ketoconazole and mevalonic acid

ketoconazole has been researched along with mevalonic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, DJ; Brown, SB; Dickinson, K; Evans, EG; Hitchcock, CA1
Panini, SR; Schnitzer-Polokoff, R; Sinensky, M; Spencer, TA1
Gibbons, GF; Iglesias, J1
Gupta, A; Rudney, H; Sexton, RC1
Beach, DH; Berman, JD; Goad, LJ; Holz, GG1
Beach, DH; Goad, LJ; Holz, GG1
Ryder, NS1
Clark, RW; Gordon, DA; Parker, RA; Pearce, BC; Wright, JJ1
González-Pacanowska, D; Hurtado, R; Montalvetti, A; Peña-Díaz, J; Ruiz-Pérez, LM1
Guo, X; Liu, W; Liu, Y; Peng, C; Shen, H; Wang, Q; Wang, X; Zhao, ZK1

Other Studies

10 other study(ies) available for ketoconazole and mevalonic acid

ArticleYear
Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alpha-sterol demethylase purified from Candida albicans.
    The Biochemical journal, 1990, Mar-01, Volume: 266, Issue:2

    Topics: Antifungal Agents; Azoles; Candida albicans; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ferric Compounds; Ketoconazole; Mevalonic Acid; Oxidoreductases; Spectrum Analysis; Sterol 14-Demethylase; Triazoles

1990
Sterol-independent regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by mevalonate in Chinese hamster ovary cells. Magnitude and specificity.
    The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19

    Topics: Acetyl-CoA C-Acetyltransferase; Animals; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Dose-Response Relationship, Drug; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Synthase; Ketoconazole; Lanosterol; Mevalonic Acid; Naphthols; Squalene; Sterols

1989
Regulation of hepatic cholesterol biosynthesis. Effects of a cytochrome P-450 inhibitor on the formation and metabolism of oxygenated sterol products of lanosterol.
    The Biochemical journal, 1989, Dec-01, Volume: 264, Issue:2

    Topics: Animals; Biotransformation; Cell-Free System; Cells, Cultured; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Lanosterol; Liver; Male; Mevalonic Acid; Oxidoreductases; Rats; Rats, Inbred Strains; Sterol 14-Demethylase; Subcellular Fractions

1989
Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestina
    The Journal of biological chemistry, 1986, Jun-25, Volume: 261, Issue:18

    Topics: Animals; Cholesterol; Cholesterol Esters; Cytochrome P-450 Enzyme System; Epithelium; Hydroxymethylglutaryl CoA Reductases; Intestines; Ketoconazole; Lipoproteins, LDL; Mevalonic Acid; Models, Chemical; Oleic Acid; Oleic Acids; Rats; Sterol O-Acyltransferase; Sterols

1986
Effects of ketoconazole on sterol biosynthesis by Leishmania mexicana mexicana amastigotes in murine macrophage tumor cells.
    Molecular and biochemical parasitology, 1986, Volume: 20, Issue:1

    Topics: Animals; Cell Line; Ketoconazole; Leishmania mexicana; Macrophages; Mevalonic Acid; Mice; Sterols

1986
Sterols of ketoconazole-inhibited Leishmania mexicana mexicana promastigotes.
    Molecular and biochemical parasitology, 1985, Volume: 15, Issue:3

    Topics: Animals; Cholesterol; Chromatography, Gas; Cytochrome P-450 Enzyme System; Ketoconazole; Lanosterol; Leishmania; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mevalonic Acid; Sterols

1985
Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:2

    Topics: Allylamine; Animals; Antifungal Agents; Candida; Cell-Free System; Cholesterol; Ergosterol; Hydrogen-Ion Concentration; In Vitro Techniques; Ketoconazole; Liver; Male; Mevalonic Acid; Naphthalenes; Rats; Squalene; Sterols; Terbinafine; Trichophyton

1985
Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    The Journal of biological chemistry, 1993, May-25, Volume: 268, Issue:15

    Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E

1993
Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase.
    The Biochemical journal, 2000, Jul-01, Volume: 349, Issue:Pt 1

    Topics: Amino Acid Sequence; Ammonium Sulfate; Animals; Blotting, Northern; Blotting, Western; Cell Membrane; Cells, Cultured; Chromatography; Chromatography, Gel; Chromosome Mapping; Durapatite; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketoconazole; Kinetics; Leishmania major; Lovastatin; Mevalonic Acid; Molecular Sequence Data; Protein Structure, Tertiary; RNA Processing, Post-Transcriptional; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2000
Enabling Heterologous Synthesis of Lupulones in the Yeast Saccharomyces cerevisiae.
    Applied biochemistry and biotechnology, 2019, Volume: 188, Issue:3

    Topics: Genes, Plant; Humulus; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Mevalonic Acid; Saccharomyces cerevisiae; Terpenes

2019