ketoconazole and mitotane

ketoconazole has been researched along with mitotane in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.56)	18.7374
1990's	12 (30.77)	18.2507
2000's	8 (20.51)	29.6817
2010's	14 (35.90)	24.3611
2020's	4 (10.26)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Nichols, R	2
Takeda, R	1
Crapo, L; Miller, JW	1
Dluhy, RG; Solomon, CG	1
Kintzer, PP; Peterson, ME	2
Bruyette, DS; Myers, NC	1
Engelhardt, D	1
Caillé, JM; Catargi, B; Drouillard, J; Greselle, JF; Laurent, F; Martigne, C; Roger, P; Tabarin, A	1
Nishikawa, T; Saito, J	1
Rosenthal, KL	1
Behrend, EN; Clark, TP; Kemppainen, RJ; Peterson, ME; Salman, MD	1
Ito, N; Morishita, K; Okumura, H; Takahashi, N	1
Peterson, ME	1
Ramé, A	1
Billalabeitia, EG; Carmona-Bayonas, A; Díaz, MP; Gómez, FI; Saura, HP; Soler, IO; Tafalla, MS	1
Brown, CG; Graves, TK	1
Dang, CN; Trainer, P	1
Bertagna, X; Fierrard, H; Raffin-Sanson, ML; Rosales, C	1
Alexandraki, KI; Grossman, AB	1
Greenman, Y	1
de Herder, WW; Feelders, RA; Hofland, LJ	1
Baudin, E; Blanchard, A; Brailly-Tabard, S; Chanson, P; Droumaguet, C; Gautier, JF; Jublanc, C; Kamenický, P; Leboulleux, S; Salenave, S; Schlumberger, M; Young, J	1
Biller, BM; Tritos, NA	1
Barahona Constanzo, MJ; del Pozo Picó, C	1
Gadelha, MR; Vieira Neto, L	1
Broder, MS; Chang, E; Cherepanov, D; Ludlam, WH; Neary, MP; Sun, GH	1
Daniel, E; Newell-Price, JD	1
Hu, S; Infantino, D; Lubitz, S; Ohri, A; Sedhom, R	1
Biller, BMK; Tritos, NA	1
Braun, LT; Reincke, M	1
Tritos, NA	1
Boguszewski, CL; Marques, JVO	1
Hull, B; Wedrychowicz, A	1

