ketoconazole and oxymorphone

ketoconazole has been researched along with oxymorphone in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (33.33)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Howald, W; Lalovic, B; Phillips, B; Risler, LL; Shen, DD	1
Drewe, J; Hammann, F; Krähenbühl, S; Kummer, O; Moser, C; Schaller, O	1

Reviews

1 review(s) available for ketoconazole and oxymorphone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for ketoconazole and oxymorphone

Article	Year
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. European journal of clinical pharmacology, 2011, Volume: 67, Issue:1 Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Genotype; Humans; Ketoconazole; Miosis; Morphinans; Oxycodone; Oxymorphone; Pain Measurement; Paroxetine; Placebos; Young Adult	2011

Article

Year

Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

European journal of clinical pharmacology, 2011, Volume: 67, Issue:1

Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Genotype; Humans; Ketoconazole; Miosis; Morphinans; Oxycodone; Oxymorphone; Pain Measurement; Paroxetine; Placebos; Young Adult

2011

Other Studies

4 other study(ies) available for ketoconazole and oxymorphone

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Metabolic Clearance Rate; Methylation; Microsomes; Microsomes, Liver; Molecular Structure; Morphinans; Oxidoreductases, N-Demethylating; Oxycodone; Oxymorphone; Protein Binding; Quinidine	2004