ketoconazole and ergosterol

ketoconazole has been researched along with ergosterol in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199018 (34.62)18.7374
1990's17 (32.69)18.2507
2000's9 (17.31)29.6817
2010's7 (13.46)24.3611
2020's1 (1.92)2.80

Authors

AuthorsStudies
Cannon, RD; Holmes, AR; Lamping, E; Nakamura, K; Niimi, K; Niimi, M; Ranchod, A; Tyndall, JD1
Arnstein, HR; Cannon, M; Halliwell, B; Smith, C; Wiseman, H1
de Souza, W; Lazardi, K; Urbina, JA2
Ballard, SA; Ellis, SW; Kelly, SL; Troke, PF1
Howell, SA; Mallet, AI; Noble, WC1
Kozený, M; Latinák, J; Lenhart, K; Merkunová, A; Walterová, D2
Hart, DT; Lauwers, WJ; Opperdoes, FR; Vanden Bossche, H; Willemsens, G1
Kerridge, D; Nicholas, RO1
Geerts, H; Gorrens, J; Janssen, PA; Marichal, P; Vanden Bossche, H1
Rippon, JW1
Kelly, SL; Rose, ME; Watson, PF1
Dix, BA; Freudenberger, J; Funke, PT; Georgopapadakou, NH; Smith, SA1
Gorman, SP; McGrath, SJ; Scott, EM1
Ryder, NS1
Cools, W; Cornelissen, F; Lauwers, WF; van Cutsem, JM; Van den Bossche, H; Willemsens, G1
Borgers, M; Negroni de Bonvehi, MB; Negroni, R1
Feingold, DS; Sud, IJ2
Borgers, M; De Brabander, M; Van den Bossche, H1
Bolard, J; Brajtburg, J; Kobayashi, GS; Medoff, G1
Johnson, EM; Richardson, MD; Warnock, DW1
Barrett-Bee, KJ; Ryley, JF; Wilson, RG1
Brasini, S; De Luca, C; Fabbri, AA; Fanelli, C; Passi, S1
Baldwin, BC; Corran, A; Kelly, SL; Kwon-Chung, J; Lamb, DC1
Lenhart, K; Merkunová, A1
Bartlett, MS; Queener, SF; Richardson, JD; Shaw, MM; Smith, JW1
Bolard, J; Cohen, BE; Ramos, H; Saint-Pierre-Chazalet, M1
Arnoldi, A; Kelly, DE; Kelly, SL; Kenna, S1
Hiratani, T; Yamaguchi, H1
Maldonado, RA; Molina, J; Payares, G; Urbina, JA1
Bonaly, R; Coulon, J; Harmouch, N1
Crowley, JH; Parks, LW; Smith, SJ1
Baldwin, BC; Corran, AJ; Kelly, DE; Kelly, SL; Lamb, DC1
Hinnen, A; Launhardt, H; Munder, T1
Fuchsbichler, S; Leber, R; Pühringer, B; Schröttner, K; Turnowsky, F; Zenz, R1
Daneshtalab, M; Kurosawa, T; Mori, Y; Sardari, S1
Konopka, JB; Martin, SW1
Barbosa, HS; de Castro, SL; Lira, R; Santa-Rita, RM; Urbina, JA1
Almeida, D; de Nazareth S L de Meirelles, M; Pereira, MC; Silva, DT; Urbina, JA1
Cabezas-Herrera, J; Navarro-Martínez, MD; Rodríguez-López, JN1
Khan, NA; Matin, A; Siddiqui, R; Stins, M; Warhurst, D1
Li, Y; Tang, Q; Yuan, QP1
Cummings, ED; Hilliard, GM; Hoehamer, CF; Rogers, PD1
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M1
Butler, G; Guida, A; Higgins, DG; Mulhern-Haughey, S; Synnott, JM1
Duan, CQ; Wen, KR; Yan, GL1
Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AG1
Balamurugan, K; Iyer, PM; Pandian, SK; Subramenium, GA; Swetha, TK1
Balliano, G; Bianchi, MM; Cirigliano, A; Macone, A; Negri, R; Oliaro-Bosso, S; Rinaldi, T1
Burleigh, B; Dumoulin, PC; Tomko, SS; Vollrath, J; Wang, JX1

Reviews

2 review(s) available for ketoconazole and ergosterol

ArticleYear
The mechanism of action of the new antimycotic ketoconazole.
    The American journal of medicine, 1983, Jan-24, Volume: 74, Issue:1B

