ketoconazole has been researched along with indomethacin in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.00) | 18.7374 |
| 1990's | 14 (28.00) | 18.2507 |
| 2000's | 11 (22.00) | 29.6817 |
| 2010's | 21 (42.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF | 1 |
| Batt, DG; Collins, RJ; Corbett, RL; Green, AM; Harris, RR; Wadman, EA; Wright, SW | 1 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| el-Gazzar, AB; Hafez, HN; Nawwar, GA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Apostolidis, I; Ćirić, A; Gavalas, A; Geronikaki, A; Glamočlija, J; Hadjipavlou-Litina, D; Liaras, K; Soković, M | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Coceani, F; De Marte, J; Perreault, T | 1 |
| Agarwal, KC; Tzanakakis, GN; Veronikis, DK; Vezeridis, MP | 1 |
| Bonventre, JV; Sellmayer, A; Uedelhoven, WM; Weber, PC | 1 |
| Clark, JE; Harder, DR; Kauser, K; Ma, YH; Masters, BS; Ortiz de Montellano, PR; Roman, RJ | 1 |
| Capdevila, J; Falck, JR; Gil, L; Marnett, LJ; Mason, JI; Orellana, M; Yadagiri, P | 1 |
| Capdevila, JH; Falck, JR; Kaminski, PM; Proctor, KG; Shatkin, S | 1 |
| Alvarez, E; Colombato, LO; Guma, C; Lami, G; Miyashiro, R; Olmos, M | 1 |
| Hechtman, HB; Krausz, MM; Levine, L; Shepro, D; Utsonomiya, T | 1 |
| Owyang, C; Tsunoda, Y | 1 |
| Kersting, D; Kersting, U; Spring, KR | 1 |
| Nakamura, S; Nomura, T; Ryoyama, K | 1 |
| Abe, K; Omata, K; Sato, T; Sheu, HL; Shimizu, T; Tsutsumi, E; Utsumi, Y | 1 |
| Bayer, AL; Koop, DR; Laethem, CL; Simonson, MS; Thibonnier, M | 1 |
| Kasiske, BL; Keane, WF; Kim, Y; O'Donnell, MP | 1 |
| Kersting, U; Napathorn, S; Spring, KR | 1 |
| Berndt, TJ; Khraibi, AA; Ramsey, CR; Taylor, KH | 1 |
| Akard, L; Boswell, HS; Carlo-Stella, C; Dugan, M; Garau, D; Regazzi, E; Rizzo, MT; Rizzoli, V | 1 |
| Al Moutaery, AR | 1 |
| Afrakhteh, M; Givtaj, N; Hassantash, SA; Omrani, GR | 1 |
| Bhugra, C; Krill, SL; Pikal, MJ; Shmeis, R | 1 |
| Abdel-Moty, SG; Abou-Ghadir, OM; Hussein, MA; Kafafy, AH | 1 |
| Guardiola, J; Li, H; Lin, S; Moldoveanu, B; Xu, L; Yu, J | 1 |
| Hubert, M; Li, J; Pan, D; Patel, J; Raghavan, K; Tao, L; Waknis, V; Wang, J; Zhao, J | 1 |
| Li, J; Wang, Y; Wu, B | 1 |
| Brouillet, F; Franceschi, S; Martin, B; Perez, E | 1 |
2 review(s) available for ketoconazole and indomethacin
| Article | Year |
|---|---|
Recently reported biological activities of pyrazole compounds.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles | 2017 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for ketoconazole and indomethacin
| Article | Year |
|---|---|
Pharmacological prevention of the deleterious effects of cardiopulmonary bypass.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation; C-Reactive Protein; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Coagulants; Complement C3; Complement C4; Double-Blind Method; Female; Humans; Immunoglobulins; Indomethacin; Inflammation; Ketoconazole; Male; Middle Aged; Postoperative Hemorrhage; Prospective Studies; Reoperation; Respiration, Artificial; Time Factors; Treatment Outcome | 2007 |
47 other study(ies) available for ketoconazole and indomethacin
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dermatitis; Edema; Imidazoles; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Phospholipases A; Pyridines; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1992 |
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.
Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Carrageenan; Drug Discovery; Edema; Female; Lipid Peroxidation; Male; Mice; Microwaves; Nucleosides; Quinolines; Rats | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Edema; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Thiazoles | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Evidence against the involvement of a cytochrome P-450 mechanism in pulmonary hemodynamics in the newborn pig.
Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Indomethacin; Isoenzymes; Ketoconazole; Lipoxygenase Inhibitors; Metyrapone; Perfusion; Pulmonary Circulation; Swine | 1991 |
Effects of antiplatelet agents alone or in combinations on platelet aggregation and on liver metastases from a human pancreatic adenocarcinoma in the nude mouse.
Topics: Adenocarcinoma; Animals; Colforsin; Drug Interactions; Humans; Indomethacin; Ketoconazole; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Platelet Aggregation; Platelet Aggregation Inhibitors; Tumor Cells, Cultured; Verapamil | 1991 |
Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Blotting, Northern; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Epidermal Growth Factor; Gas Chromatography-Mass Spectrometry; Glomerular Mesangium; Indomethacin; Ketoconazole; Male; Masoprocol; Pyridines; Rats; Rats, Inbred WKY; RNA, Messenger; Tetradecanoylphorbol Acetate | 1991 |
Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dogs; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Ketoconazole; Kinetics; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Phosphorylcholine; Proadifen; Renal Artery; Triazoles | 1991 |
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Indomethacin; Ketoconazole; Male; Masoprocol; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains | 1988 |
Modulation of arteriolar blood flow by inhibitors of arachidonic acid oxidation after thermal injury: possible role for a novel class of vasodilator metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Arterioles; Burns; Cheek; Cricetinae; Cytochrome P-450 Enzyme System; Indomethacin; Ischemia; Ketoconazole; Male; Mouth Mucosa; Oxidation-Reduction; Pyrazoles; Regional Blood Flow; Vasoconstriction; Vasodilation; Vasodilator Agents | 1988 |
[Hepatic lesions induced by drugs. Report of 26 cases].
Topics: Adult; Aged; Biopsy; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Estrogens; Female; Humans; Indomethacin; Ketoconazole; Liver; Male; Methyldopa; Middle Aged; Penicillins | 1987 |
Thromboxane mediation of cardiopulmonary effects of embolism.
Topics: Animals; Dogs; Epoprostenol; Female; Heart; Imidazoles; Indomethacin; Ketoconazole; Male; Piperazines; Platelet Count; Pulmonary Embolism; Thromboxane A2; Thromboxanes; Time Factors; Vascular Resistance | 1982 |
A newly cloned phospholipase A2-activating protein elicits Ca2+ oscillations and pancreatic amylase secretion via mediation of G protein beta/phospholipase A2/arachidonic acid cascades.
Topics: Aminobenzoates; Amylases; Animals; Arachidonic Acids; Calcium; Chlorobenzoates; Cinnamates; Cloning, Molecular; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Ketoconazole; Kinetics; Macromolecular Substances; Male; ortho-Aminobenzoates; Pancreas; Phospholipases A; Phospholipases A2; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Time Factors | 1994 |
Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells.
Topics: Absorption; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Hydrogen-Ion Concentration; Indomethacin; Ion Channels; Ketoconazole; Masoprocol; Membrane Potentials; Membrane Proteins; Proadifen; Thionucleotides; Transfection | 1993 |
Inhibition of macrophage nitric oxide production by arachidonate-cascade inhibitors.
Topics: Acetophenones; Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Caffeic Acids; Dexamethasone; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione Transferase; Indomethacin; Ketoconazole; Lipoxygenase; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Phospholipases A; Phospholipases A2; Sodium Nitrite; Umbelliferones | 1993 |
Epoxyeicosatrienoic acids stimulate the growth of vascular smooth muscle cells.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cell Division; Epoprostenol; Epoxy Compounds; Flavanones; Flavonoids; Indomethacin; Ketoconazole; Mesenteric Veins; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Thymidine | 1995 |
Role of eicosanoids in vasopressin-induced calcium mobilization in A7r5 vascular smooth muscle cells.