Reviews

26 review(s) available for ketoconazole and mitotane

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Problems associated with medical therapy of canine hyperadrenocorticism. Problems in veterinary medicine, 1990, Volume: 2, Issue:4 Topics: Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Animals; Cushing Syndrome; Diabetes Mellitus, Type 1; Dog Diseases; Dogs; Ketoconazole; Mitotane	1990
[Clinical studies on a disorder of mineralocorticoid metabolism]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1986, Volume: 75, Issue:2 Topics: Aldosterone; Humans; Hyperaldosteronism; Kanamycin; Ketoconazole; Metyrapone; Mineralocorticoids; Mitotane; Mixed Function Oxygenases	1986
The medical treatment of Cushing's syndrome. Endocrine reviews, 1993, Volume: 14, Issue:4 Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dogs; Horses; Humans; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Octreotide; Palliative Care; Pituitary Gland; Radiography; Valproic Acid	1993
Medical treatment of pituitary-dependent hyperadrenocorticism in dogs. Seminars in veterinary medicine and surgery (small animal), 1994, Volume: 9, Issue:3 Topics: Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dog Diseases; Dogs; Drug Administration Schedule; Ketoconazole; Mitotane; Selegiline	1994
Concurrent illness and complications associated with canine hyperadrenocorticism. Seminars in veterinary medicine and surgery (small animal), 1994, Volume: 9, Issue:3 Topics: Acute Disease; Animals; Cushing Syndrome; Diabetes Complications; Diabetes Mellitus; Dog Diseases; Dogs; Hypertension; Ketoconazole; Mitotane; Pancreatitis; Pituitary Neoplasms; Pulmonary Embolism; Urologic Diseases	1994
Feline adrenocortical diseases: Part I--Hyperadrenocorticism. Seminars in veterinary medicine and surgery (small animal), 1994, Volume: 9, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Cat Diseases; Cats; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Dogs; Humans; Ketoconazole; Metyrapone; Mitotane; Tomography, X-Ray Computed	1994
Steroid biosynthesis inhibitors in Cushing's syndrome. The Clinical investigator, 1994, Volume: 72, Issue:7 Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane	1994
[Clinical usefulness of pharmacological treatment of Cushing's syndrome]. Nihon rinsho. Japanese journal of clinical medicine, 1994, Volume: 52, Issue:3 Topics: Administration, Oral; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Humans; Ketoconazole; Metyrapone; Mitotane	1994
Diagnosis and management of canine cortisol-secreting adrenal tumors. The Veterinary clinics of North America. Small animal practice, 1997, Volume: 27, Issue:2 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antifungal Agents; Antineoplastic Agents; Dog Diseases; Dogs; Hydrocortisone; Ketoconazole; Mitotane; Prognosis	1997
Adrenal gland disease in ferrets. The Veterinary clinics of North America. Small animal practice, 1997, Volume: 27, Issue:2 Topics: Adrenal Cortex Function Tests; Adrenal Gland Diseases; Adrenal Glands; Animals; Antifungal Agents; Antineoplastic Agents; Blood Chemical Analysis; Diagnosis, Differential; Female; Ferrets; Ketoconazole; Male; Mitotane; Prognosis; Radiography; Tomography, X-Ray Computed; Ultrasonography	1997
Medical treatment of canine pituitary-dependent hyperadrenocorticism (Cushing's disease). The Veterinary clinics of North America. Small animal practice, 2001, Volume: 31, Issue:5 Topics: Animals; Antifungal Agents; Cushing Syndrome; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Ketoconazole; Mitotane; Monoamine Oxidase Inhibitors; Pituitary Diseases; Pituitary Gland; Selegiline; Treatment Outcome	2001
Hyperadrenocorticism: treating dogs. Compendium (Yardley, PA), 2007, Volume: 29, Issue:3 Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Drug Therapy, Combination; Ketoconazole; Mitotane; Prognosis; Treatment Outcome	2007
[Management of hypercortisolism]. La Revue de medecine interne, 2008, Volume: 29, Issue:4 Topics: Antineoplastic Agents, Hormonal; Cushing Syndrome; Decision Trees; Enzyme Inhibitors; Humans; Hypophysectomy; Ketoconazole; Mitotane; Pituitary Gland	2008
Medical therapy of Cushing's disease: where are we now? Frontiers of hormone research, 2010, Volume: 38 Topics: Dopamine Agonists; Humans; Hydrocortisone; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin	2010
Management of dyslipidemia in Cushing's syndrome. Neuroendocrinology, 2010, Volume: 92 Suppl 1 Topics: Cushing Syndrome; Dyslipidemias; Enzyme Inhibitors; Humans; Ketoconazole; Mitotane	2010
Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole. Neuroendocrinology, 2010, Volume: 92 Suppl 1 Topics: Cushing Syndrome; Enzyme Inhibitors; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane	2010
Advances in medical therapies for Cushing's syndrome. Discovery medicine, 2012, Volume: 13, Issue:69 Topics: Animals; Bexarotene; Cushing Syndrome; Etomidate; Humans; Ketoconazole; Lapatinib; Metyrapone; Mifepristone; Mitotane; Quinazolines; Somatostatin; Tetrahydronaphthalenes	2012
New prospects for drug treatment in Cushing disease. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10 Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Ergolines; Etomidate; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Metyrapone; Mice; Mifepristone; Mitotane; Multicenter Studies as Topic; Pituitary ACTH Hypersecretion; Pituitary Neoplasms; PPAR gamma; Pyridines; Rats; Somatostatin; Therapies, Investigational; Tretinoin	2012
Efficacy of medical treatment in Cushing's disease: a systematic review. Clinical endocrinology, 2014, Volume: 80, Issue:1 Topics: Cabergoline; Ergolines; Female; Humans; Ketoconazole; Male; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin	2014
Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome. European journal of endocrinology, 2015, Volume: 172, Issue:6 Topics: Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Pyridines; Steroid Synthesis Inhibitors	2015
Medical Management of Cushing Disease. Neurosurgery clinics of North America, 2019, Volume: 30, Issue:4 Topics: Cabergoline; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin; Temozolomide; Treatment Outcome	2019
What is the role of medical therapy in adrenal-dependent Cushing's syndrome? Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:3 Topics: Adrenal Gland Diseases; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Prospective Studies; Treatment Outcome	2020
Adrenally Directed Medical Therapies for Cushing Syndrome. The Journal of clinical endocrinology and metabolism, 2021, 01-01, Volume: 106, Issue:1 Topics: Adrenal Glands; Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Molecular Targeted Therapy; Pyridines	2021
Medical therapy in severe hypercortisolism. Best practice & research. Clinical endocrinology & metabolism, 2021, Volume: 35, Issue:2 Topics: Cabergoline; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane	2021
The function of adrenal glands in children and adolescents during and after oncological treatment. Pediatric endocrinology, diabetes, and metabolism, 2022, Volume: 28, Issue:3 Topics: Adolescent; Adrenal Glands; Child; Etomidate; Fluconazole; Humans; Hypothalamo-Hypophyseal System; Immune Checkpoint Inhibitors; Ketoconazole; Metyrapone; Mitotane; Pituitary-Adrenal System; Quality of Life	2022

