Compounds > ketoconazole

ketoconazole and miltefosine

ketoconazole has been researched along with miltefosine in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (28.57)	29.6817
2010's	10 (71.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Battista, MR; Brun, R; Calvet, CM; Cirilli, R; Costi, R; De Leo, A; De Vita, D; Di Marco, A; Di Santo, R; Faggi, C; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pepe, G; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Summa, V; Tudino, V	1
Braga, SS	1
Castanys, S; Castanys-Muñoz, E; Gamarro, F; Pérez-Victoria, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM	1
Chen, X; Ding, HF; Lang, L; Liu, G; Sun, SY; Yan, C	1
Birchmore, JL; Hanson, PK; Malone, L; Nichols, JW	1
Barbosa, HS; de Castro, SL; Lira, R; Santa-Rita, RM; Urbina, JA	1
Berman, J	1
Fedorko, DP; Mahanty, S; Nash, TE; Ramanathan, R; Talaat, KR	1
Bavchvarov, BI; Campillo, M; Castanys, S; Gamarro, F; López-Martín, C; Martínez-García, M; Pérez-Victoria, JM; Torrecillas, IR	1
Bajpai, P; Gupta, S; Sane, SA; Shakya, N; Vishwakarma, P	1
Jiang, J; Mathur, R; Pandharkar, T; Schmittgen, TD; Shaha, C; Werbovetz, KA; Zhu, X	1
Heli, H; Karimian, K; Motazedian, MH; Nazari-Vanani, R; Sattarahmady, N; Sharifi, F; Vais, RD	1

Reviews

2 review(s) available for ketoconazole and miltefosine

Article	Year
Multi-target drugs active against leishmaniasis: A paradigm of drug repurposing. European journal of medicinal chemistry, 2019, Dec-01, Volume: 183 Topics: Amphotericin B; Antifungal Agents; Drug Repositioning; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Leishmaniasis; Molecular Targeted Therapy; Phosphorylcholine; Sterol 14-Demethylase; Triazoles; Voriconazole	2019
Clinical status of agents being developed for leishmaniasis. Expert opinion on investigational drugs, 2005, Volume: 14, Issue:11 Topics: Aminoquinolines; Antiprotozoal Agents; Fluconazole; Humans; Imiquimod; Ketoconazole; Leishmaniasis; Paromomycin; Phosphorylcholine	2005

Other Studies

12 other study(ies) available for ketoconazole and miltefosine

Article	Year
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Parasitic Sensitivity Tests; Trypanosoma	2019
Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Aminoquinolines; Animals; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Base Sequence; Biological Transport, Active; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genes, Protozoan; Humans; Leishmania infantum; Leishmaniasis, Visceral; Lipid Bilayers; Phosphorylcholine; Protozoan Proteins; Recombinant Proteins; Transformation, Genetic	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:3 Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase	2011
Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds. Chemistry & biology, 2015, Jul-23, Volume: 22, Issue:7 Topics: CRISPR-Cas Systems; Gene Targeting; Genes; Genes, Reporter; Genetic Engineering; Humans; Internal Ribosome Entry Sites; Transcription, Genetic	2015
Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine. The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38 Topics: Alleles; Antiprotozoal Agents; Biological Transport; Cell Division; Cell Membrane; Cycloheximide; Dose-Response Relationship, Drug; Drug Resistance; Drug Resistance, Multiple; Endocytosis; Gene Deletion; Ketoconazole; Leishmaniasis; Lipid Metabolism; Lysophosphatidylcholines; Membrane Transport Proteins; Microscopy, Fluorescence; Mutation; Nuclear Envelope; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phosphodiesterase Inhibitors; Phospholipid Ethers; Phosphorylcholine; Point Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors	2003
Anti-proliferative synergy of lysophospholipid analogues and ketoconazole against Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae): cellular and ultrastructural analysis. The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:5 Topics: Animals; Chlorocebus aethiops; Drug Synergism; Drug Therapy, Combination; Ergosterol; Ketoconazole; Lysophospholipids; Microscopy, Electron; Microscopy, Electron, Scanning; Parasitic Sensitivity Tests; Phospholipid Ethers; Phosphorylcholine; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells	2005
A species-specific approach to the use of non-antimony treatments for cutaneous leishmaniasis. The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:1 Topics: Adult; Aged; Amphotericin B; Antiprotozoal Agents; Child; Female; Humans; Ketoconazole; Leishmania; Leishmaniasis, Cutaneous; Male; Middle Aged; Phosphorylcholine; Species Specificity	2011
Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8 Topics: Aminoquinolines; Antimony; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Drug Resistance, Bacterial; Ketoconazole; Leishmania tropica; Leishmaniasis; Phosphorylcholine; Protein Binding	2011
Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv. Acta tropica, 2011, Volume: 119, Issue:2-3 Topics: Animals; Antiprotozoal Agents; Cinnamates; Cricetinae; Disease Models, Animal; Drug Therapy, Combination; Female; Glycosides; Hydrogen Peroxide; Immunologic Factors; Ketoconazole; Leishmania donovani; Leishmaniasis, Visceral; Male; Phagocytosis; Phosphorylcholine; Reactive Nitrogen Species; Reactive Oxygen Species; Rodent Diseases; Treatment Outcome; Vanillic Acid	2011
Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Amidines; Animals; Antiprotozoal Agents; Axenic Culture; Blotting, Western; Cricetinae; Drug Combinations; Drug Resistance; Drug Synergism; Furans; Gene Expression Regulation; Ketoconazole; Leishmania donovani; Life Cycle Stages; Mice; Phosphorylcholine; Protozoan Proteins; Sterol 14-Demethylase; Triazoles	2014
Investigation of anti-leishmanial efficacy of miltefosine and ketoconazole loaded on nanoniosomes. Acta tropica, 2018, Volume: 185 Topics: Animals; Antiprotozoal Agents; Ketoconazole; Leishmania major; Leishmaniasis, Cutaneous; Nanostructures; Phosphorylcholine	2018