ketoconazole has been researched along with lignans in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Parker, RS; Sontag, TJ; Swanson, JE | 1 |
| Hiratsuka, A; Iwata, H; Kadota, S; Tezuka, Y; Watabe, T | 1 |
| Kadota, S; Tezuka, Y; Usia, T; Watabe, T | 1 |
| Huang, Q; Jia, YW; Wang, GJ; Xie, HT; Xu, MJ | 1 |
| Cao, YF; Fang, ZZ; Ge, GB; Hu, D; Huang, T; Huo, H; Li, J; Liu, HX; Sun, DX; Wang, YC; Yang, L; Yin, J; Zhang, YY | 1 |
| Dumrongsakulchai, W; Navinpipat, V; Somanabandhu, A; Taesotikul, T; Tassaneeyakul, W; Wattanachai, N | 1 |
| Li, WL; Su, MW; Xin, HW | 1 |
| Pickova, J; Vestergren, AS; Zamaratskaia, G; Zlabek, V | 1 |
| Li, WL; Wu, XC; Xin, HW; Yu, AR | 1 |
| Chengqing, L; Chenming, N; Tao, L; Xiaoyang, L | 1 |
| Chen, JM; Fang, JS; Huang, MJ; Li, WR; Liang, Y; Lin, MJ; Liu, JM; Ma, CR; Wang, Q; Wu, FC; Yu, WQ; Zuo, X | 1 |
11 other study(ies) available for ketoconazole and lignans
| Article | Year |
|---|---|
Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin.
Topics: Antioxidants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Lignans; Liver; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Tumor Cells, Cultured; Vitamin E | 2000 |
Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dioxoles; Enzyme Inhibitors; Erythromycin; Female; Humans; In Vitro Techniques; Ketoconazole; Lignans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microdialysis; Microsomes, Liver; Optical Rotation; Plant Extracts; Polycyclic Compounds; Schisandra; Solvents | 2004 |
Potent CYP3A4 inhibitory constituents of Piper cubeba.
Topics: Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Fruit; Humans; Indonesia; Inhibitory Concentration 50; Ketoconazole; Lignans; Microsomes, Liver; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Piper; Plants, Medicinal; Stereoisomerism | 2005 |
[Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes].
Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Cyclooctanes; Enzyme Inhibitors; Female; In Vitro Techniques; Ketoconazole; Lignans; Male; Microsomes, Liver; Orphenadrine; Plants, Medicinal; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Schisandra; Sex Factors; Spectrophotometry, Ultraviolet | 2007 |
CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.
Topics: Animals; Catalysis; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Humans; Ketoconazole; Lignans; Mass Spectrometry; Metabolic Networks and Pathways; Microsomes, Liver; Polycyclic Compounds; Rats; Swine; Swine, Miniature; Troleandomycin | 2010 |
Inhibitory effects of Phyllanthus amarus and its major lignans on human microsomal cytochrome P450 activities: evidence for CYP3A4 mechanism-based inhibition.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Herb-Drug Interactions; Humans; Inhibitory Concentration 50; Ketoconazole; Lignans; Microsomes, Liver; Phyllanthus; Plant Extracts | 2011 |
Inhibitory effects of continuous ingestion of Schisandrin A on CYP3A in the rat.
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Ketoconazole; Lignans; Male; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 2012 |
Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diclofenac; Dioxoles; Ellipticines; Fish Proteins; Fluconazole; Hydroxylation; Ketoconazole; Kinetics; Lignans; Microsomes, Liver; Oxazines; Salmo salar; Sulfaphenazole; Tolbutamide | 2012 |
In vivo effect of Schisandrin B on cytochrome P450 enzyme activity.
Topics: Administration, Oral; Animals; Biological Availability; Cyclooctanes; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Ketoconazole; Lignans; Liver; Male; Medicine, Chinese Traditional; Microsomes, Liver; Midazolam; Polycyclic Compounds; Rats; Rats, Sprague-Dawley | 2013 |
Drug-drug interation prediction between ketoconazole and anti-liver cancer drug Gomisin G.
Topics: Antineoplastic Agents; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxoles; Drug Interactions; Humans; Ketoconazole; Lignans; Liver; Liver Neoplasms; Molecular Docking Simulation; Plant Extracts; Schisandra | 2015 |
Screening and verification of CYP3A4 inhibitors from Bushen-Yizhi formula to enhance the bioavailability of osthole in rat plasma.
Topics: Animals; Antifungal Agents; Biological Availability; Coumarins; Cyclooctanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dioxoles; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gene Expression Regulation, Enzymologic; Herb-Drug Interactions; Ketoconazole; Lignans; Male; Polycyclic Compounds; Random Allocation; Rats; Rats, Sprague-Dawley | 2022 |