ketoconazole has been researched along with clotrimazole in 214 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (29.44) | 18.7374 |
| 1990's | 41 (19.16) | 18.2507 |
| 2000's | 53 (24.77) | 29.6817 |
| 2010's | 49 (22.90) | 24.3611 |
| 2020's | 8 (3.74) | 2.80 |
| Authors | Studies |
|---|---|
| Driscoll, MD; Lafite, P; Levy, C; Leys, D; Mast, N; McLean, KJ; Munro, AW; Pikuleva, IA; Rigby, SE | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Emami, S; Keighobadi, M; Tavangar, P | 1 |
| Bizzarri, B; Carradori, S; D'Ascenzio, M; De Monte, C; Grande, R; Mari, E; Patsilinakos, A; Ragno, R; Rivanera, D; Sabatino, M; Secci, D; Zicari, A | 1 |
| Cantürk, Z; Çavuşoğlu, BK; Yurttaş, L | 1 |
| Wang, SQ; Wang, YF; Xu, Z | 1 |
| Sun, B; Sun, N; Sun, Y; Tian, L; Zhao, D; Zhao, L; Zhao, S | 1 |
| Gao, F; Huang, G; Xiao, J | 1 |
| Prasher, P; Sharma, M | 1 |
| James, MO; Sloan, KB | 1 |
| Dyer, RL; Ellames, GJ; Hamill, BJ; Manley, PW; Pope, AM | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K | 1 |
| Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Bergès, T; Bouchara, JP; Chabasse, D; Hennequin, C; Tronchin, G; Vandeputte, P | 1 |
| Aghatabay, NM; Dülger, B; Haciu, D; Karabiyik, T; Neshat, A; Somer, M | 1 |
| Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
| Guengerich, FP; Isin, EM | 1 |
| Aghatabay, NM; Dulger, B; Gucin, F; Senel, M; Somer, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Deising, HB; Serfling, A; Wohlrab, J | 1 |
| Aghatabay, NM; Cevik, H; Dulger, B; Mahmiani, Y | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Kelly, DE; Kelly, SL; Manning, NJ; Merkamm, M; Parker, JE; Pompon, D | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC; Marczylo, TH; Parker, JE; Warrilow, AG | 1 |
| Pratim Roy, P; Roy, K | 1 |
| Bergès, T; Bouchara, JP; Chabasse, D; Renier, G; Rocher, F; Tronchin, G; Vandeputte, P | 1 |
| Aghatabay, NM; Baş, A; Dülger, B; Gücin, F; Kircali, A; Sen, G; Yazicioğlu, MB | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Asim Kaplancikli, Z; Demirci, F; Işcan, G; Khan, S; Ozdemir, A; Turan-Zitouni, G | 1 |
| Muftuoglu, Y; Mustata, G | 1 |
| Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Warrilow, AG; Weig, M | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Sen, S; Sinha, N | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Avery, VM; Sykes, ML | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Akdemir, A; Bizzarri, B; Bolasco, A; Caprara, F; Carradori, S; De Monte, C; Mari, E; Mollica, A; Rivanera, D; Secci, D; Zicari, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Aktumsek, A; Bizzarri, B; Carradori, S; Chimenti, P; De Monte, C; Mari, E; Mollica, A; Rivanera, D; Secci, D; Zengin, G; Zicari, A | 1 |
| Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW | 1 |
| Benhamou, RI; Dorot, O; Elias, R; Fridman, M; Jaber, QZ; Oved, K; Pichinuk, E; Zada, SL | 1 |
