ketoconazole has been researched along with etomidate in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 14 (45.16) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Berger, ML; Hahner, S; Hammerschmidt, F; Peric-Simov, B; Schirbel, A; Zolle, IM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Hartmann, RW; Hu, Q; Yin, L | 1 |
| Hartmann, RW; Hille, UE; Vock, CA; Zimmer, C | 1 |
| Hartmann, RW; Haupenthal, J; Hille, UE; Zimmer, C | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bons, EG; Bruining, HA; de Jong, FH; Lamberts, SW | 1 |
| Nonaka, Y; Ohnishi, T; Okamoto, M; Wada, A | 1 |
| Feldman, D | 1 |
| Lamberts, SW | 1 |
| Katagiri, M; Miyamori, I; Nagai, K; Suhara, K; Takeda, R | 1 |
| Engelhardt, D | 1 |
| Engelhardt, D; Weber, MM | 1 |
| Abedinpour, F; Adelmann, B; Engelhardt, D; Lang, J; Weber, MM; Zeilberger, K | 1 |
| Broadbear, JH; Winger, G; Woods, JH | 1 |
| Brain, CE; Greening, JE; Grossman, AB; Mushtaq, I; Perry, LA; Sales Marques, J; Savage, MO | 1 |
| Dabbagh, A; Heidari, Z; Sa'adat, N | 1 |
| de Herder, WW; Feelders, RA; Hofland, LJ | 1 |
| Cáp, J; Cerman, J; Gabalec, F; Havel, E; Radocha, J; Svilias, I; Zavrelová, A | 1 |
| Biller, BM; Tritos, NA | 1 |
| Barahona Constanzo, MJ; del Pozo Picó, C | 1 |
| Daniel, E; Newell-Price, JD | 1 |
| Alexandraki, KI; Grossman, AB | 1 |
| Biller, BMK; Tritos, NA | 1 |
| Tritos, NA | 1 |
| Fleseriu, M; Han, AJ; Varlamov, EV | 1 |
| Hull, B; Wedrychowicz, A | 1 |
13 review(s) available for ketoconazole and etomidate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Ketoconazole and other imidazole derivatives as inhibitors of steroidogenesis.
Topics: Adrenal Cortex Hormones; Animals; Cytochrome P-450 Enzyme Inhibitors; Etomidate; Gonadal Steroid Hormones; Humans; Imidazoles; Ketoconazole; Steroids | 1986 |
Steroid biosynthesis inhibitors in Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane | 1994 |
Therapy of Cushing's syndrome with steroid biosynthesis inhibitors.
Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans; Ketoconazole; Metyrapone; Steroids | 1994 |
Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole.
Topics: Cushing Syndrome; Enzyme Inhibitors; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane | 2010 |
Advances in medical therapies for Cushing's syndrome.
Topics: Animals; Bexarotene; Cushing Syndrome; Etomidate; Humans; Ketoconazole; Lapatinib; Metyrapone; Mifepristone; Mitotane; Quinazolines; Somatostatin; Tetrahydronaphthalenes | 2012 |
New prospects for drug treatment in Cushing disease.
Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Ergolines; Etomidate; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Metyrapone; Mice; Mifepristone; Mitotane; Multicenter Studies as Topic; Pituitary ACTH Hypersecretion; Pituitary Neoplasms; PPAR gamma; Pyridines; Rats; Somatostatin; Therapies, Investigational; Tretinoin | 2012 |
Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome.
Topics: Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Pyridines; Steroid Synthesis Inhibitors | 2015 |
Therapeutic Strategies for the Treatment of Severe Cushing's Syndrome.
Topics: Animals; Cushing Syndrome; Etomidate; Humans; Hydrocortisone; Ketoconazole; Metyrapone | 2016 |
Medical Management of Cushing Disease.
Topics: Cabergoline; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin; Temozolomide; Treatment Outcome | 2019 |
Adrenally Directed Medical Therapies for Cushing Syndrome.
Topics: Adrenal Glands; Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Molecular Targeted Therapy; Pyridines | 2021 |
Updates in adrenal steroidogenesis inhibitors for Cushing's syndrome - A practical guide.
