ketoconazole has been researched along with imatinib mesylate in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Capdeville, R; Dutreix, C; Hayes, M; Mehring, G; Peng, B; Pokorny, R; Seiberling, M | 1 |
| Fujita, S; Ishizuka, M; Nagai, S; Sakamoto, KQ | 1 |
| Bukhari, NI; Chay, G; Kan, E; Law, JH; Lim, WY; Segarra, I; Soo, GW; Tan, SY | 1 |
| Han, A; Hu, G; Kan, X; Lin, G; Qiu, X; Wang, C; Wang, Z; Xu, T | 1 |
| Beumer, JH; Christner, SM; Kiesel, BF; Parise, RA; Pillai, VC; Rudek, MA; Venkataramanan, R | 1 |
| Arenas-Ramírez, A; Cervera-Ceballos, E; Garcia-Lopez, P; Jurado, R; Llaguno-Munive, M; Pérez-Rojas, J; Prado-Carrillo, O | 1 |
1 trial(s) available for ketoconazole and imatinib mesylate
| Article | Year |
|---|---|
Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects.
Topics: Adult; Antineoplastic Agents; Benzamides; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Humans; Imatinib Mesylate; Ketoconazole; Male; Middle Aged; Piperazines; Pyrimidines | 2004 |
7 other study(ies) available for ketoconazole and imatinib mesylate
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Plasma pharmacokinetics and CYP3A12-dependent metabolism of c-kit inhibitor imatinib in dogs.
Topics: Animals; Antineoplastic Agents; Benzamides; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Female; Haplorhini; Humans; Imatinib Mesylate; Ketoconazole; Male; Microsomes, Liver; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Rats; Time Factors | 2007 |
Differential effects of ketoconazole and primaquine on the pharmacokinetics and tissue distribution of imatinib in mice.
Topics: Animals; Antifungal Agents; Antimalarials; Antineoplastic Agents; Benzamides; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Imatinib Mesylate; Ketoconazole; Male; Mice; Mice, Inbred ICR; Piperazines; Primaquine; Pyrimidines; Tissue Distribution | 2010 |
Differential effects of ketoconazole, itraconazole and voriconazole on the pharmacokinetics of imatinib and its main metabolite GCP74588 in rat.
Topics: Animals; Antifungal Agents; Benzamides; Drug Interactions; Imatinib Mesylate; Itraconazole; Ketoconazole; Male; Piperazines; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Voriconazole | 2014 |
Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Hepatocytes; Humans; Imatinib Mesylate; Ketoconazole; Male; Middle Aged; Primary Cell Culture; Rifampin; Ritonavir; Young Adult | 2015 |
Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Doxorubicin; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Ketoconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Kinase Inhibitors | 2022 |