ketoconazole has been researched along with oxycodone in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Howald, W; Lalovic, B; Phillips, B; Risler, LL; Shen, DD | 1 |
| Daali, Y; Dayer, P; Desmeules, JA; Eap, CB; Hochstrasser, D; Hopfgartner, G; Rebsamen, MC; Rossier, MF; Samer, CF; Wagner, M | 1 |
| Drewe, J; Hammann, F; Krähenbühl, S; Kummer, O; Moser, C; Schaller, O | 1 |
1 review(s) available for ketoconazole and oxycodone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for ketoconazole and oxycodone
| Article | Year |
|---|---|
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Genotype; Humans; Ketoconazole; Male; Metabolic Detoxication, Phase I; Oxycodone; Phenotype; Polymorphism, Genetic; Quinidine; Receptors, Opioid, mu; Young Adult | 2010 |
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Genotype; Humans; Ketoconazole; Miosis; Morphinans; Oxycodone; Oxymorphone; Pain Measurement; Paroxetine; Placebos; Young Adult | 2011 |
1 other study(ies) available for ketoconazole and oxycodone
| Article | Year |
|---|---|
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Metabolic Clearance Rate; Methylation; Microsomes; Microsomes, Liver; Molecular Structure; Morphinans; Oxidoreductases, N-Demethylating; Oxycodone; Oxymorphone; Protein Binding; Quinidine | 2004 |