ketoconazole and ditiocarb

ketoconazole has been researched along with ditiocarb in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's7 (63.64)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Back, DJ; Eagling, VA; Tjia, JF1
Bhasker, CR; Birkett, DJ; Coulter, S; Miners, JO; Ong, CE1
McLean, S; Pass, GJ1
Araico, A; Cárcel-Trullols, J; Peris, JE; Saadeddin, A; Torres-Molina, F1
Amin, A; Hamza, AA1
Liu, XQ; Wang, GJ; Zhao, XP; Zhong, J1
Brock, B; Ly, VT1
Kubickova, B; Martinkova, M; Stiborova, M1

Other Studies

11 other study(ies) available for ketoconazole and ditiocarb

ArticleYear
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
    PLoS medicine, 2006, Volume: 3, Issue:11

    Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis

2006
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:2

    Topics: Animals; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Male; Microsomes, Liver; Phenacetin; Rats; Rats, Wistar; Substrate Specificity; Sulfaphenazole; Testosterone; Theophylline; Tolbutamide

1998
The xenobiotic inhibitor profile of cytochrome P4502C8.
    British journal of clinical pharmacology, 2000, Volume: 50, Issue:6

    Topics: Animals; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cells, Cultured; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Drug Interactions; Enzyme Inhibitors; Humans; Ketoconazole; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Spodoptera; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Transfection

2000
Inhibition of the microsomal metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula) by terpenes and other chemicals.
    Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:12

    Topics: Animals; Anti-Infective Agents, Local; Aryl Hydrocarbon Hydroxylases; Cyclohexanols; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Ditiocarb; Dose-Response Relationship, Drug; Eucalyptol; Humans; Hydroxylation; Ketoconazole; Kinetics; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Monoterpenes; Opossums; Oxidoreductases, N-Demethylating; Pesticide Synergists; Piperonyl Butoxide; Rats; Rats, Wistar; Terpenes

2002
Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all-trans-retinoic acid.
    Farmaco (Societa chimica italiana : 1989), 2004, Volume: 59, Issue:9

    Topics: Animals; Beverages; Citrus paradisi; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Enzyme Inhibitors; Ketoconazole; Rats; Tretinoin

2004
Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation.
    Toxicology, 2005, Mar-30, Volume: 208, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antiviral Agents; Calcium; Chemical and Drug Induced Liver Injury; Diclofenac; Ditiocarb; DNA Fragmentation; Glutathione; Ketoconazole; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Toxicity Tests

2005
CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Ditiocarb; Humans; Ketoconazole; Microsomes, Liver; Molecular Structure; Quinidine; Sulfaphenazole; Tranylcypromine; Vinblastine

2007
Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices.
    Chemico-biological interactions, 2011, Sep-05, Volume: 193, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Benzopyrans; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glucuronides; Glutathione; Hydroxylation; Ketoconazole; L-Lactate Dehydrogenase; Liver; Male; Mass Spectrometry; Molecular Structure; Necrosis; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Tranylcypromine; Triazoles

2011
Effects of cytochrome P450 inhibitors on peroxidase activity.
    Neuro endocrinology letters, 2012, Volume: 33 Suppl 3

    Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin

2012