ketoconazole and n-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium

ketoconazole has been researched along with n-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Castagnoli, N; Fukui, M; Igarashi, K; Kasuya, F; Usuki, E	1
Kalgutkar, AS; Nguyen, HT	1

Other Studies

2 other study(ies) available for ketoconazole and n-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium

Article	Year
Studies on the metabolism of haloperidol (HP): the role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following ip administration of HP. Life sciences, 1995, Nov-17, Volume: 57, Issue:26 Topics: Animals; Antibodies; Antipsychotic Agents; Biotransformation; Brain; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Haloperidol; Injections, Intraperitoneal; Ketoconazole; Male; Microsomes, Liver; Mitochondria; Mixed Function Oxygenases; Nifedipine; Pyridinium Compounds; Rats; Rats, Sprague-Dawley	1995
Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antidiarrheals; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Haloperidol; Humans; Hydroxylation; Ketoconazole; Loperamide; Male; Microsomes, Liver; NADP; Neurons; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Time Factors	2004

Article

Year

Studies on the metabolism of haloperidol (HP): the role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following ip administration of HP.

Life sciences, 1995, Nov-17, Volume: 57, Issue:26

Topics: Animals; Antibodies; Antipsychotic Agents; Biotransformation; Brain; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Haloperidol; Injections, Intraperitoneal; Ketoconazole; Male; Microsomes, Liver; Mitochondria; Mixed Function Oxygenases; Nifedipine; Pyridinium Compounds; Rats; Rats, Sprague-Dawley

1995

Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.

Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:9

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antidiarrheals; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Haloperidol; Humans; Hydroxylation; Ketoconazole; Loperamide; Male; Microsomes, Liver; NADP; Neurons; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Time Factors

2004