ketoconazole has been researched along with finasteride in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 12 (42.86) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez-Manrique, B; Bratoeff, E; Cabeza, M; Cortés-Benítez, F; Ramírez-Apan, MT | 1 |
| Brodie, AM; Grigoryev, DN; Kato, K; Long, BJ; Njar, VC; Nnane, IP | 1 |
| Ehmer, PB; Haidar, S; Hartmann, RW; Hector, M; Jose, J; Reichert, W | 1 |
| Brodie, AM; Chopra, P; Farquhar, R; Gediya, LK; Guo, Z; Handratta, VD; Kataria, R; Newman, D; Njar, VC; Qiu, Y; Vasaitis, TS | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bondesson, U; Hedeland, M; Lennernäs, H; Lundahl, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Bratoeff, E; Cabeza, M; Garrido, M; Heuze, Y; Ramírez-Apan, T; Sánchez, A; Soriano, J | 1 |
| Bratoeff, E; Cabeza, M; Heuze, Y; Ramírez-Apan, T; Sánchez, A; Silva-Ortiz, AV; Soriano, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Carpenter, PC; Turk, DM | 1 |
| Shaw, JC | 1 |
| Brodie, A; Kato, K; Ling, YZ; Liu, Y; Lu, Q; Nnane, IP; Wang, X | 1 |
| Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S | 1 |
| Carney, EW; Crissman, JW; Marty, MS | 2 |
| Brodie, AM; Grigoryev, DN; Ling, YZ; Liu, Y; Long, BJ; Nnane, IP | 1 |
| Khandpur, S; Reddy, BS; Suman, M | 1 |
| Hugo Perez, BS | 1 |
| Haber, RS | 1 |
| Tsiskarishvili, NV; Tsiskarishvili, TsI | 1 |
| Avram, MR; Rogers, NE | 1 |
| Adomat, HH; Gleave, ME; Guns, ES; Hendy, SC; Locke, JA; Nelson, CC | 1 |
| Ioannides, D; Lazaridou, E | 1 |
5 review(s) available for ketoconazole and finasteride
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antiandrogen therapy in dermatology.
Topics: Adrenal Cortex Hormones; Androgen Antagonists; Cimetidine; Contraceptives, Oral; Cyproterone Acetate; Finasteride; Flutamide; Humans; Ketoconazole; Skin Diseases; Spironolactone | 1996 |
Pharmacologic management of pattern hair loss.
Topics: Administration, Topical; Alopecia; Androgen Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Finasteride; Humans; Ketoconazole; Male; Minoxidil; Treatment Outcome | 2004 |
Medical treatments for male and female pattern hair loss.
Topics: Adult; Alopecia; Androgen Antagonists; Azasteroids; Drug Therapy, Combination; Dutasteride; Female; Finasteride; Hair; Humans; Hyperhidrosis; Ketoconazole; Male; Minoxidil; Phototherapy; Prostate; Sperm Count; Tretinoin | 2008 |
Female pattern hair loss.
Topics: 5-alpha Reductase Inhibitors; Administration, Cutaneous; Alopecia; Androgen Antagonists; Androgen Receptor Antagonists; Antifungal Agents; Cyproterone Acetate; Dutasteride; Female; Finasteride; Flutamide; Hair; Humans; Ketoconazole; Minoxidil; Postmenopause; Spironolactone; Vasodilator Agents | 2015 |
3 trial(s) available for ketoconazole and finasteride
| Article | Year |
|---|---|
A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism.
Topics: Adult; Cyproterone Acetate; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Hormones; Humans; Ketoconazole; Prospective Studies | 1999 |
Comparative efficacy of various treatment regimens for androgenetic alopecia in men.
Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Administration, Topical; Adolescent; Adult; Alopecia; Drug Therapy, Combination; Enzyme Inhibitors; Finasteride; Hair Preparations; Humans; Ketoconazole; Male; Minoxidil | 2002 |
[Effectiveness of the treatment plan for androgenetic alopecia].
Topics: Adolescent; Adult; Alopecia; Antifungal Agents; Chronic Disease; Enzyme Inhibitors; Female; Finasteride; Humans; Ketoconazole; Male; Middle Aged; Minoxidil; Vasodilator Agents; Zinc | 2007 |
20 other study(ies) available for ketoconazole and finasteride
| Article | Year |
|---|---|
Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line.
