ketoconazole has been researched along with dehydroepiandrosterone in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (33.33) | 18.7374 |
| 1990's | 11 (36.67) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Akalin, S | 1 |
| Chouinard, G; Dhar, V; Ghadirian, AM; Keller, R; Murphy, BE | 1 |
| Biason, A; Boscaro, M; Mantero, F; Scaroni, C; Sonino, N | 1 |
| Cedeno, J; Glueck, CJ; Mendoza, SG; Nucete, H; Speirs, J; Velazquez, E | 1 |
| Conget, JI; Ferrer, J; González-Clemente, JM; Halperin, I; Martinez-Osaba, MJ; Vilardell, E | 1 |
| Al-Sarraf, M; Decker, DA; Kresge, C; Subramanian, MG; Tapazoglou, E | 1 |
| Amery, W; Beerens, D; Caers, I; Coene, MC; De Coster, R; Haelterman, C | 1 |
| Heikkinen, J; Kauppila, A; Martikainen, H; Ruokonen, A | 1 |
| Trachtenberg, J; Zadra, J | 1 |
| Aste, N; Lecca, U; Marcello, C; Medda, F; Parodo, G; Pascalis, P; Pia, G; Puligheddu, P | 1 |
| Cantwell, BM; Dowsett, M; Harris, AL | 1 |
| Berselli, ME; Loli, P; Tagliaferri, M | 1 |
| Goshima, E; Hirai, M; Miura, K; Murase, H; Murayama, M; Noritake, N; Takeda, N; Yamakita, N; Yasuda, K | 1 |
| Bochra, C; Feldman, D; Loose, DS; Pont, A; Reitz, RE; Stevens, DA; Williams, PL | 1 |
| Trachtenberg, J | 1 |
| Khalil, MW; Killinger, DW; Strutt, B; Vachon, D | 1 |
| Brodie, AM; Li, JS; Li, Y; Son, C | 1 |
| Gökmen, O; Gülekli, B; Işik, AZ; Senöz, S | 1 |
| Frederick, S; Reus, VI; Wolkowitz, OM | 1 |
| Akaza, H; Fujikura, T; Ideyama, Y; Ishikawa, H; Kudoh, M; Nakahara, T; Nanya, T; Shikama, H; Susaki, Y; Tanimoto, K | 1 |
| Bech, P; Breum, L; Hammer, M; Jarløv, N; Raabaek Olsen, L; Schütze, T | 1 |
| Iranmanesh, A; Mulligan, T; Veldhuis, JD; Zwart, A | 1 |
| Kibaly, C; Mensah-Nyagan, AG; Meyer, L; Patte-Mensah, C | 1 |
| Białońska, A; Kołek, T; Milecka, N; Panek, A; Świzdor, A | 1 |
| Asahi, S; Hara, T; Hitaka, T; Kaku, T; Kusaka, M; Miki, H; Takahashi, J; Takeuchi, T; Tasaka, A; Yamaoka, M | 1 |
| Amory, JK; Anawalt, BD; Bremner, WJ; Lin, K; Marck, BT; Matsumoto, AM; Nya-Ngatchou, JJ; Page, ST; Roth, MY | 1 |
| Guo, L; Li, L; Wu, Z; Xu, Z; Zhen, X; Zheng, LT | 1 |
| Bendall, S; Garner, B; Hetrick, SE; Phillips, LJ | 1 |
| Murakami, M; Niwa, T; Suzuki, A; Tani, M | 1 |
2 review(s) available for ketoconazole and dehydroepiandrosterone
| Article | Year |
|---|---|
Antiglucocorticoid treatments in psychiatry.
Topics: Dehydroepiandrosterone; Hormone Antagonists; Humans; Ketoconazole; Mental Disorders | 1997 |
Antiglucocorticoid and related treatments for psychosis.
