ketoconazole and leuprolide

ketoconazole has been researched along with leuprolide in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's5 (41.67)18.2507
2000's0 (0.00)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Huben, RP1
McConnell, JD1
English, HF; Levine, HB; Santen, RJ; Santner, SJ1
Trachtenberg, J1
Feuillan, PP1
Carpenter, PC; Turk, DM1
DeAngelis, LM; Mencel, PJ; Motzer, RJ1
Chi, T; Lue, TF; Mwamukonda, KB; Shindel, AW1
Aoun, P; Sharma, AN; Veldhuis, JD; Weist, SM; Wigham, JR1
Balk, SP; Bubley, GJ; Cai, C; Chen, EJ; Gao, S; Kantoff, PW; Lis, RL; Loda, M; Montgomery, RB; Nelson, PS; Schaefer, R; Sowalsky, AG; Taplin, ME; Troncoso, P; True, LD; Voznesensky, O; Ye, H1

Reviews

1 review(s) available for ketoconazole and leuprolide

ArticleYear
Physiologic basis of endocrine therapy for prostatic cancer.
    The Urologic clinics of North America, 1991, Volume: 18, Issue:1

    Topics: Aminoglutethimide; Androgen Antagonists; Androgens; Estrogens; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Leuprolide; Male; Orchiectomy; Progestins; Prostatic Neoplasms

1991

Trials

2 trial(s) available for ketoconazole and leuprolide

ArticleYear
Hormone therapy of prostatic bone metastases.
    Advances in experimental medicine and biology, 1992, Volume: 324

    Topics: Actuarial Analysis; Androgen Antagonists; Bone Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Goserelin; Humans; Ketoconazole; Leuprolide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Remission Induction; Spironolactone; Survival Rate

1992
Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Volume: 306, Issue:9

    Topics: Adrenocorticotropic Hormone; Age Factors; Aging; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Enzyme Inhibitors; Estradiol; Feedback, Physiological; Female; Humans; Hydrocortisone; Hypogonadism; Hypothalamo-Hypophyseal System; Infusions, Intravenous; Ketoconazole; Leuprolide; Male; Middle Aged; Pituitary-Adrenal System; Prospective Studies; Protein Binding; Serum Albumin; Serum Albumin, Human; Sex Factors; Testosterone; Time Factors; Transcortin

2014

Other Studies

9 other study(ies) available for ketoconazole and leuprolide

ArticleYear
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Inhibition of testosterone production with ketoconazole alone and in combination with a gonadotropin releasing hormone analogue in the rat.
    Cancer research, 1986, Volume: 46, Issue:1

    Topics: Animals; Drug Synergism; Gonadotropin-Releasing Hormone; Ketoconazole; Leuprolide; Luteinizing Hormone; Male; Organ Size; Prostate; Rats; Testosterone; Time Factors

1986
The effects of ketoconazole on testosterone production and normal and malignant androgen dependent tissues of the adult rat.
    The Journal of urology, 1984, Volume: 132, Issue:3

    Topics: Adenocarcinoma; Animals; Castration; Depression, Chemical; Gonadotropin-Releasing Hormone; Half-Life; Ketoconazole; Leuprolide; Male; Neoplasms, Hormone-Dependent; Organ Size; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Testosterone

1984
McCune-Albright syndrome.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adolescent; Calcitriol; Diagnosis, Differential; Female; Fibrous Dysplasia, Polyostotic; Humans; Ketoconazole; Leuprolide; Male; Medroxyprogesterone Acetate; Octreotide; Ovariectomy; Propylthiouracil; Puberty, Precocious; Spironolactone; Testolactone; Thyroid Diseases

1994
Hirsutism.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Androgen Antagonists; Bromocriptine; Contraceptives, Oral, Combined; Dexamethasone; Female; Finasteride; Goserelin; Hirsutism; Humans; Ketoconazole; Leuprolide; Medroxyprogesterone Acetate; Nafarelin

1994
Hormonal ablation as effective therapy for carcinomatous meningitis from prostatic carcinoma.
    Cancer, 1994, Apr-01, Volume: 73, Issue:7

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Flutamide; Follow-Up Studies; Humans; Ketoconazole; Leuprolide; Male; Meningeal Neoplasms; Meningitis; Prostatic Neoplasms

1994
Androgen blockade for the treatment of high-flow priapism.
    The journal of sexual medicine, 2010, Volume: 7, Issue:7

    Topics: Adult; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents, Hormonal; Erectile Dysfunction; Humans; Ketoconazole; Leuprolide; Male; Middle Aged; Nitriles; Penile Erection; Priapism; Retrospective Studies; Surveys and Questionnaires; Tosyl Compounds; Ultrasonography; Young Adult

2010
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Mar-15, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; DNA Helicases; DNA-Binding Proteins; Drug Resistance, Neoplasm; Dutasteride; Humans; Ketoconazole; Leuprolide; Male; Middle Aged; Mutation; Progesterone; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Receptors, Androgen; Steroid 17-alpha-Hydroxylase

2015