ketoconazole and nifurtimox

ketoconazole has been researched along with nifurtimox in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's5 (45.45)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aguirre, G; Boiani, L; Boiani, M; Castro, A; Cerecetto, H; Ferreira, A; González, M; Hernández, P; Maio, RD; Merlino, A; Porcal, W1
Aguirre, G; Basombrío, MA; Boiani, L; Boiani, M; Campillo, NE; Castro, A; Cazzulo, JJ; Cerecetto, H; Chidichimo, A; Davies, C; González, M; Hernández, P; Krauth-Siegel, RL; Paez, JA; Porcal, W1
Boiani, L; Boiani, M; Cazzulo, JJ; Cerecetto, H; Chidichimo, A; Ferreira, A; González, M; Hernández, P; Olea-Azar, C; Porcal, W1
Aguirre, G; Aldana, I; Barreiro, EJ; Cerecetto, H; González, M; Hernández, P; Lima, LM; Monge, A; Pérez-Silanes, S; Romeiro, NC1
Alvarez, G; Benítez, D; Boiani, L; Cerecetto, H; Gerpe, A; González, M; Hernández, P; Quiroga, M; Sortino, M; Zacchino, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Boiani, L; Cerecetto, H; Gerpe, A; González, M; Hernández, P; Sortino, M; Zacchino, S1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Jennings, FW1
Lazardi, K; Liendo, A; Molina, J; Payares, G; Perez, N; Piras, MM; Piras, R; Ryley, JF; Sanoja, C; Urbina, JA; Wincker, P1
Hanson, WL; Kinnamon, KE; Poon, BT; Waits, VB1

Other Studies

11 other study(ies) available for ketoconazole and nifurtimox

ArticleYear
Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2007, Apr-01, Volume: 15, Issue:7

    Topics: Animals; Benzoxazoles; Cell Line; Cell Survival; Humans; Indicators and Reagents; Macrophages; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2007
In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Animals; Antibodies, Protozoan; Benzoxazoles; Cell Line; Chagas Disease; Cysteine Endopeptidases; Female; Glutathione; Humans; Macrophages; Mice; Models, Molecular; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxygen Consumption; Protozoan Proteins; Stereoisomerism; Structure-Activity Relationship; Sulfones; Trypanocidal Agents; Trypanosoma cruzi; Vinyl Compounds

2007
New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle.
    Bioorganic & medicinal chemistry, 2008, Jul-15, Volume: 16, Issue:14

    Topics: Animals; Benzoxazoles; Cysteine Endopeptidases; Glutathione; Hydrazones; Macrophages; Mice; Oxidative Stress; Protozoan Proteins; Spermidine; Trypanocidal Agents; Trypanosoma cruzi

2008
Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Animals; Binding Sites; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Hydrazones; Inhibitory Concentration 50; Macrophages; Mice; Nifurtimox; Protozoan Proteins; Quinoxalines; Trypanocidal Agents; Trypanosoma cruzi

2009
5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene.
    Bioorganic & medicinal chemistry, 2009, Nov-01, Volume: 17, Issue:21

    Topics: Animals; Chagas Disease; Drug Design; Humans; Mice; Nitrofurans; Quantitative Structure-Activity Relationship; Squalene; Squalene Monooxygenase; Thiophenes; Trypanocidal Agents; Trypanosoma cruzi

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Naftifine-analogues as anti-Trypanosoma cruzi agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Allylamine; Animals; Cell Line; Drug Design; Fungi; Inhibitory Concentration 50; Mice; Microbial Sensitivity Tests; Squalene; Trypanocidal Agents; Trypanosoma cruzi

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2

    Topics: Animals; Antiprotozoal Agents; Arsenicals; Brain Diseases; Drug Synergism; Drug Therapy, Combination; Female; Ketoconazole; Metronidazole; Mice; Nifurtimox; Nitro Compounds; Nitroimidazoles; Oxidation-Reduction; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991
Cure of short- and long-term experimental Chagas' disease using D0870.
    Science (New York, N.Y.), 1996, Aug-16, Volume: 273, Issue:5277

    Topics: Animals; Base Sequence; Chagas Disease; Drug Administration Schedule; Ketoconazole; Molecular Sequence Data; Nifurtimox; Sterols; Time Factors; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

1996
In pursuit of drugs for American trypanosomiasis: evaluation of some "standards" in a mouse model.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 216, Issue:3

    Topics: Animals; Antiprotozoal Agents; Chagas Disease; Disease Models, Animal; Female; Imipramine; Ketoconazole; Mice; Mice, Inbred Strains; Nifurtimox; Nigericin; Niridazole; Protriptyline; Trypanosoma cruzi

1997