ketoconazole and desoxycorticosterone

ketoconazole has been researched along with desoxycorticosterone in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199010 (52.63)18.7374
1990's2 (10.53)18.2507
2000's1 (5.26)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Berger, ML; Hahner, S; Hammerschmidt, F; Peric-Simov, B; Schirbel, A; Zolle, IM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Rahal, S; Roberts, R; Senciall, IR1
Aron, DC; Bravo, EL; Saadi, HF1
Bertagna, X; Billaud, L; Cerdas, S; Guilhaume, B; Laudat, MH; Luton, JP1
Britton, H; Chow, D; Lightner, E; New, M; Shehab, Z1
Amery, W; Beerens, D; Caers, I; Coene, MC; De Coster, R; Haelterman, C1
Dörr, G; Engelhardt, D; Jaspers, C; Knorr, D1
Goshima, E; Hirai, M; Miura, K; Murase, H; Murayama, M; Noritake, N; Takeda, N; Yamakita, N; Yasuda, K1
Higashi, Y; Inano, H; Omura, M; Oshima, H; Suzuki, K1
Rahal, SR; Roberts, R; Senciall, IR1
Nonaka, Y; Ohnishi, T; Okamoto, M; Wada, A1
Ikeda, M; Katagiri, M; Koshida, H; Miyamori, I; Nagai, K; Suhara, K; Takeda, R1
Itagaki, E; Katagiri, M; Miyamori, I; Nagai, K; Takeda, R1
Arlt, W; de Herder, WW; de Jong, FH; Feelders, RA; Hofland, J; Hofland, LJ; Steenbergen, J; Taylor, AE; van der Pas, R; van Koetsveld, PM1
Aceves-Ramos, A; Gaona, B; Romano, MC; Valdez, RA; Willms, K1
Fujii, Y; Kouchi, M; Matsumoto, I; Miyawaki, I; Tochitani, T; Yamada, T; Yamashita, A1
Fujii, Y; Kouchi, M; Matsumoto, I; Miyawaki, I; Tochitani, T; Yamashita, A1

Reviews

1 review(s) available for ketoconazole and desoxycorticosterone

ArticleYear
[Short term effects of ketoconazole in Cushing's syndrome].
    Annales d'endocrinologie, 1989, Volume: 50, Issue:6

    Topics: Adult; Androgens; Cushing Syndrome; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glucocorticoids; Humans; Ketoconazole; Male; Middle Aged

1989

Other Studies

18 other study(ies) available for ketoconazole and desoxycorticosterone

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Adrenal Cortex; Animals; Binding Sites; Etomidate; Humans; Hydroxylation; Iodine Radioisotopes; Kinetics; Male; Molecular Structure; Rats; Rats, Wistar; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Corticosteroid side chain oxidations--II. Metabolism of 20-dihydro steroids and evidence for steroid acid formation by direct oxidation at C-21.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Corticosterone; Desoxycorticosterone; Ketoconazole; Oxidation-Reduction; Progesterone; Rabbits; Steroids

1992
Feminizing adrenocortical tumor: steroid hormone response to ketoconazole.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:2

    Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Aldosterone; Androgen-Insensitivity Syndrome; Corticosterone; Desoxycorticosterone; Estradiol; Estrogens; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Testosterone

1990
Adrenal response in children receiving high doses of ketoconazole for systemic coccidioidomycosis.
    The Journal of pediatrics, 1988, Volume: 112, Issue:3

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Child; Coccidioidomycosis; Desoxycorticosterone; Humans; Hydrocortisone; Ketoconazole; Steroid 11-beta-Hydroxylase; Time Factors

1988
Effects of high dose ketoconazole therapy on the main plasma testicular and adrenal steroids in previously untreated prostatic cancer patients.
    Clinical endocrinology, 1986, Volume: 24, Issue:6

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Aged; Androgens; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Testosterone

1986
Ketoconazole blocks cortisol secretion in man by inhibition of adrenal 11 beta-hydroxylase.
    Klinische Wochenschrift, 1985, Jul-01, Volume: 63, Issue:13

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenocorticotropic Hormone; Corticosterone; Cortodoxone; Cushing Syndrome; Desoxycorticosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases

1985
Response of plasma adrenal steroids to synthetic ACTH under ketoconazole in man.
    Endocrinologia japonica, 1987, Volume: 34, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldehyde-Lyases; Aldosterone; Corticosterone; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase

1987
Ketoconazole as a possible universal inhibitor of cytochrome P-450 dependent enzymes: its mode of inhibition.
    Endocrinologia japonica, 1987, Volume: 34, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Humans; Ketoconazole; Male; Microsomes; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Inbred Strains; Spectrophotometry; Steroid 17-alpha-Hydroxylase; Testis

1987
Ketoconazole inhibition of progesterone oxidation by the rabbit.
    Biochemical pharmacology, 1988, Oct-01, Volume: 37, Issue:19

    Topics: Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Oxidation-Reduction; Progesterone; Rabbits; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1988
Inhibition of bovine adrenocortical mitochondrial cytochrome P-450(11)beta-mediated reactions by imidazole derivatives and mineralocorticoid analogs.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:5

    Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Clotrimazole; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Etomidate; Imidazoles; Ketoconazole; Miconazole; Mineralocorticoids; Mitochondria

1988
Effect of ketoconazole (an imidazole antimycotic agent) and other inhibitors of steroidogenesis on cytochrome P450-catalyzed reactions.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:1

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Aminoglutethimide; Animals; Cattle; Cholesterol; Corticosterone; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Electron Transport; In Vitro Techniques; Ketoconazole; Mitochondria; Pregnenolone; Steroids

1986
[The effect of ketoconazole and some other inhibitors of steroidogenesis on P-450 11 beta-catalyzed reactions].
    Nihon Naibunpi Gakkai zasshi, 1985, Feb-20, Volume: 61, Issue:2

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Antineoplastic Agents; Catalysis; Corticosterone; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Dihydrotestosterone; In Vitro Techniques; Ketoconazole; Mitochondria

1985
Fluconazole inhibits human adrenocortical steroidogenesis in vitro.
    The Journal of endocrinology, 2012, Volume: 215, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cortodoxone; Desoxycorticosterone; Fluconazole; Humans; Hydrocortisone; Ketoconazole; Pregnenolone; Progesterone

2012
Steroid synthesis by Taenia crassiceps WFU cysticerci is regulated by enzyme inhibitors.
    General and comparative endocrinology, 2013, Jul-01, Volume: 188

    Topics: Androstenedione; Animals; Chromatography, Thin Layer; Danazol; Desoxycorticosterone; Enzyme Inhibitors; Estradiol; Ketoconazole; Steroids; Taenia

2013
Physiological and drug-induced changes in blood levels of adrenal steroids and their precursors in cynomolgus monkeys: An application of steroid profiling by LC-MS/MS for evaluation of the adrenal toxicity.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:9

    Topics: Adrenal Glands; Aldosterone; Androgens; Animals; Chromatography, Liquid; Circadian Rhythm; Desoxycorticosterone; Female; Humans; Hydrocortisone; Ketoconazole; Macaca fascicularis; Male; Metyrapone; Steroid 11-beta-Hydroxylase; Tandem Mass Spectrometry

2019
Dose- and time-dependent changes in blood and adrenal levels of multiple steroids in rats after administration of ketoconazole with or without ACTH.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:9

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chromatography, Liquid; Desoxycorticosterone; Dose-Response Relationship, Drug; Ketoconazole; Male; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Time Factors

2019