ketoconazole and hypericum

ketoconazole has been researched along with hypericum in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansen, TS; Nilsen, OG1
Burhenne, J; Fuchs, I; Haefeli, WE; Hafner-Blumenstiel, V; Markert, C; Mikus, G; Weiss, J1

Trials

1 trial(s) available for ketoconazole and hypericum

ArticleYear
Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:3

    Topics: Adult; Area Under Curve; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Germany; Humans; Hydroxylation; Hypericum; Ketoconazole; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Plant Extracts; Plants, Medicinal; Pregnane X Receptor; Receptors, Steroid; Substrate Specificity; Transcription, Genetic; Young Adult

2013

Other Studies

1 other study(ies) available for ketoconazole and hypericum

ArticleYear
In vitro CYP3A4 metabolism: inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:5

    Topics: Binding Sites; Coumarins; Cytochrome P-450 CYP3A; Echinacea; Enzyme Inhibitors; Herb-Drug Interactions; Humans; Hypericum; Inhibitory Concentration 50; Ketoconazole; Plant Extracts; Quinolines; Testosterone

2008