    Topics: Animals; Antifungal Agents; Candida albicans; Cell Membrane Permeability; Culture Media; Ergosterol; Fatty Acids; Fungi; Humans; Imidazoles; Ketoconazole; Phagocytes; Phospholipids; Piperazines; Rats; Sterols; Triglycerides

1983
Antifungal agents useful in therapy of systemic fungal infections.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Amphotericin B; Animals; Antifungal Agents; Binding, Competitive; Cholesterol; Ergosterol; Flucytosine; Fungi; Humans; Imidazoles; Ketoconazole; Membranes, Artificial; Miconazole; Mycoses; Phospholipids; Piperazines; Sterols

1983

Other Studies

50 other study(ies) available for ketoconazole and ergosterol

ArticleYear
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Blotting, Northern; Blotting, Southern; Candida; Candidiasis; Cell Membrane; Chromosomes, Fungal; Drug Resistance, Fungal; Endoplasmic Reticulum; Humans; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae

2009
The antioxidant action of ketoconazole and related azoles: comparison with tamoxifen and cholesterol.
    Chemico-biological interactions, 1991, Volume: 79, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Cattle; Cholesterol; Ergosterol; Estrogen Antagonists; Ferric Compounds; Iron; Ketoconazole; Lipid Peroxidation; Liposomes; Male; Microsomes, Liver; Phospholipids; Rats; Stilbenes; Tamoxifen

1991
Ultrastructural alterations induced by ICI 195,739, a bis-triazole derivative with strong antiproliferative action against Trypanosoma (Schizotrypanum) cruzi.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4

    Topics: Animals; Ergosterol; Ketoconazole; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells

1991
Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:11

    Topics: Animals; Ergosterol; Ketoconazole; Microscopy, Electron; Naphthalenes; Terbinafine; Trypanocidal Agents; Trypanosoma cruzi

1990
A novel method for studying ergosterol biosynthesis by a cell-free preparation of Aspergillus fumigatus and its inhibition by azole antifungal agents.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1990, Volume: 28, Issue:4

    Topics: Antifungal Agents; Aspergillus fumigatus; Autoradiography; Azoles; Chromatography, Thin Layer; Ergosterol; Fluconazole; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Molecular Structure

1990
A comparison of the sterol content of multiple isolates of the Candida albicans Darlington strain with other clinically azole-sensitive and -resistant strains.
    The Journal of applied bacteriology, 1990, Volume: 69, Issue:5

    Topics: Azoles; Candida albicans; Drug Resistance, Microbial; Ergosterol; Gas Chromatography-Mass Spectrometry; Humans; Ketoconazole; Sterols

1990
Ketoconazole-resistant mutants of Microsporum gypseum. I. Isolation of mutants, biochemical methods.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1989, Volume: 122

    Topics: Drug Resistance, Microbial; Ergosterol; Ketoconazole; Microsporum; Mutation

1989
Ketoconazole-resistant mutants of Microsporum gypseum. II. Characteristics of mutants.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1989, Volume: 122

    Topics: Clotrimazole; Drug Resistance, Microbial; Ergosterol; Ketoconazole; Miconazole; Microsporum; Mutation

1989
Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages.
    Molecular and biochemical parasitology, 1989, Mar-01, Volume: 33, Issue:2

    Topics: Acetates; Animals; Antiprotozoal Agents; Cell Division; Cell Line; Cholesterol; Ergosterol; Itraconazole; Ketoconazole; Leishmania mexicana; Macrophages; Sterols

1989
Correlation of inhibition of sterol synthesis with growth-inhibitory action of imidazole antimycotics in Candida albicans.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23, Issue:1

    Topics: Antifungal Agents; Candida albicans; Ergosterol; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Staphylococcus aureus; Sterols

1989
Mode of action studies. Basis for the search of new antifungal drugs.
    Annals of the New York Academy of Sciences, 1988, Volume: 544

    Topics: Acetates; Antifungal Agents; Candida; Candida albicans; Cytochrome P-450 Enzyme System; Drug Design; Ergosterol; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Microsomes

1988
A new era in antimycotic agents.
    Archives of dermatology, 1986, Volume: 122, Issue:4

    Topics: Animals; Antifungal Agents; Azoles; Candida albicans; Chitin; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Dogs; Ergosterol; Fungi; Humans; Itraconazole; Ketoconazole; Lanosterol; Liver; Rats; Sterols