Topics: Dehydroepiandrosterone; Dexamethasone; Glucocorticoids; Humans; Hypothalamo-Hypophyseal System; Ketoconazole; Mifepristone; Pituitary-Adrenal System; Psychotic Disorders; Randomized Controlled Trials as Topic | 2016 |
5 trial(s) available for ketoconazole and dehydroepiandrosterone
| Article | Year |
|---|---|
Effects of ketoconazole in hirsute women.
Topics: Adult; Dehydroepiandrosterone; Double-Blind Method; Estradiol; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Progesterone; Severity of Illness Index; Testosterone | 1991 |
Response to steroid suppression in major depression resistant to antidepressant therapy.
Topics: Adult; Aminoglutethimide; Antidepressive Agents; Dehydroepiandrosterone; Depressive Disorder; Dexamethasone; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Hydrocortisone; Ketoconazole; Male; Metyrapone; Middle Aged; Psychiatric Status Rating Scales | 1991 |
Effect of ketoconazole on plasma sex hormones, lipids, lipoproteins, and apolipoproteins in hyperandrogenic women.
Topics: Adolescent; Adult; Androgens; Apolipoproteins; Cholesterol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estradiol; Female; Gonadal Steroid Hormones; Humans; Ketoconazole; Lipids; Lipoproteins; Polycystic Ovary Syndrome; Reference Values | 1990 |
Comparison of four different treatment regimes in hirsutism related to polycystic ovary syndrome.
Topics: Adolescent; Adult; Androgen Antagonists; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Contraceptives, Oral, Combined; Cyproterone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Ketoconazole; Luteinizing Hormone; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Spironolactone; Testosterone | 1996 |
Androgen synthesis in the gonadotropin-suppressed human testes can be markedly suppressed by ketoconazole.
Topics: 14-alpha Demethylase Inhibitors; 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androgens; Androstenedione; Contraception; Dehydroepiandrosterone; Drug Design; Drug Synergism; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Middle Aged; Oligopeptides; Placebos; Spermatogenesis; Testis; Testosterone; Young Adult | 2013 |
23 other study(ies) available for ketoconazole and dehydroepiandrosterone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Low-dose ketoconazole treatment in hirsute women.
Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Drug Evaluation; Estradiol; Female; Follicle Stimulating Hormone; Hair; Hirsutism; Humans; Ketoconazole; Luteinizing Hormone; Prolactin; Testosterone | 1990 |
Evaluation of clinical and hormonal effects in hirsute women treated with ketoconazole.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydroxyprogesterones; Ketoconazole; Testosterone | 1990 |
High-dose ketoconazole therapy in patients with metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Androstenedione; Combined Modality Therapy; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Ketoconazole; Luteinizing Hormone; Male; Middle Aged; Neoplasm Metastasis; Orchiectomy; Prostatic Neoplasms; Testosterone | 1986 |
Effects of high dose ketoconazole therapy on the main plasma testicular and adrenal steroids in previously untreated prostatic cancer patients.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Aged; Androgens; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Testosterone | 1986 |
Hormonal and clinical effects of ketoconazole in hirsute women.
Topics: Adult; Androgens; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Hydrocortisone; Ketoconazole; Luteinizing Hormone; Ovary; Pituitary-Adrenal System; Testosterone | 1988 |
Steroid synthesis inhibition by ketoconazole: sites of action.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aldehyde-Lyases; Androgens; Androstenedione; Chorionic Gonadotropin; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 1988 |
Short term treatment with ketoconazole: effects on gonadal and adrenal steroidogenesis in women.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Radioimmunoassay; Testosterone | 1987 |
High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Menopause; Middle Aged; Sex Hormone-Binding Globulin; Testosterone | 1988 |
Use of ketoconazole in the treatment of Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Time Factors | 1986 |
Response of plasma adrenal steroids to synthetic ACTH under ketoconazole in man.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldehyde-Lyases; Aldosterone; Corticosterone; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase | 1987 |
Ketoconazole blocks adrenal steroid synthesis.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androstenedione; Animals; Antifungal Agents; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Male; Piperazines; Rats | 1982 |
Ketoconazole therapy in advanced prostatic cancer.
