ketoconazole and phenyl acetate

ketoconazole has been researched along with phenyl acetate in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (22.22)	18.7374
1990's	1 (11.11)	18.2507
2000's	3 (33.33)	29.6817
2010's	3 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hart, DT; Lauwers, WJ; Opperdoes, FR; Vanden Bossche, H; Willemsens, G	1
Geerts, H; Gorrens, J; Janssen, PA; Marichal, P; Vanden Bossche, H	1
Clark, RW; Gordon, DA; Parker, RA; Pearce, BC; Wright, JJ	1
Coker, NJ; Ho, T; Vrabec, JT; Yoo, D	1
Chang, SY; Cui, D; Li, W; Rodrigues, AD; Traeger, SC; Wang, B; Wen, B; Zhang, H	1
Antal, I; Klebovich, I; Kovács, K; Ludányi, K; Stampf, G	1
Hu, ML; Xu, M; Ye, Q	1
Camenisch, G; Chibale, K; Huth, F; Njuguna, NM; Schiller, H; Umehara, KI	1
Goda, H; Ito, K; Komatsu, S; Kudo, T; Tanaka, R; Yokosuka, Y	1

Trials

1 trial(s) available for ketoconazole and phenyl acetate

Article	Year
Quantitative determination of ketoconazole by UPLC-MS/MS in human plasma and its application to pharmacokinetic study. Drug research, 2014, Volume: 64, Issue:10 Topics: Acetates; Administration, Oral; Antifungal Agents; Asian People; Calibration; Capsules; China; Chromatography, Liquid; Healthy Volunteers; Humans; Ketoconazole; Linear Models; Liquid-Liquid Extraction; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2014

Article

Year

Quantitative determination of ketoconazole by UPLC-MS/MS in human plasma and its application to pharmacokinetic study.

Drug research, 2014, Volume: 64, Issue:10

Topics: Acetates; Administration, Oral; Antifungal Agents; Asian People; Calibration; Capsules; China; Chromatography, Liquid; Healthy Volunteers; Humans; Ketoconazole; Linear Models; Liquid-Liquid Extraction; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014

Other Studies

8 other study(ies) available for ketoconazole and phenyl acetate

Article	Year
Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages. Molecular and biochemical parasitology, 1989, Mar-01, Volume: 33, Issue:2 Topics: Acetates; Animals; Antiprotozoal Agents; Cell Division; Cell Line; Cholesterol; Ergosterol; Itraconazole; Ketoconazole; Leishmania mexicana; Macrophages; Sterols	1989
Mode of action studies. Basis for the search of new antifungal drugs. Annals of the New York Academy of Sciences, 1988, Volume: 544 Topics: Acetates; Antifungal Agents; Candida; Candida albicans; Cytochrome P-450 Enzyme System; Drug Design; Ergosterol; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Microsomes	1988
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15 Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E	1993
Otomycosis: clinical features and treatment implications. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 135, Issue:5 Topics: Acetates; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Child; Female; Humans; Ketoconazole; Male; Middle Aged; Mycoses; Otitis Externa; Recurrence; Retrospective Studies; Treatment Outcome	2006
Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:12 Topics: Acetates; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Catalysis; Cyclopropanes; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Genotype; Humans; Hydroxylation; Ibuprofen; Ketoconazole; Kinetics; Mephenytoin; Microsomes, Liver; Quinolines; Recombinant Proteins; Stereoisomerism; Sulfaphenazole; Sulfides; Tandem Mass Spectrometry	2008
Aqueous solvent system for the solubilization of azole compounds. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2009, Feb-15, Volume: 36, Issue:2-3 Topics: Acetates; Azoles; Calcium Gluconate; Ethanol; Glycerol; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Miconazole; Phosphoric Acids; Polyethylene Glycols; Polysorbates; Propylene Glycol; Solubility; Solvents; Surface-Active Agents; Water	2009
Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction. Drug metabolism and personalized therapy, 2016, 12-01, Volume: 31, Issue:4 Topics: Acetates; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Phenotype; Quinidine; Quinolines; Sulfaphenazole; Sulfides; Theophylline; Ticlopidine	2016
Estimation of the Contribution of CYP2C8 and CYP3A4 in Repaglinide Metabolism by Human Liver Microsomes Under Various Buffer Conditions. Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:9 Topics: Acetates; Buffers; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Humans; Hypoglycemic Agents; Ketoconazole; Microsomes, Liver; Piperidines; Quinolines; Sulfides	2017