ketoconazole has been researched along with orteronel in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Asahi, S; Hara, T; Hitaka, T; Kaku, T; Kusaka, M; Miki, H; Takahashi, J; Takeuchi, T; Tasaka, A; Yamaoka, M | 1 |
| Abbott, DH; Bird, IM | 1 |
| Chapman, JG; Guengerich, FP; McCarty, KD; Tateishi, Y | 1 |
1 review(s) available for ketoconazole and orteronel
| Article | Year |
|---|---|
The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature.
Topics: Adrenal Hyperplasia, Congenital; Androstadienes; Androstenes; Antineoplastic Agents; Benzimidazoles; Cytochrome P-450 CYP3A Inhibitors; Drug Therapy, Combination; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Male; Naphthalenes; Prednisone; Prostate; Prostatic Neoplasms; Protective Factors; Steroid 17-alpha-Hydroxylase; Triazoles | 2016 |
2 other study(ies) available for ketoconazole and orteronel
| Article | Year |
|---|---|
Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys.
Topics: Adrenal Glands; Androgen Antagonists; Androgens; Animals; Cell Line, Tumor; Cells, Cultured; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Macaca fascicularis; Male; Naphthalenes; Orchiectomy; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone | 2012 |
Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis.
Topics: Androgens; Androstenes; Antineoplastic Agents, Hormonal; Catalytic Domain; Cytochrome P-450 CYP3A; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Kinetics; Male; Naphthalenes; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase | 2021 |