Topics: Acid Phosphatase; Aged; Androstenedione; Dehydroepiandrosterone; Follow-Up Studies; Humans; Ketoconazole; Male; Prostatic Neoplasms; Testosterone; Time Factors | 1984 |
Effect of dexamethasone and cytochrome P450 inhibitors on the formation of 7 alpha-hydroxydehydroepiandrosterone by human adipose stromal cells.
Topics: Adipose Tissue; Aminoglutethimide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dexamethasone; Humans; Ketoconazole; Metyrapone; Mifepristone; Stromal Cells | 1994 |
Synthesis and evaluation of pregnane derivatives as inhibitors of human testicular 17 alpha-hydroxylase/C17,20-lyase.
Topics: Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Humans; Ketoconazole; Male; Microsomes; Pregnanes; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Testis | 1996 |
YM116, 2-(1H-imidazol-4-ylmethyl)-9H-carbazole, decreases adrenal androgen synthesis by inhibiting C17-20 lyase activity in NCI-H295 human adrenocortical carcinoma cells.
Topics: Adrenal Cortex Hormones; Adrenocortical Carcinoma; Androgens; Androstenedione; Carbazoles; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Male; Microsomes; Steroid 17-alpha-Hydroxylase; Testis; Tumor Cells, Cultured | 1999 |
A case of sequential anti-stress medication in a patient with major depression resistant to amine-reuptake inhibitors.
Topics: Amines; Antidepressive Agents; Anxiety Disorders; Dehydroepiandrosterone; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; GABA Modulators; Humans; Hydrocortisone; Ketoconazole; Lithium Carbonate; Mianserin; Middle Aged; Oxazepam; Prognosis; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Severity of Illness Index; Stress, Psychological | 1999 |
Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.
Topics: Adolescent; Adult; Aged; Aging; Androgens; Androstenedione; Dehydroepiandrosterone; Feedback; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Ketoconazole; Luteinizing Hormone; Male; Middle Aged; Prolactin; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Testosterone; Thyrotropin; Time Factors | 2001 |
Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord.
Topics: Animals; Base Sequence; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; DNA Primers; Enzyme Inhibitors; Gene Expression; Injections, Spinal; Ketoconazole; Male; Pain; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2008 |
Hydroxylation of DHEA, androstenediol and epiandrosterone by Mortierella isabellina AM212. Evidence indicating that both constitutive and inducible hydroxylases catalyze 7α- as well as 7β-hydroxylations of 5-ene substrates.
Topics: Androstenediol; Androsterone; Binding Sites; Catalysis; Crystallography, X-Ray; Cycloheximide; Dehydroepiandrosterone; Hydroxylation; Ketoconazole; Mixed Function Oxygenases; Molecular Structure; Mortierella | 2011 |
Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys.
Topics: Adrenal Glands; Androgen Antagonists; Androgens; Animals; Cell Line, Tumor; Cells, Cultured; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Macaca fascicularis; Male; Naphthalenes; Orchiectomy; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone | 2012 |
Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Allosteric Regulation; Animals; Anti-Inflammatory Agents; Cell Line; Culture Media, Conditioned; Dehydroepiandrosterone; Enzyme Induction; Ethylenediamines; Interleukin-10; Ketoconazole; Lipopolysaccharides; Male; Mice; Microglia; Narcotic Antagonists; Neuroblastoma; Neuroimmunomodulation; Nitric Oxide; Nitric Oxide Synthase Type II; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, sigma; Sigma-1 Receptor; Tumor Necrosis Factor-alpha | 2015 |
Stimulatory and Inhibitory Effects of Steroid Hormones and Human Cytochrome P450 (CYP) 3A Inhibitors on Cortisol 6β-Hydroxylation Catalyzed by CYP3A Subfamilies.
Topics: Antifungal Agents; Catalysis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxylation; Itraconazole; Ketoconazole; Steroids; Testosterone | 2023 |