ketoconazole has been researched along with desloratadine in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cayen, MN; Chen, KJ; Clement, RP; Huie, K; Snow, M; Yumibe, N | 1 |
| Affrime, M; Banfield, C; Herron, J; Keung, A; Padhi, D | 1 |
| Alton, KB; Alvarez, N; Chowdhury, SK; Ghosal, A; Gupta, S; Lu, X; Ramanathan, R; Su, AD; Yuan, Y; Zbaida, S | 1 |
| Kulig, M; Lisowski, B; Polak, S; Wiśniowska, B | 1 |
1 review(s) available for ketoconazole and desloratadine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for ketoconazole and desloratadine
| Article | Year |
|---|---|
Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole.
Topics: Adult; Analysis of Variance; Antifungal Agents; Area Under Curve; Cross-Over Studies; Drug Interactions; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Ketoconazole; Loratadine; Male; Middle Aged | 2002 |
5 other study(ies) available for ketoconazole and desloratadine
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Binding Sites; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Histamine H1 Antagonists; Humans; In Vitro Techniques; Ketoconazole; Loratadine; Microsomes, Liver; Mixed Function Oxygenases; Models, Molecular; Oxidation-Reduction; Piperidines; Pyridines; Quinidine; Recombinant Proteins; Substrate Specificity; Troleandomycin | 1996 |
Metabolism of loratadine and further characterization of its in vitro metabolites.
Topics: Administration, Oral; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Liver; Loratadine; Microsomes, Liver; Recombinant Proteins; Tablets; Tandem Mass Spectrometry | 2009 |
Drug interaction at hERG channel: In vitro assessment of the electrophysiological consequences of drug combinations and comparison against theoretical models.
Topics: Arrhythmias, Cardiac; Drug Combinations; Drug Interactions; Electrophysiology; ERG1 Potassium Channel; HEK293 Cells; Humans; In Vitro Techniques; Ketoconazole; Loratadine; Models, Theoretical; Patch-Clamp Techniques | 2018 |