ketoconazole and glycine

ketoconazole has been researched along with glycine in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (12.50)	18.7374
1990's	1 (12.50)	18.2507
2000's	2 (25.00)	29.6817
2010's	3 (37.50)	24.3611
2020's	1 (12.50)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Retico, A; Simonetti, N; Villa, A	1
Aoki, Y; Arisawa, M; Kondoh, M; Nakamura, Y; Nakayama, N; Yoshihara, F	1
Bacic, A; Callaghan, JM; Currie, G; Ferguson, K; McConville, MJ; McFadden, GI; Naderer, T; Spurck, T; Tull, D; Vince, JE	1
Bessudo, A; Esseltine, DL; Gupta, N; Hanley, MJ; Ke, A; Liu, G; Nemunaitis, J; O'Neil, BH; Patel, C; Rasco, DW; Rowland Yeo, K; Sharma, S; Venkatakrishnan, K; Wang, B; Xia, C; Zhang, X	1
Fan, B; Ke, A; Le, K; Prakash, C; Yang, H	1

Trials

1 trial(s) available for ketoconazole and glycine

Article	Year
Effects of Strong CYP3A Inhibition and Induction on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor: Results of Drug-Drug Interaction Studies in Patients With Advanced Solid Tumors or Lymphoma and a Physiologically Based Pharmacokinetic Ana Journal of clinical pharmacology, 2018, Volume: 58, Issue:2 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Boron Compounds; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Glycine; Humans; Ketoconazole; Male; Middle Aged; Models, Biological; Neoplasms; Proteasome Inhibitors; Rifampin	2018

Article

Year

Effects of Strong CYP3A Inhibition and Induction on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor: Results of Drug-Drug Interaction Studies in Patients With Advanced Solid Tumors or Lymphoma and a Physiologically Based Pharmacokinetic Ana

Journal of clinical pharmacology, 2018, Volume: 58, Issue:2

Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Boron Compounds; Clarithromycin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Glycine; Humans; Ketoconazole; Male; Middle Aged; Models, Biological; Neoplasms; Proteasome Inhibitors; Rifampin

2018

Other Studies

7 other study(ies) available for ketoconazole and glycine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Action of the ketoconazole-alkylaminoethylglycine combination on Candida albicans. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:6 Topics: Candida albicans; Cell Membrane Permeability; Drug Combinations; Glycine; Ketoconazole	1989
Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:12 Topics: Animals; Antifungal Agents; Carbon Monoxide; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluconazole; Fungal Proteins; Glycine; Heme; Ketoconazole; Liver; Male; Microsomes, Liver; Oxidoreductases; Pyrans; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae; Sensitivity and Specificity; Sterol 14-Demethylase	1993
SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane in Leishmania. Molecular biology of the cell, 2004, Volume: 15, Issue:11 Topics: Amino Acid Sequence; Animals; Cell Membrane; Cloning, Molecular; Cysteine; Cytoskeleton; Detergents; Epitopes; Fatty Acids; Fatty Acids, Monounsaturated; Flagella; Glycine; Immunoblotting; Ketoconazole; Kinetoplastida; Leishmania major; Lipid Metabolism; Membrane Proteins; Microscopy, Electron; Microscopy, Fluorescence; Molecular Sequence Data; Myristic Acid; Octoxynol; Palmitic Acid; Phylogeny; Polyethylene Glycols; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sphingolipids; Temperature; Tubulin	2004
Physiologically based pharmacokinetic modeling and simulation to predict drug-drug interactions of ivosidenib with CYP3A perpetrators in patients with acute myeloid leukemia. Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:5 Topics: Administration, Oral; Antineoplastic Agents; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fluconazole; Glycine; Healthy Volunteers; Humans; Itraconazole; Ketoconazole; Leukemia, Myeloid, Acute; Male; Microsomes, Liver; Models, Biological; Pyridines; Rifampin	2020