1986
Isolation and analysis of ketoconazole resistant mutants of Saccharomyces cerevisiae.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1988, Volume: 26, Issue:3

    Topics: Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Ergosterol; Gas Chromatography-Mass Spectrometry; Genetic Complementation Test; Ketoconazole; Microbial Sensitivity Tests; Mutation; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet

1988
Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1

    Topics: Allylamine; Animals; Antifungal Agents; Candida albicans; Cell Membrane; Cerulenin; Cholestadienols; Chromatography, Gas; Chromatography, Thin Layer; Clotrimazole; Culture Techniques; Econazole; Ergosterol; Fatty Acids; Ketoconazole; Lipids; Miconazole; Tolnaftate

1987
Inhibition of hyphal development in Trichophyton mentagrophytes arthroconidia by ketoconazole and miconazole.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 15, Issue:4

    Topics: Ergosterol; Ketoconazole; Miconazole; Trichophyton

1985
Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:2

    Topics: Allylamine; Animals; Antifungal Agents; Candida; Cell-Free System; Cholesterol; Ergosterol; Hydrogen-Ion Concentration; In Vitro Techniques; Ketoconazole; Liver; Male; Mevalonic Acid; Naphthalenes; Rats; Squalene; Sterols; Terbinafine; Trichophyton

1985
In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:6

    Topics: Animals; Antifungal Agents; Candida albicans; Cell Membrane; Cholesterol; Culture Media; Dose-Response Relationship, Drug; Ergosterol; Female; Imidazoles; Ketoconazole; Lanosterol; Piperazines; Rats; Sterols; Time Factors

1980
Ultrastructural changes produced by ketoconazole in the yeast-like phase of Paracoccidioides brasiliensis and Histoplasma capsulatum.
    Mycopathologia, 1981, May-08, Volume: 74, Issue:2

    Topics: Cell Membrane; Cytoplasm; Ergosterol; Fungi; Histoplasma; Imidazoles; Ketoconazole; Microscopy, Electron; Morphogenesis; Paracoccidioides; Phospholipids; Piperazines; Triglycerides

1981
Heterogeneity of action of mechanisms among antimycotic imidazoles.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Antifungal Agents; Clotrimazole; Ergosterol; Imidazoles; Ketoconazole; Lanosterol; Miconazole; Piperazines; Saccharomyces cerevisiae

1981
Effect of ketoconazole on the fungicidal action of amphotericin B in Candida albicans.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1

    Topics: Amphotericin B; Antifungal Agents; Candida albicans; Drug Interactions; Ergosterol; Imidazoles; Ketoconazole; Piperazines

1983
Effect of imidazole antifungals on the development of germ tubes by strains of Candida albicans.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:4

    Topics: Antifungal Agents; Candida albicans; Ergosterol; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests

1983
Azole resistance in Candida albicans.
    Sabouraudia, 1984, Volume: 22, Issue:1

    Topics: Amino Acids; Animals; Antifungal Agents; Candida albicans; Candidiasis, Chronic Mucocutaneous; Candidiasis, Vulvovaginal; Drug Resistance, Microbial; Ergosterol; Female; Ketoconazole; Mice; Rats; Triazoles

1984
Effect of different inhibitors of sterol biosynthesis on both fungal growth and aflatoxin production.
    Natural toxins, 1995, Volume: 3, Issue:2

    Topics: Aflatoxins; Antifungal Agents; Aspergillus; Culture Media; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Econazole; Ergosterol; Fatty Acids; Itraconazole; Ketoconazole; Miconazole

1995
Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients.
    FEBS letters, 1995, Jul-17, Volume: 368, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cryptococcosis; Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Drug Tolerance; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Microsomes; Oxidoreductases; Sterol 14-Demethylase; Sterols; Treatment Failure

1995
Effect of ketoconazole on potassium pool, c-AMP-release and ergosterol synthesis in resistant mutants of Microsporum gypseum.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1994, Volume: 137

    Topics: Cyclic AMP; Drug Resistance, Microbial; Ergosterol; Ketoconazole; Microsporum; Mutation; Potassium

1994
Pneumocystis carinii is resistant to imidazole antifungal agents.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8

    Topics: Animals; Antifungal Agents; Ergosterol; Female; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Miconazole; Pneumocystis; Rats; Rats, Sprague-Dawley; Triazoles

1994
Effect of ketoconazole on lethal action of amphotericin B on Leishmania mexicana promastigotes.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:5

