducatelle, R; Gadeyne, C; Hesta, M; Murua Escobar, H; Polis, I; Schauvliege, S; Sterenczak, K; Van der Heyden, S1
Casadei, MA; López-Cebral, R; Martin-Pastor, M; Paolicelli, P; Sanchez, A; Seijo, B1
Pramod, SV; Safriadi, F; Tresnanda, RI1
Nunes Rodrigues, TC; Vandenabeele, SI1

Reviews

3 review(s) available for ketoconazole and prednisolone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Superficial mycosis superimposing on isolated lichen planus of the lip: a case report and review of the literature.
    Cutis, 2002, Volume: 69, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antifungal Agents; Candidiasis; Diagnosis, Differential; Female; Griseofulvin; Humans; Ketoconazole; Lichen Planus, Oral; Lip; Prednisolone; Treatment Outcome

2002
Ketoconazole for the Treatment of Docetaxel-Naïve Metastatic Castration-Resistant Prostate Cancer (mCRPC): A Systematic Review.
    Asian Pacific journal of cancer prevention : APJCP, 2021, Oct-01, Volume: 22, Issue:10

    Topics: Adrenal Cortex Hormones; Antifungal Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Hydrocortisone; Ketoconazole; Male; Prednisolone; Prednisone; Progression-Free Survival; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Retrospective Studies

2021

Trials

3 trial(s) available for ketoconazole and prednisolone

ArticleYear
Concomitant administration of cyclosporine and ketoconazole in renal transplant patients.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Ketoconazole; Kidney Transplantation; Male; Prednisolone

1992
Lack of pharmacokinetic and pharmacodynamic interactions between ketoconazole and prednisolone.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:5

    Topics: Adult; Analysis of Variance; Basophils; Blood Proteins; Circadian Rhythm; Drug Evaluation; Drug Interactions; Histamine; Humans; Hydrocortisone; Ketoconazole; Leukocyte Count; Male; Prednisolone; Protein Binding; T-Lymphocytes, Helper-Inducer

1991
Different trends in immunosuppression: 10 years' experience with cyclosporine after living related donor renal transplantation.
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Adult; Azathioprine; Cause of Death; Cyclosporine; Drug Therapy, Combination; Family; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Ketoconazole; Kidney Transplantation; Male; Prednisolone; Retrospective Studies; Survival Rate; Time Factors; Tissue Donors; Transplantation, Homologous

1994

Other Studies

26 other study(ies) available for ketoconazole and prednisolone

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Aspergillosis.
    Journal of the Royal Society of Medicine, 1992, Volume: 85 Suppl 19

    Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Child; Cystic Fibrosis; Humans; Itraconazole; Ketoconazole; Male; Prednisolone; Radiography

1992
Pharmacokinetics/pharmacodynamics of ketoconazole-prednisolone interaction.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Drug Interactions; Hemocyanins; Hypersensitivity, Delayed; Ketoconazole; Male; Mice; Prednisolone; Prednisone

1992
Steroid sensitive Acanthamoeba keratitis.
    Australian and New Zealand journal of ophthalmology, 1991, Volume: 19, Issue:4

    Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Animals; Cornea; Female; Humans; Ketoconazole; Prednisolone; Recurrence; Visual Acuity

1991
Ketoconazole effects on corticosteroid disposition.
    Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:3

    Topics: Administration, Oral; Blood Proteins; Humans; Ketoconazole; Prednisolone; Prednisone

1990
Steroid-specific effects of ketoconazole on corticosteroid disposition: unaltered prednisolone elimination.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:11

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Circadian Rhythm; Humans; Ketoconazole; Male; Prednisolone; Prednisone

1989
Impact of ketoconazole on the metabolism of prednisolone.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:4

    Topics: Adult; Drug Interactions; Female; Humans; Ketoconazole; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Prednisolone; Prednisone

1989
Effect of antimicrobial and antineoplastic drugs alone and in combination on the phagocytic and candidacidal function of human polymorphonuclear leucocytes.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23, Issue:1

    Topics: Amphotericin B; Anti-Bacterial Agents; Antineoplastic Agents; Candida albicans; Cefuroxime; Ketoconazole; Methotrexate; Neutrophils; Phagocytosis; Prednisolone; Tobramycin; Vinblastine

1989
Prolonged jaundice following ketoconazole-induced hepatic injury.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:2

    Topics: Adult; Biopsy; Cholestasis; Humans; Hyperbilirubinemia; Ketoconazole; Liver; Male; Middle Aged; Prednisolone; Pruritus

