ketoconazole has been researched along with isoxazoles in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, SD; DeCory, TR; Georgiev, VS; Kinsolving, CR; Mitchell, JT; Mullen, GB | 1 |
| Allen, SD; Kinsolving, CR; Mullen, GB; Ordy, JM; Palmer, GC; Simmons, RD; St Georgiev, V; Strand, JC | 1 |
| Kitada, M; Kiuchi, M; Nakamura, H; Nakasa, H; Ohmori, S; Ono, S; Tsutsui, M | 1 |
| Tschirret-Guth, RA; Wood, HB | 1 |
| Boonleang, J; Mahatthanatrakul, W; Pipatrattanaseree, W; Ridtitid, W; Rujimamahasan, N; Sriwiriyajan, S; Wongnawa, M | 1 |
| Greenhaw, J; Salminen, WF; Shi, Q; Yang, X | 1 |
| Hochfeld, M; Meng, X; Potkin, SG; Preskorn, S | 1 |
| Emmerich, IU | 1 |
| Banpurkar, AR; Perdih, F; Wazalwar, SS | 1 |
2 trial(s) available for ketoconazole and isoxazoles
| Article | Year |
|---|---|
Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Half-Life; Humans; Isoxazoles; Ketoconazole; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Tandem Mass Spectrometry; Tissue Distribution; Young Adult | 2012 |
A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult | 2013 |
7 other study(ies) available for ketoconazole and isoxazoles
| Article | Year |
|---|---|
Studies on antifungal agents. 23. Novel substituted 3,5-diphenyl-3-(1H-imidazol-1-ylmethyl)- 2-alkylisoxazolidine derivatives.
Topics: Animals; Antifungal Agents; Candidiasis; Imidazoles; Isoxazoles; Ketoconazole; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Mitosporic Fungi; Oxazoles; Rats; Structure-Activity Relationship | 1988 |
Comparisons of ketoconazole, PR 969-566, PR 967-234, and PR 967-248 as antifungals in vitro and in the rat model of candidal vaginitis based on efficacy/safety profiles.
Topics: Animals; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Disease Models, Animal; Female; Fungi; Isoxazoles; Ketoconazole; Microbial Sensitivity Tests; Oxazoles; Rats | 1988 |
Prediction of drug-drug interactions of zonisamide metabolism in humans from in vitro data.
Topics: Anticonvulsants; Cyclosporine; Cytochrome P-450 Enzyme System; Dihydroergotamine; Drug Interactions; Humans; In Vitro Techniques; Isoxazoles; Itraconazole; Ketoconazole; Metabolic Clearance Rate; Miconazole; Triazolam; Zonisamide | 1998 |
Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes.
Topics: Air; Amidines; Animals; Carbon Monoxide; Chemistry Techniques, Analytical; Cytochrome P-450 Enzyme System; Electrons; Indoles; Isoxazoles; Ketoconazole; Microsomes, Liver; Molecular Structure; NADP; Oxazoles; Oxidation-Reduction; Rats; Structure-Activity Relationship | 2003 |
Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes.
Topics: Aniline Compounds; Animals; Benzoflavones; Biomarkers; Cell Survival; Cells, Cultured; Crotonates; Cytochrome P-450 Enzyme System; Hepatocytes; Hydroxybutyrates; Inactivation, Metabolic; Isoxazoles; Ketoconazole; Leflunomide; Liver; Male; Nitriles; Primary Cell Culture; Proadifen; Rats; Rats, Sprague-Dawley; Ticlopidine; Toluidines; Triazoles | 2011 |
[New drugs for small animals in 2014].
Topics: Animals; Cats; Dogs; Guanidines; Insulin; Isoxazoles; Ketoconazole; Naphthalenes; Neonicotinoids; Nitro Compounds; Pyrimidines; Sulfonamides; Veterinary Drugs | 2015 |
Synthesis, crystal structure and molecular docking study of novel isoxazole derivatives as CYP450 inhibitors in search of anticancer agents.
Topics: Antineoplastic Agents; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Erlotinib Hydrochloride; Isoxazoles; Ketoconazole; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2023 |