    Topics: Amphotericin B; Animals; Cell Membrane; Diphenylhexatriene; Ergosterol; Fluorescent Dyes; Ketoconazole; Kinetics; Leishmania mexicana; Nitrates; Potassium Compounds; Spectrometry, Fluorescence; Sterols; Temperature

1994
Studies on azole-induced cell death in Saccharomyces cerevisiae.
    FEMS microbiology letters, 1994, Jan-15, Volume: 115, Issue:2-3

    Topics: Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ergosterol; Ketoconazole; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Species Specificity; Sterols

1994
[Cross-resistance of Candida albicans to several different families of antifungals with ergosterol biosynthesis-inhibiting activity].
    The Japanese journal of antibiotics, 1994, Volume: 47, Issue:2

    Topics: Antifungal Agents; Candida albicans; Depression, Chemical; Drug Resistance, Microbial; Ergosterol; Ketoconazole; Morpholines; Naphthalenes; Terbinafine; Triazoles

1994
Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:6

    Topics: Animals; Antifungal Agents; Chagas Disease; Disease Models, Animal; Ergosterol; Female; Ketoconazole; Mice; Naphthalenes; Terbinafine; Triazoles; Trypanocidal Agents

1993
Identification of 24-methylene-24,25-dihydrolanosterol as a precursor of ergosterol in the yeasts Schizosaccharomyces pombe and Schizosaccharomyces octosporus.
    FEMS microbiology letters, 1995, Dec-15, Volume: 134, Issue:2-3

    Topics: Binding Sites; Cell Membrane; Ergosterol; Ketoconazole; Lanosterol; Methylation; Schizosaccharomyces; Species Specificity; Sterols

1995
Transcriptional regulation by ergosterol in the yeast Saccharomyces cerevisiae.
    Molecular and cellular biology, 1996, Volume: 16, Issue:10

    Topics: Aerobiosis; beta-Galactosidase; Ergosterol; Fungicides, Industrial; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Reporter; Genotype; Ketoconazole; Lac Operon; Lovastatin; Morpholines; Oxidoreductases; Promoter Regions, Genetic; Recombinant Fusion Proteins; Restriction Mapping; RNA, Messenger; Saccharomyces cerevisiae; Transcription, Genetic

1996
Characterization of Saccharomyces cerevisiae CYP61, sterol delta22-desaturase, and inhibition by azole antifungal agents.
    The Journal of biological chemistry, 1997, Apr-11, Volume: 272, Issue:15

    Topics: Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ergosterol; Fluconazole; Ketoconazole; Oxidoreductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrophotometry, Atomic; Sterol 14-Demethylase

1997
Drug-induced phenotypes provide a tool for the functional analysis of yeast genes.
    Yeast (Chichester, England), 1998, Volume: 14, Issue:10

    Topics: Antifungal Agents; Benomyl; Cytochrome P-450 Enzyme System; Drug Resistance; Electron Transport Complex IV; Ergosterol; Gene Dosage; Genes, Fungal; Ketoconazole; Membrane Proteins; Miconazole; Molecular Biology; Mutagenesis; Open Reading Frames; Oxidoreductases; Phenotype; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sterol 14-Demethylase

1998
A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae.
    European journal of biochemistry, 2001, Volume: 268, Issue:4

    Topics: Androstenes; Antifungal Agents; beta-Galactosidase; Cytochrome c Group; Cytochromes c; Enzyme Inhibitors; Ergosterol; Ketoconazole; Models, Chemical; Naphthalenes; Oxygenases; Promoter Regions, Genetic; Recombinant Fusion Proteins; Response Elements; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Squalene Monooxygenase; Terbinafine; Transcriptional Activation

2001
Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs.
    Canadian journal of microbiology, 2003, Volume: 49, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Atropine; Bucladesine; Candida albicans; Chromatography, Gas; Cryptococcus neoformans; Cyclic AMP; Drug Synergism; Ergosterol; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Phosphodiesterase Inhibitors

2003
Lipid raft polarization contributes to hyphal growth in Candida albicans.
    Eukaryotic cell, 2004, Volume: 3, Issue:3

    Topics: Antifungal Agents; Bridged Bicyclo Compounds, Heterocyclic; Candida albicans; Cell Membrane; Cell Polarity; Ergosterol; Fatty Acids, Monounsaturated; Filipin; Hyphae; Ketoconazole; Membrane Microdomains; Sphingolipids; Sterols; Thiazoles; Thiazolidines