Topics: Cushing Syndrome; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Etomidate; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Metyrapone; Pituitary ACTH Hypersecretion; Practice Patterns, Physicians'; Pyridines; Steroids | 2021 |
The function of adrenal glands in children and adolescents during and after oncological treatment.
Topics: Adolescent; Adrenal Glands; Child; Etomidate; Fluconazole; Humans; Hypothalamo-Hypophyseal System; Immune Checkpoint Inhibitors; Ketoconazole; Metyrapone; Mitotane; Pituitary-Adrenal System; Quality of Life | 2022 |
18 other study(ies) available for ketoconazole and etomidate
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
Topics: Adrenal Cortex; Animals; Binding Sites; Etomidate; Humans; Hydroxylation; Iodine Radioisotopes; Kinetics; Male; Molecular Structure; Rats; Rats, Wistar; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases.
Topics: Aldosterone; Animals; Benzimidazoles; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Fadrozole; Humans; Indans; Indoles; Kidney Diseases; Mineralocorticoids; Naphthalenes; Quinolines; Receptors, Mineralocorticoid | 2014 |
First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases.
Topics: | 2011 |
Optimization of the First Selective Steroid-11β-hydroxylase (CYP11B1) Inhibitors for the Treatment of Cortisol Dependent Diseases.
Topics: | 2011 |
Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenocorticotropic Hormone; Cortodoxone; Cushing Syndrome; Etomidate; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Ketoconazole; Metyrapone; Miconazole; Progesterone | 1987 |
Inhibition of bovine adrenocortical mitochondrial cytochrome P-450(11)beta-mediated reactions by imidazole derivatives and mineralocorticoid analogs.
Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Clotrimazole; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Etomidate; Imidazoles; Ketoconazole; Miconazole; Mineralocorticoids; Mitochondria | 1988 |
[Adrenal cortex insufficiency caused by drugs].
Topics: Adrenal Insufficiency; Etomidate; Humans; Ketoconazole | 1987 |
Effect of ketoconazole, etomidate and other inhibitors of steroidogenesis on cytochrome P-450sccII-catalyzed reactions.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Etomidate; Ketoconazole; Kinetics; Male; Steroids; Swine; Testis | 1987 |
Different inhibitory effect of etomidate and ketoconazole on the human adrenal steroid biosynthesis.
Topics: Adrenal Glands; Aldehyde-Lyases; Androgens; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme Inhibitors; Etomidate; Humans; In Vitro Techniques; Ketoconazole; Steroid 11-beta-Hydroxylase; Steroid 16-alpha-Hydroxylase; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases | 1993 |
Cocaine-reinforced responding in rhesus monkeys: pharmacological attenuation of the hypothalamic-pituitary-adrenal axis response.
Topics: Animals; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Etomidate; Glucocorticoids; Hypnotics and Sedatives; Hypothalamo-Hypophyseal System; Ketoconazole; Macaca mulatta; Male; Neuroprotective Agents; Peptide Fragments; Pituitary-Adrenal System; Reinforcement, Psychology | 1999 |
Efficient short-term control of hypercortisolaemia by low-dose etomidate in severe paediatric Cushing's disease.
Topics: Adrenalectomy; Child; Contraindications; Cushing Syndrome; Etomidate; Humans; Hydrocortisone; Ketoconazole; Male; Metyrapone | 2005 |
Etomidate infusion in the critical care setting for suppressing the acute phase of Cushing's syndrome.
Topics: Acute Disease; Administration, Oral; Adolescent; Adrenalectomy; Critical Care; Cushing Syndrome; Enzyme Inhibitors; Etomidate; Female; Humans; Hydrocortisone; Infusions, Intravenous; Ketoconazole; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Treatment Outcome | 2009 |
Pneumocystis pneumonia during medicamentous treatment of Cushing's syndrome--a description of two cases.
Topics: Adult; Cushing Syndrome; Etomidate; Female; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Opportunistic Infections; Pneumonia, Pneumocystis; Young Adult | 2011 |