1988
Primary cutaneous cryptococcosis.
    Dermatologica, 1985, Volume: 171, Issue:5

    Topics: Animals; Asthma; Columbidae; Cryptococcosis; Dermatomycoses; Humans; Immunosuppression Therapy; Ketoconazole; Male; Middle Aged; Prednisolone

1985
Petriellidiosis of the skin.
    Mykosen, 1983, Volume: 26, Issue:1

    Topics: Aged; Ascomycota; Dermatomycoses; Humans; Imidazoles; Ketoconazole; Male; Piperazines; Prednisolone

1983
Bronchoscopic findings in a case of bronchopulmonary histoplasmosis.
    Thorax, 1995, Volume: 50, Issue:3

    Topics: Amphotericin B; Biopsy; Bronchoscopy; Histoplasmosis; Humans; Ketoconazole; Lung Diseases, Fungal; Male; Middle Aged; Prednisolone; Respiratory Insufficiency

1995
Successful treatment of concomitant pulmonary nocardiosis and aspergillosis in an immunocompromised renal patient.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:2

    Topics: Adult; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cyclophosphamide; Drug Therapy, Combination; Humans; IgA Vasculitis; Imipenem; Immunocompromised Host; Itraconazole; Ketoconazole; Kidney Failure, Chronic; Lung; Lung Diseases, Fungal; Male; Nocardia Infections; Pneumonia; Prednisolone; Radiography; Renal Dialysis; Trimethoprim, Sulfamethoxazole Drug Combination

1993
[Allergic fungal sinusitis and allergic broncho-pulmonary aspergillosis: a fortuitous association or a nosological rhino-bronchial entity?].
    Revue des maladies respiratoires, 2005, Volume: 22, Issue:3

    Topics: Adult; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Aspergillus; Combined Modality Therapy; Endoscopy; Female; Flucytosine; Follow-Up Studies; Humans; Immunoglobulin E; Itraconazole; Ketoconazole; Male; Middle Aged; Mycoses; Prednisolone; Respiratory Hypersensitivity; Retrospective Studies; Sinusitis; Time Factors; Treatment Outcome

2005
Use of capecitabine after renal allograft transplantation in dog erythrocyte antigen-matched dogs.
    Veterinary surgery : VS, 2006, Volume: 35, Issue:2

    Topics: Animals; Blood Chemical Analysis; Capecitabine; Cyclosporine; Deoxycytidine; Dogs; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Female; Fluorouracil; Graft Rejection; Immunosuppressive Agents; Ketoconazole; Kidney Transplantation; Nephrectomy; Pilot Projects; Prednisolone; Prospective Studies; Transplantation Immunology; Transplantation, Homologous; Treatment Outcome

2006
Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage.
    Cornea, 2006, Volume: 25, Issue:3

    Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Antiprotozoal Agents; Benzamidines; Child, Preschool; Chlorhexidine; Contact Lenses; Cornea; Drug Therapy, Combination; Glucocorticoids; Humans; Ketoconazole; Male; Prednisolone

2006
Influence of P-glycoprotein modulation on plasma concentrations and pharmacokinetics of orally administered prednisolone in dogs.
    American journal of veterinary research, 2012, Volume: 73, Issue:6

    Topics: Administration, Oral; Analysis of Variance; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biopsy; Chromatography, Liquid; Dogs; Gene Expression Regulation; Ketoconazole; Prednisolone; Real-Time Polymerase Chain Reaction; Rifampin; Tandem Mass Spectrometry

2012
Application of NMR spectroscopy in the development of a biomimetic approach for hydrophobic drug association with physical hydrogels.
    Colloids and surfaces. B, Biointerfaces, 2014, Mar-01, Volume: 115

    Topics: Animals; Biomimetics; Cattle; Epitopes; Hydrogels; Hydrophobic and Hydrophilic Interactions; Ketoconazole; Ligands; Magnetic Resonance Spectroscopy; Prednisolone; Protein Binding; Serum Albumin, Bovine

2014
Pilot study of dogs with suppurative and non-suppurative Malassezia otitis: A case series.
    BMC veterinary research, 2021, Nov-18, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antifungal Agents; Dermatitis; Dog Diseases; Dogs; Ear Canal; Exudates and Transudates; Hypersensitivity; Immunoglobulin E; Intradermal Tests; Ketoconazole; Malassezia; Mometasone Furoate; Neutrophils; Otitis; Otitis Media, Suppurative; Prednisolone; Treatment Outcome; Triazoles

2021