ketoconazole and kanamycin a

ketoconazole has been researched along with kanamycin a in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's1 (5.00)18.2507
2000's5 (25.00)29.6817
2010's13 (65.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Buarque De Gusmao, N; Guiraud, P; Seigle-Murandi, F; Steiman, R1
Ge, HM; Li, HQ; Shi, L; Song, YC; Tan, RX; Tan, SH; Zhu, HL1
Gui, SY; Li, HQ; Shi, L; Xue, JY; Zhu, HL1
Cao, P; Gu, W; Shi, L; Tan, SH; Zhang, LN; Zhu, HL1
Fang, RQ; Li, HQ; Xiao, ZP; Xue, JY; Zheng, Y; Zhu, HL1
da Silva, IM; de Albuquerque, JF; de Oliveira, RM; de Oliveira, TB; de Sena, KX; do Nascimento, SC; Gouveia, FL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cheng, K; Jiao, QC; Liu, K; Zhang, XM; Zheng, QZ; Zhu, HL1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, LH; He, XB; Peng, J; Peng, ZY; Xiao, ZP; Xiong, TJ; Zhu, HL1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Huang, ZJ; Lv, PC; Ouyang, H; Wang, XD; Xiao, ZP; Yang, YL; Yi, TF; Yu, SR; Zhu, HL1
Deng, Y; Feng, YT; Li, JL; Li, ZP; Liang, X; Liao, ML; Luo, Q; Ma, TW; Peng, XC; Wu, Y; Xiao, ZP; Zhu, HL1
Deng, RC; Dong, JJ; Gao, XM; Li, ST; Lin, WQ; Lu, CL; Peng, ZY; Wang, XD; Xiao, ZP; Zhu, HL1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Takeda, R1

Reviews

2 review(s) available for ketoconazole and kanamycin a

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Clinical studies on a disorder of mineralocorticoid metabolism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1986, Volume: 75, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Kanamycin; Ketoconazole; Metyrapone; Mineralocorticoids; Mitotane; Mixed Function Oxygenases

1986

Other Studies

18 other study(ies) available for ketoconazole and kanamycin a

ArticleYear
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Antimicrobial and antitumor activities of mycosporulone.
    Journal of natural products, 1999, Volume: 62, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Cyclohexanes; Drug Screening Assays, Antitumor; Fungi; Humans; Microbial Sensitivity Tests; Spiro Compounds; Tumor Cells, Cultured

1999
Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:4

    Topics: Aldehydes; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Molecular Structure; Schiff Bases

2007
Synthesis, crystal structure and antimicrobial activity of deoxybenzoin derivatives from genistein.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Anti-Infective Agents; Bacteria; Benzoin; Crystallography, X-Ray; Genistein; Microbial Sensitivity Tests; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet

2008
Synthesis and antimicrobial activities of 7-O-modified genistein derivatives.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:7

    Topics: Anti-Bacterial Agents; Genistein; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization

2008
Enamines as novel antibacterials and their structure-activity relationships.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:9

    Topics: Amines; Anti-Infective Agents; Bacteria; Crystallography, X-Ray; Drug Evaluation, Preclinical; Fungi; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship

2008
Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Gram-Positive Bacteria; Humans; Ketones; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazolidines

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis of some N-alkyl substituted urea derivatives as antibacterial and antifungal agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:7

    Topics: Alkanes; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Urea

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Synthesis, structure, molecular docking, and structure-activity relationship analysis of enamines: 3-aryl-4-alkylaminofuran-2(5H)-ones as potential antibacterials.
    Bioorganic & medicinal chemistry, 2011, Mar-01, Volume: 19, Issue:5

    Topics: Amines; Anti-Bacterial Agents; Crystallography, X-Ray; Furans; Models, Molecular; Molecular Structure; Nitro Compounds; Staphylococcus aureus; Structure-Activity Relationship; Tyrosine-tRNA Ligase

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
4-alkoxy-3-arylfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking and antibacterial evaluation.
    Bioorganic & medicinal chemistry, 2011, Jul-01, Volume: 19, Issue:13

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Binding Sites; Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Furans; Microbial Sensitivity Tests; Molecular Conformation; Morpholines; Staphylococcus aureus; Structure-Activity Relationship; Tyrosine-tRNA Ligase

2011
Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: synthesis, molecular docking and structure-activity relationship analysis of 3-aryl-4-arylaminofuran-2(5H)-ones.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Anti-Bacterial Agents; Enzyme Inhibitors; Furans; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Models, Molecular; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Tyrosine-tRNA Ligase

2011
3-Aryl-4-acyloxyethoxyfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking and antibacterial evaluation.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Anti-Infective Agents; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Fungi; Furans; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Docking Simulation; Staphylococcus aureus; Structure-Activity Relationship; Thermodynamics; Tyrosine-tRNA Ligase

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
    Journal of natural products, 2013, Nov-22, Volume: 76, Issue:11

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells

2013