Compounds > ketoconazole

ketoconazole and guaifenesin

ketoconazole has been researched along with guaifenesin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Breäs, R; Crommelin, DJ; Poelma, FG; Tukker, JJ1
Cassano, R; Ferrarelli, T; Schätzlein, AG; Trombino, S; Uchegbu, IF1

Reviews

1 review(s) available for ketoconazole and guaifenesin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for ketoconazole and guaifenesin

ArticleYear
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Intestinal absorption of drugs. The influence of mixed micelles on on the disappearance kinetics of drugs from the small intestine of the rat.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:5

    Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Dantrolene; Griseofulvin; Intestinal Absorption; Intestine, Small; Ketoconazole; Kinetics; Lysophosphatidylcholines; Micelles; Models, Biological; Mucus; Rats; Solubility; Swine; Taurocholic Acid; Theophylline

1991
Dextran-pegylated microparticles for enhanced cellular uptake of hydrophobic drugs.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 84, Issue:3

    Topics: Caco-2 Cells; Cell Line; Dextrans; Drug Carriers; Drug Design; HT29 Cells; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Ketoconazole; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Mucus; Polyethylene Glycols; Polymers; Spectroscopy, Fourier Transform Infrared; Time Factors; Water

2013