ketoconazole has been researched along with diosbulbin b in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, H; Li, C; Lin, D; Peng, Y; Zheng, J | 1 |
| Gao, H; Li, W; Lin, D; Meng, D; Peng, Y; Smith, CV; Xu, Y; Zheng, J | 1 |
| Hu, ZH; Ji, LL; Jiang, JZ; Mao, YC; Wang, CH; Wang, ZT; Yang, BH; Yang, L | 1 |
| Guo, X; Huang, W; Lin, D; Peng, Y; Wang, K; Zheng, J | 1 |
4 other study(ies) available for ketoconazole and diosbulbin b
| Article | Year |
|---|---|
Cytochrome p450-mediated metabolic activation of diosbulbin B.
Topics: Acetylcysteine; Activation, Metabolic; Animals; Bile; Cytochrome P-450 CYP3A; Glutathione; Heterocyclic Compounds, 4 or More Rings; Humans; Ketoconazole; Lysine; Male; Microsomes, Liver; Rats; Urine | 2014 |
Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Furans; Glutathione; Heterocyclic Compounds, 4 or More Rings; Ketoconazole; Liver; Male; Mice; Structure-Activity Relationship | 2016 |
Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Hep G2 Cells; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Ketoconazole; Mice; Microsomes, Liver; NIH 3T3 Cells; Rats | 2017 |
Chemical Identity of Interaction of Protein with Reactive Metabolite of Diosbulbin B In Vitro and In Vivo.
Topics: Activation, Metabolic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Glutathione; Heterocyclic Compounds, 4 or More Rings; Ketoconazole; Liver; Lysine; Male; Mice; Microsomes, Liver; Proteins | 2017 |