2004
Anti-proliferative synergy of lysophospholipid analogues and ketoconazole against Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae): cellular and ultrastructural analysis.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:5

    Topics: Animals; Chlorocebus aethiops; Drug Synergism; Drug Therapy, Combination; Ergosterol; Ketoconazole; Lysophospholipids; Microscopy, Electron; Microscopy, Electron, Scanning; Parasitic Sensitivity Tests; Phospholipid Ethers; Phosphorylcholine; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells

2005
Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors.
    International journal of antimicrobial agents, 2006, Volume: 27, Issue:6

    Topics: Animals; Cells, Cultured; Cytoskeleton; Ergosterol; Ketoconazole; Mice; Myocytes, Cardiac; Myofibrils; Triazoles; Trypanocidal Agents; Trypanosoma cruzi

2006
Antifolates as antimycotics? Connection between the folic acid cycle and the ergosterol biosynthesis pathway in Candida albicans.
    International journal of antimicrobial agents, 2006, Volume: 28, Issue:6

    Topics: Antifungal Agents; Candida albicans; Drug Synergism; Ergosterol; Folic Acid; Folic Acid Antagonists; Humans; Ketoconazole; Microbial Sensitivity Tests; Pyrimethamine

2006
Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Actins; Amebicides; Amoeba; Animals; Cell Line; Cell Survival; Cycloheximide; Cytochalasin D; Cytoskeleton; Dose-Response Relationship, Drug; Endothelial Cells; Ergosterol; Humans; Ketoconazole

2007
Effects of an ergosterol synthesis inhibitor on gene transcription of terpenoid biosynthesis in Blakeslea trispora.
    Current microbiology, 2008, Volume: 57, Issue:6

    Topics: Antifungal Agents; beta Carotene; Biosynthetic Pathways; Cytosol; Ergosterol; Fungal Proteins; Gene Expression Profiling; Ketoconazole; Mucorales; Terpenes; Transcription, Genetic; Ubiquinone

2008
Changes in the proteome of Candida albicans in response to azole, polyene, and echinocandin antifungal agents.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Adaptation, Physiological; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Caspofungin; Drug Resistance, Fungal; Echinocandins; Electrophoresis, Gel, Two-Dimensional; Ergosterol; Humans; Ketoconazole; Lipopeptides; Oxidative Stress; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Water-Electrolyte Balance

2010
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole

2010
Regulation of the hypoxic response in Candida albicans.
    Eukaryotic cell, 2010, Volume: 9, Issue:11

    Topics: Candida albicans; Cell Wall; Ergosterol; Fungal Proteins; Gene Expression Profiling; Gene Expression Regulation, Fungal; Genes, Fungal; Glycolysis; Ketoconazole; Multigene Family; Oligonucleotide Array Sequence Analysis; Oxygen; Transcription Factors

2010
Enhancement of β-carotene production by over-expression of HMG-CoA reductase coupled with addition of ergosterol biosynthesis inhibitors in recombinant Saccharomyces cerevisiae.
    Current microbiology, 2012, Volume: 64, Issue:2

    Topics: beta Carotene; Ergosterol; Gene Expression; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2012
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole

2016
5-hydroxymethyl-2-furaldehyde from marine bacterium Bacillus subtilis inhibits biofilm and virulence of Candida albicans.
    Microbiological research, 2018, Volume: 207

    Topics: Animals; Antifungal Agents; Bacillus subtilis; Biofilms; Caenorhabditis elegans; Candida albicans; Clotrimazole; Drug Synergism; Ergosterol; Furaldehyde; Hyphae; Ketoconazole; Miconazole; Virulence

2018
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019, Volume: 1864, Issue:3

    Topics: Biosynthetic Pathways; DNA, Mitochondrial; Endoplasmic Reticulum; Ergosterol; Gene Expression Regulation, Fungal; Ketoconazole; Lipid Droplets; Mitochondria; Oxidoreductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sterols

2019
Glutamine metabolism modulates azole susceptibility in
    eLife, 2020, 12-01, Volume: 9

    Topics: 14-alpha Demethylase Inhibitors; Animals; Azoles; Cell Line; Chagas Disease; Drug Interactions; Drug Resistance; Ergosterol; Glutamine; Humans; Ketoconazole; Trypanocidal Agents; Trypanosoma cruzi

2020