Compounds > ketoconazole

ketoconazole and heme

ketoconazole has been researched along with heme in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (33.33)	18.2507
2000's	3 (50.00)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aoki, Y; Arisawa, M; Kondoh, M; Nakamura, Y; Nakayama, N; Yoshihara, F	1
Barbuch, R; Bard, M; Gachotte, D; Koegel, C; Lees, ND; Pierson, CA	1
Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Serada, S; Tajima, K; Takano, R	1
Ahmed, S	1
Hori, H; Kawaguchi, Y; Masubuchi, Y; Ohkura, K; Shinohara, Y; Watanabe, Y	1
Poulos, TL; Sevrioukova, IF	1

Other Studies

6 other study(ies) available for ketoconazole and heme

Article	Year
Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:12 Topics: Animals; Antifungal Agents; Carbon Monoxide; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluconazole; Fungal Proteins; Glycine; Heme; Ketoconazole; Liver; Male; Microsomes, Liver; Oxidoreductases; Pyrans; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae; Sensitivity and Specificity; Sterol 14-Demethylase	1993
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme. Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21 Topics: Antifungal Agents; Azoles; Clotrimazole; Genes, Fungal; Genotype; Heme; Itraconazole; Ketoconazole; Lanosterol; Mixed Function Oxygenases; Mutation; Saccharomyces cerevisiae; Sterols; Suppression, Genetic	1997
Effect of antifungal azoles on the heme detoxification system of malarial parasite. Journal of biochemistry, 2002, Volume: 131, Issue:3 Topics: Animals; Antifungal Agents; Antimalarials; Clotrimazole; Electron Spin Resonance Spectroscopy; Erythrocytes; Glutathione; Heme; Hemolysis; Humans; In Vitro Techniques; Ketoconazole; Miconazole; Peptides; Plasmodium falciparum; Spectrum Analysis	2002
The use of the novel substrate-heme complex approach in the derivation of a representation of the active site of the enzyme complex 17alpha-hydroxylase and 17,20-lyase. Biochemical and biophysical research communications, 2004, Apr-09, Volume: 316, Issue:3 Topics: Antineoplastic Agents; Binding Sites; Biochemistry; Heme; Hydrogen; Hydrogen Bonding; Ketoconazole; Miconazole; Models, Chemical; Models, Molecular; Oxygen; Steroid 17-alpha-Hydroxylase; Steroids	2004
Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. Anticancer research, 2009, Volume: 29, Issue:3 Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Erythromycin; Heme; Humans; Ketoconazole; Ligands; Metyrapone; Models, Molecular; Molecular Sequence Data; Progesterone; Protein Binding; Protein Conformation; Static Electricity; Substrate Specificity	2009
Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir. Proceedings of the National Academy of Sciences of the United States of America, 2010, Oct-26, Volume: 107, Issue:43 Topics: Binding Sites; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Heme; HIV Infections; HIV Protease Inhibitors; Humans; In Vitro Techniques; Ketoconazole; Kinetics; Ligands; Macromolecular Substances; Models, Molecular; Molecular Structure; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Ritonavir; Spectrophotometry	2010