| Granger, SE; Loo, P; Tobin, JM | 1 |
| Fong, IW | 1 |
| Coudray, AM; Fagot, D; Forgue-Lafitte, ME; Mester, J | 1 |
| Georgiev, VS | 1 |
| Fotos, PG; Hellstein, JW; Vincent, SD | 1 |
| Aoki, K; Hosaka, J; Uchida, K; Yamaguchi, H | 1 |
| Falk, ES; Gasior-Chrzan, B; Stenvold, SE | 1 |
| Lovas, J; Varga, A | 1 |
| Lenhart, K; Merkunová, A | 1 |
| Visvanathan, R | 1 |
| Chafey, S; Franker, C; Hardy, WD; Lucatorto, FM | 1 |
| Bard, M; Broughton, MC; Lees, ND; Sanglard, D | 1 |
| Kitazawa, K; Nakade, T; Uchida, Y | 1 |
| Kozený, M; Latinák, J; Lenhart, K; Merkunová, A; Walterová, D | 1 |
| Ciancio, SG | 1 |
| Ioannides, C; Lewis, DF; Parke, DV; Rodrigues, AD | 1 |
| Dwernicka, B; Macura, AB | 1 |
| Guzelian, PS; Hostetler, KA; Levin, W; Molowa, DT; Thomas, PE; Wrighton, SA | 1 |
| Abarca, L; Bragulat, M; Bruguera, T; Cabañes, FJ | 1 |
| Odds, FC; Webster, CE | 1 |
| Brodell, RT; Kyanko, ME; Pontasch, MJ | 1 |
| Abbott, AB; Cockayne, A; Hayward, J; Odds, FC | 1 |
| Cauwenbergh, G | 1 |
| Bastide, JM; Bastide, M; Jouvert, S; Lebecq, JC; Mallie, M; Montes, B | 1 |
| Danpakdi, K; Kulpreedarat, T; Thamlikitkul, V; Visuthisakchai, S | 1 |
| Capdevila, J; Falck, JR; Gil, L; Marnett, LJ; Mason, JI; Orellana, M; Yadagiri, P | 1 |
| Cavanna, C; Garavelli, PL; Maccabruni, A; Michelone, G | 1 |
| Clayton, YM; Hay, RJ; Howell, SA; Noble, WC | 1 |
| Kalter, DC; McBride, ME; Wolf, JE | 1 |
| Nonaka, Y; Ohnishi, T; Okamoto, M; Wada, A | 1 |
| Iscan, M; Kairaluoma, M; Pasanen, M; Pelkonen, O; Sotaniemi, EA; Taskinen, T | 1 |
| Davis, CP; Gudewicz, TM; Mader, JT | 1 |
| Ah-Sing, E; Ioannides, C; Morris, BA; Rodrigues, AD; Waddell, PR; Wolf, CR | 1 |
| Meingassner, JG; Mieth, H; Petranyi, G | 2 |
| Verö, T | 1 |
| Adám, J; Ba, J | 1 |
| Holmberg, K | 1 |
| Gibson, GG; Ioannides, C; Parke, DV; Rodrigues, AD | 1 |
| Dix, BA; Freudenberger, J; Funke, PT; Georgopapadakou, NH; Smith, SA | 1 |
| Franklin, MR; Ritter, JK | 1 |
| Napoli, JL; Williams, JB | 1 |
| Bickers, DR; Das, M; Kaufmann, I; Merk, HF; Mukhtar, H | 1 |
| De Bernardis, F; Lorenzini, R; Mercantini, R | 1 |
| Davies, RR; Zaini, F | 1 |
| Estabrook, RW; Mason, JI; Sheets, JJ; Wise, CA | 1 |
| Goldberg, PE; Kozinn, PJ; Wise, GJ | 1 |
| Monif, GR | 1 |
| Schuster, I | 1 |
| del Palacio-Hernanz, AD; Lopez-Gomez, S; Moore, MK | 1 |
| Rukavishnikova, VM; Sheklakov, ND | 1 |
| Ferrante, A; Rowan-Kelly, B; Thong, YH | 1 |
| Kostiala, AA; Kostiala, I | 1 |
| Klimek, JJ; Nightingale, CH; Owens, NJ; Quercia, RA; Quintiliani, R | 1 |
| Abbott, AB; Odds, FC; Webster, CE | 1 |
| Janin-Mercier, A; Saurat, JH | 1 |
| Feldman, D; Loose, DS; Stover, EP | 1 |
| Arai, T | 1 |
| Berman, JD | 1 |
| Awouters, F; Janssen, PA; Levron, JC; Niemegeers, CJ | 1 |
| Feingold, DS; Sud, IJ | 1 |
| Bastide, JM; Bastide, M; Jouvert, S | 1 |
