ketoconazole has been researched along with letrozole in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 9 (60.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mandi, P; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S | 1 |
| Boonsombat, J; Chawengrum, P; Eurtivong, C; Kittakoop, P; Mahidol, C; Ruchirawat, S; Thongnest, S | 1 |
| Barrow, D; Eissa, AG; Foster, PA; Gee, J; Powell, LE; Simons, C | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Akagi, T; Kajimoto, T; Katoh, T; Nishizawa née Iwamoto, M; Node, M; Noguchi, C; Ohtsu, H; Saito, K; Suzuki, N; Tanaka, R | 1 |
| Majetich, G; Shimkus, JM | 1 |
| Muftuoglu, Y; Mustata, G | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Mandi, P; Nantasenamat, C; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kamataki, T; Kawai, R; Murai, K; Nakagawa, K; Yamazaki, H | 1 |
| Nantasenamat, C; Pingaew, R; Prachayasittikul, S; Prachayasittikul, V; Ruchirawat, S | 1 |
| Chi, Z; Ding, L; Li, L; Ma, P; Shu, C; Tao, L; Wang, K; Wei, J; Wu, Y | 1 |
| Bureik, M; Durairaj, P; Fan, L; Jie, Z; Sharma, SS | 1 |
2 review(s) available for ketoconazole and letrozole
| Article | Year |
|---|---|
The taiwaniaquinoids: a review.
Topics: Biological Products; Cupressaceae; Diterpenes; Molecular Structure | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for ketoconazole and letrozole
| Article | Year |
|---|---|
A highly sensitive LC-MS/MS method for determination of ketoconazole in human plasma: Application to a clinical study of the exposure to ketoconazole in patients after topical administration.
Topics: Administration, Topical; Adult; Chromatography, High Pressure Liquid; Dermatitis, Seborrheic; Drug Stability; Humans; Ketoconazole; Letrozole; Liquid-Liquid Extraction; Nitriles; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles; Young Adult | 2016 |
12 other study(ies) available for ketoconazole and letrozole
| Article | Year |
|---|---|
Synthesis, molecular docking, and QSAR study of sulfonamide-based indoles as aromatase inhibitors.
Topics: Animals; Aromatase; Aromatase Inhibitors; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Indoles; Molecular Docking Simulation; Molecular Structure; Multivariate Analysis; Quantitative Structure-Activity Relationship; Sulfonamides; Vero Cells | 2018 |
Diterpenoids with Aromatase Inhibitory Activity from the Rhizomes of
Topics: Abietanes; Aromatase Inhibitors; Cell Line, Tumor; Diterpenes; Humans; Molecular Structure; Rhizome; Thailand; Zingiberaceae | 2021 |
4th generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors.
Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Receptors, Estrogen; Triazoles | 2022 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Synthesis of DL-standishinal and its related compounds for the studies on structure-activity relationship of inhibitory activity against aromatase.
Topics: Aromatase Inhibitors; Catalysis; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diterpenes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thuja | 2007 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors.
Topics: Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Catalytic Domain; Cell Survival; Chlorocebus aethiops; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Isoquinolines; Molecular Docking Simulation; Protein Binding; Structure-Activity Relationship; Sulfonamides; Triazoles; Vero Cells | 2015 |
Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes.
Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Cross-Linking Reagents; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Genotype; Humans; Ketoconazole; Letrozole; Methoxsalen; Microsomes, Liver; Nitriles; Oxidoreductases; Steroid Hydroxylases; Triazoles | 2009 |
Investigation of aromatase inhibitory activity of metal complexes of 8-hydroxyquinoline and uracil derivatives.
Topics: Aromatase Inhibitors; Cell Line; Coordination Complexes; Copper; Humans; Inhibitory Concentration 50; Ketoconazole; Letrozole; Lung; Manganese; Nickel; Nitriles; Oxyquinoline; Triazoles; Uracil | 2014 |
Identification of new probe substrates for human CYP20A1.
Topics: Cytochrome P-450 Enzyme System; Humans; Imidazoles; Ketoconazole; Letrozole; Molecular Structure; Substrate Specificity | 2020 |