Topics: Androgens; Androstenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Humans; Leukocytes, Mononuclear; Male; Prostatic Neoplasms; Rats | 2016 |
Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Male; Microsomes; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Testis; Triazoles; Tumor Cells, Cultured | 1998 |
Synthesis and evaluation of novel steroidal oxime inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase) and 5 alpha-reductase types 1 and 2.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Cell Line; Enzyme Inhibitors; Escherichia coli; Humans; Male; Microsomes; Oximes; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Testis; Testosterone | 2000 |
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Azoles; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Humans; Isoenzymes; Male; Mice; Mice, SCID; Mutation; Prostatic Neoplasms; Pyrazines; Radioligand Assay; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Tissue Distribution; Transcription, Genetic; Transcriptional Activation; Xenograft Model Antitumor Assays | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
In vivo investigation in pigs of intestinal absorption, hepatobiliary disposition, and metabolism of the 5α-reductase inhibitor finasteride and the effects of coadministered ketoconazole.
Topics: 14-alpha Demethylase Inhibitors; 5-alpha Reductase Inhibitors; Animals; Bile; Drug Interactions; Finasteride; Half-Life; Injections, Intravenous; Intestinal Absorption; Ketoconazole; Liver; Male; Prostatic Neoplasms; Swine | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Effect of dehydroepiandrosterone derivatives on the activity of 5α-reductase isoenzymes and on cancer cell line PC-3.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Cholestenone 5 alpha-Reductase; Cricetinae; Dehydroepiandrosterone; Female; Humans; Isoenzymes; Male; Mice; Middle Aged; Prostate; Prostatic Neoplasms; Rats | 2014 |
Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5α-reductase and on cancer cell line SK-LU-1.
Topics: 5-alpha Reductase Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cholestenone 5 alpha-Reductase; Humans; Male; Mesocricetus; Neoplasms; Pregnenolone; Rats | 2015 |
Hirsutism.
Topics: Androgen Antagonists; Bromocriptine; Contraceptives, Oral, Combined; Dexamethasone; Female; Finasteride; Goserelin; Hirsutism; Humans; Ketoconazole; Leuprolide; Medroxyprogesterone Acetate; Nafarelin | 1994 |
Effects of some novel inhibitors of C17,20-lyase and 5alpha-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer.
Topics: Androgens; Animals; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Humans; Ketoconazole; Male; Organ Size; Oxidoreductases; Prostate; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Testosterone | 1998 |
Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta-estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor.
Topics: 5-alpha Reductase Inhibitors; Animals; Antineoplastic Agents, Hormonal; Antithyroid Agents; Endocrine Glands; Enzyme Inhibitors; Estradiol; Evaluation Studies as Topic; Fadrozole; Female; Finasteride; Ketoconazole; Male; Organ Size; Propylthiouracil; Rats; Rats, Inbred Strains; Sexual Maturation; Steroids; Testolactone; Thyroid Hormones; Toxicology; Uterus; Weight Gain | 1999 |
Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgen Receptor Antagonists; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Cell Division; Chlorocebus aethiops; Finasteride; Growth Inhibitors; Humans; Ketoconazole; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms, Hormone-Dependent; Oleanolic Acid; Pregnadienes; Prostatic Neoplasms; Receptors, Androgen; Saponins; Steroid 17-alpha-Hydroxylase; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2000 |
Evaluation of the male pubertal onset assay to detect testosterone and steroid biosynthesis inhibitors in CD rats.
Topics: Animals; Body Weight; Dihydrotestosterone; Fadrozole; Finasteride; Genitalia, Male; Hormone Antagonists; Ketoconazole; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sexual Maturation; Testolactone; Testosterone; Thyroid Gland; Toxicity Tests; Weaning | 2001 |
Ketocazole as an adjunct to finasteride in the treatment of androgenetic alopecia in men.
Topics: Administration, Oral; Administration, Topical; Alopecia; Antifungal Agents; Chemotherapy, Adjuvant; Clinical Trials as Topic; Drug Therapy, Combination; Enzyme Inhibitors; Evidence-Based Medicine; Finasteride; Hair Preparations; Humans; Ketoconazole; Male; Treatment Outcome | 2004 |
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts.
Topics: Androgen Antagonists; Androgens; Anilides; Animals; Castration; Cell Line, Tumor; Cinnamates; Disease Progression; Drug Combinations; Enzyme Inhibitors; Finasteride; Gene Expression Regulation, Neoplastic; Humans; Ketoconazole; Male; Mice; Mice, Nude; Mifepristone; Molecular Structure; Neoplasm Transplantation; Nitriles; Progesterone; Prostatic Neoplasms; Steroids; Tosyl Compounds; Transplantation, Heterologous | 2009 |