ketoconazole and debrisoquin

ketoconazole has been researched along with debrisoquin in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (20.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (40.00)	29.6817
2010's	2 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Atiba, JO; Blaschke, TF; Wilkinson, GR	1
AL-Shurbaji, A; Annas, A; Dahl, ML; Lindh, JD; Meurling, L	1

Trials

2 trial(s) available for ketoconazole and debrisoquin

Article	Year
Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine. British journal of clinical pharmacology, 1989, Volume: 28, Issue:2 Topics: Adult; Debrisoquin; Humans; Hydantoins; Hydroxylation; Isoquinolines; Ketoconazole; Male; Mephenytoin; Oxidation-Reduction; Phenotype; Stereoisomerism	1989
Effect of ketoconazole on venlafaxine plasma concentrations in extensive and poor metabolisers of debrisoquine. European journal of clinical pharmacology, 2003, Volume: 59, Issue:5-6 Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Area Under Curve; Cyclohexanols; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Debrisoquin; Drug Interactions; Female; Genotype; Half-Life; Humans; Ketoconazole; Male; Middle Aged; Phenotype; Venlafaxine Hydrochloride; White People	2003

Article

Year

Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine.

British journal of clinical pharmacology, 1989, Volume: 28, Issue:2

Topics: Adult; Debrisoquin; Humans; Hydantoins; Hydroxylation; Isoquinolines; Ketoconazole; Male; Mephenytoin; Oxidation-Reduction; Phenotype; Stereoisomerism

1989

Effect of ketoconazole on venlafaxine plasma concentrations in extensive and poor metabolisers of debrisoquine.

European journal of clinical pharmacology, 2003, Volume: 59, Issue:5-6

Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Area Under Curve; Cyclohexanols; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Debrisoquin; Drug Interactions; Female; Genotype; Half-Life; Humans; Ketoconazole; Male; Middle Aged; Phenotype; Venlafaxine Hydrochloride; White People

2003

Other Studies

3 other study(ies) available for ketoconazole and debrisoquin

Article	Year
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012