Other Studies

13 other study(ies) available for ketoconazole and mitotane

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Paraneoplastic endocrine syndromes. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndrome; Diazoxide; Diphosphonates; Estrogens; Fluid Therapy; Hemangiopericytoma; Humans; Hypercalcemia; Hyperthyroidism; Hypoglycemia; Inappropriate ADH Syndrome; Ketoconazole; Mifepristone; Mineralocorticoids; Mitotane; Octreotide; Osteomalacia; Pamidronate; Paraneoplastic Endocrine Syndromes; Phosphorus; Plicamycin; Propylthiouracil; Saline Solution, Hypertonic; Somatostatin; Thyroid Neoplasms	1994
[Paraneoplastic Cushing's syndrome. Pseudotumors of the thymus occurring after correction of hypercorticism. 3 cases]. Presse medicale (Paris, France : 1983), 1993, Dec-04, Volume: 22, Issue:38 Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adult; Carcinoid Tumor; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Ketoconazole; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mitotane; Thymus Hyperplasia; Tomography, X-Ray Computed	1993
Treatment of hyperadrenocorticism in dogs: a survey of internists and dermatologists. Journal of the American Veterinary Medical Association, 1999, Oct-01, Volume: 215, Issue:7 Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Antineoplastic Agents, Hormonal; Dog Diseases; Dogs; Glucocorticoids; Ketoconazole; Mitotane; Pituitary Neoplasms; Prednisone; Surveys and Questionnaires	1999
Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis. Toxicology, 2001, Aug-28, Volume: 165, Issue:2-3 Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aminoglutethimide; Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Dogs; Female; Ketoconazole; Metyrapone; Miconazole; Mitotane; Toxicity Tests	2001
[Cushing syndrome]. Revue de l'infirmiere, 2007, Issue:129 Topics: Adrenalectomy; Causality; Cushing Syndrome; Humans; Hydrocortisone; Ketoconazole; Magnetic Resonance Imaging; Mitotane; Tomography, X-Ray Computed	2007
Tailored hormonal therapy in secretory adrenocortical cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7 Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Captopril; Cisplatin; Diarrhea; Doxorubicin; Etoposide; Female; Heart Failure; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypokalemia; Ketoconazole; Mineralocorticoid Receptor Antagonists; Mitotane; Neoplasm Recurrence, Local; Potassium; Rhabdomyolysis; Spironolactone; Tachycardia	2007
Pharmacological management of Cushing's syndrome: an update. Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:8 Topics: Cushing Syndrome; Dopamine Antagonists; Hormone Antagonists; Humans; Hypothalamo-Hypophyseal System; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary-Adrenal System; PPAR gamma; Somatostatin; Steroids	2007
Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:9 Topics: Adolescent; Adult; Aged; Antimetabolites; Antineoplastic Agents; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Ketoconazole; Male; Metyrapone; Middle Aged; Mitotane; Treatment Outcome	2011
Treatment patterns in Cushing's disease patients in two large United States nationwide databases: application of a novel, graphical methodology. Pituitary, 2015, Volume: 18, Issue:4 Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenalectomy; Adult; Antineoplastic Agents, Hormonal; Cohort Studies; Cytochrome P-450 CYP3A Inhibitors; Databases, Factual; Dopamine Agonists; Female; Humans; Hypophysectomy; Ketoconazole; Male; Middle Aged; Mitotane; Pituitary ACTH Hypersecretion; Practice Patterns, Physicians'; Radiotherapy; Retrospective Studies; United States	2015
Symptomatic Cushing's syndrome and hyperandrogenemia in a steroid cell ovarian neoplasm: a case report. Journal of medical case reports, 2016, Oct-12, Volume: 10, Issue:1 Topics: Aged; Antineoplastic Agents, Hormonal; Cushing Syndrome; Disease Progression; Fatal Outcome; Female; Humans; Hyperandrogenism; Ketoconazole; Mitotane; Ovarian Neoplasms; Practice Guidelines as Topic; Rare Diseases; Sex Cord-Gonadal Stromal Tumors; Spironolactone	2016