Compounds > ketoconazole

ketoconazole and methoxsalen

ketoconazole has been researched along with methoxsalen in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, X; Ding, HF; Lang, L; Liu, G; Sun, SY; Yan, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dushkin, MI; Menshikova, EB; Pivovarova, EN; Volsky, NN; Zenkov, NK1
Ashton, M; Svensson, US1
Chiba, K; Kobayashi, K; Shimada, N; Urashima, K1
Kamataki, T; Kawai, R; Murai, K; Nakagawa, K; Yamazaki, H1

Reviews

1 review(s) available for ketoconazole and methoxsalen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for ketoconazole and methoxsalen

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds.
    Chemistry & biology, 2015, Jul-23, Volume: 22, Issue:7

    Topics: CRISPR-Cas Systems; Gene Targeting; Genes; Genes, Reporter; Genetic Engineering; Humans; Internal Ribosome Entry Sites; Transcription, Genetic

2015
Ketoconazole inhibits oxidative modification of low density lipoprotein.
    Atherosclerosis, 1995, Apr-07, Volume: 114, Issue:1

    Topics: Animals; Benzoflavones; Benzopyrene Hydroxylase; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ketoconazole; Lipoproteins, LDL; Luminescent Measurements; Macrophages, Peritoneal; Methoxsalen; Metyrapone; Mice; Mice, Inbred Strains; Oxidation-Reduction

1995
Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:4

    Topics: Antimalarials; Artemisinins; Aryl Hydrocarbon Hydroxylases; Cell Line; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Drug Interactions; Humans; Isoenzymes; Ketoconazole; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; Orphenadrine; Oxidoreductases, N-Demethylating; Regression Analysis; Sesquiterpenes; Time Factors; Troleandomycin

1999
Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:7

    Topics: Aniline Compounds; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; DNA, Complementary; Enzyme Inhibitors; Gene Expression; Humans; Isoenzymes; Ketoconazole; Methoxsalen; Microsomes, Liver; Quinidine; Rats; Steroid 16-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Sulfaphenazole; Theophylline

2003
Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:11

    Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Cross-Linking Reagents; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Genotype; Humans; Ketoconazole; Letrozole; Methoxsalen; Microsomes, Liver; Nitriles; Oxidoreductases; Steroid Hydroxylases; Triazoles

2009