Topics: Animals; Arachidonic Acid; Arginine Vasopressin; Biological Transport; Calcium; Cell Line; Eicosanoids; Electrophysiology; Indomethacin; Intracellular Membranes; Ketoconazole; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular | 1993 |
Oxidative modification of low-density lipoproteins by mesangial cells.
Topics: Antioxidants; Arachidonic Acid; Butylated Hydroxytoluene; Catalase; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; DNA Replication; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Hydroxyurea; Indomethacin; Ketoconazole; Lipoproteins, LDL; Lipoxygenase Inhibitors; Masoprocol; Oxidation-Reduction; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 1993 |
Necturus gallbladder epithelial cell volume regulation and inhibitors of arachidonic acid metabolism.
Topics: Animals; Arachidonic Acids; Cell Membrane Permeability; Chlorides; Cytochrome P-450 Enzyme System; Epithelial Cells; Epithelium; Gallbladder; Indomethacin; Ketoconazole; Masoprocol; Necturus maculosus; Osmosis; Sodium | 1993 |
Blockade of cytochrome P-450 epoxygenase pathway attenuates the natriuresis of N(G)-monomethyl-L-arginine infusion in the spontaneously hypertensive rat.
Topics: Age Factors; Animals; Antifungal Agents; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diuresis; Dose-Response Relationship, Drug; Indomethacin; Ketoconazole; Male; Nephrons; Nitric Oxide; omega-N-Methylarginine; Oxygenases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1997 |
Induction of apoptosis by arachidonic acid in chronic myeloid leukemia cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Animals; Antioxidants; Apoptosis; Arachidonic Acid; Bone Marrow Cells; Caffeic Acids; Cell Division; Colony-Forming Units Assay; Erythroid Precursor Cells; Female; Hematopoietic Stem Cells; Humans; Indomethacin; Ketoconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Masoprocol; Mice; Middle Aged; Tumor Cells, Cultured | 1999 |
Protective effect of ketoconazole against experimentally induced gastric ulcers in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Ethanol; Female; Immunologic Factors; Indomethacin; Ketoconazole; Ligation; Male; Rats; Stomach Ulcer | 2003 |
Prediction of onset of crystallization from experimental relaxation times. II. Comparison between predicted and experimental onset times.
Topics: Algorithms; Calorimetry; Chemical Phenomena; Chemistry, Physical; Crystallization; Electrochemistry; Forecasting; Hydrogen Bonding; Indomethacin; Ketoconazole; Microscopy, Polarization; Models, Chemical; Models, Statistical; Nifedipine; Temperature; Thermodynamics | 2008 |
Synthesis and biological activities of new substituted thiazoline-quinoline derivatives.
Topics: Acetophenones; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Edema; Fluoroquinolones; Fungi; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Indomethacin; Ketoconazole; Lethal Dose 50; Male; Mice; Quinolines; Rats; Stomach Ulcer; Thiazoles; Toxicity Tests, Acute | 2009 |
Arachidonic acid products in airway nociceptor activation during acute lung injury.
Topics: Acute Lung Injury; Animals; Arachidonic Acid; Indomethacin; Ketoconazole; Male; Nociceptors; Oleic Acid; Rabbits; Thromboxane-A Synthase | 2011 |
The effect of polymeric excipients on the physical properties and performance of amorphous dispersions: Part I, free volume and glass transition.
Topics: Excipients; Glass; Indomethacin; Ketoconazole; Polymers; Transition Temperature | 2015 |
Evaluation of the Microcentrifuge Dissolution Method as a Tool for Spray-Dried Dispersion.
Topics: Centrifugation; Chemistry, Pharmaceutical; Indomethacin; Ketoconazole; Solubility | 2016 |
Evaluation of Organogel Nanoparticles as Drug Delivery System for Lipophilic Compounds.
Topics: Drug Carriers; Drug Liberation; Gels; Indomethacin; Ketoconazole; Nanoparticles; Particle Size; Temperature | 2017 |