| Drutz, DJ | 1 |
| Qadripur, SA | 1 |
| Artis, WM; Granade, TC; Mothershead, MA | 1 |
| Ditrich, O; Otcenásek, M | 1 |
| Arai, T; Shigematsu, ML; Uno, J | 1 |
| Fuller, BL; Tolman, EL | 1 |
| Collins, JR; Van Sickels, JE | 1 |
| Frost, BM; Valiant, ME | 1 |
| Gorman, SP; Scott, EM; Wright, LR | 1 |
| El-On, J; Jacobs, GP; Livshin, R; Weinrauch, L | 1 |
| Grassick, K; Humphries, M; Miller, PI | 1 |
| Bingham, JS | 1 |
| Bujdáková, H; Klobusický, M; Múcková, M; Sidóová, E | 1 |
| Bernhardt, R; Denner, K; Doehmer, J; Schmalix, W; Vogel, R | 1 |
| Datto, GA; Samatovicz, RA; Wolff, DJ | 1 |
| Pai, ST; Platt, MW | 1 |
| Greenspan, D | 1 |
| Christensen, S; Meriwether, C; Mummaw, N; Schmitt, C; Sobel, JD; Stein, G | 1 |
| Adams, JS; Arbelle, JE; Clemens, TL; Gray, RW; Horiuchi, N; Ren, SY; Shany, S | 1 |
| al-Fouzan, AS; Kubec, K; Nanda, A | 1 |
| Stehlich, G; Török, I | 1 |
| Agarwal, N; Austria, L; Cerabona, T; Policastro, A; Savino, JA; Wry, P | 1 |
| Mummaw, N; Stein, GE | 1 |
| Bannatyne, RM; Fong, IW; Wong, P | 1 |
| Hegemann, L; Lahijani, KI; Toso, SM; Uitto, J; Webster, GF | 1 |
| Chodkowski, J; Fijałek, Z; Warowna, M | 1 |
| Forn, J; García-Rafanell, J; Merlos, M; Vericat, ML | 1 |
| Barbuch, R; Bard, M; Gachotte, D; Koegel, C; Lees, ND; Pierson, CA | 1 |
| Drews, G; Welker, S | 1 |
| Benkó, I; Hernádi, F; Kovács, P; Megyeri, A | 1 |
| Feldman, SR; Fleischer, AB; Smith, ES | 1 |
| Ahring, PK; Christophersen, P; Hansen, C; Jensen, BS; Jorgensen, TD; Olesen, SP; Silahtaroglu, A; Strobaek, D | 1 |
| Arikian, SR; Doyle, JJ; Einarson, TR; Shear, NH | 1 |
| Espasa, M; Jimenez, T; Lagunas, C; López-Jodra, O; Mendez, R; Morera, Y; Torres-Rodríguez, JM | 1 |
| Benko, I; Hernádi, F; Kiss, A; Kovács, P; Kraicsovits, F; Megyeri, A; Somogyi, G; Tegyey, Z | 1 |
| Bouchara, JP; Chabasse, D; Declerk, P; Defontaine, A; Hallet, JN; Planchenault, C | 1 |
| Christophersen, P; Jensen, BS; Jorgensen, NK; Odum, N; Olesen, SP | 1 |
| Allen, JW; Hansen, TW; Tommarello, S | 1 |
| Calvo, T; Cuétara, S; del Palacio, A; Garau, M; Pérez, A; Sánchez-Alor, G | 1 |
| Andersson, DA; Andersson, TL; Högestätt, ED; Movahed, P; Zygmunt, PM | 1 |
| Fowler, SM; Friedberg, T; Pritchard, MP; Riley, RJ; Sutcliffe, MJ; Wolf, CR | 1 |
| Ringdahl, EN | 1 |
| Ellepola, AN; Samaranayake, LP | 2 |
| Cole, WC; Iftinca, M; Triggle, CR; Waldron, GJ | 1 |
| Bonito, AJ; Patton, LL; Shugars, DA | 1 |
| Crego, AL; Gómez, J; Lavandera, JL; Marina, ML | 1 |
| Atencio, R; Cisneros-Fajardo, EJ; Lehmann, T; Lira, R; Navarro, M; Sánchez-Delgado, RA; Silva, P; Urbina, JA | 1 |
| Bozhkova, K; Vasileva, P | 1 |
| Clarkson, JE; Eden, OB; Worthington, HV | 3 |
| Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Serada, S; Tajima, K; Takano, R | 1 |
| Fernández-Torres, B; Guarro, J; Pereiro, M | 1 |
| Fladung, B; Merk, HF; Suschka, S | 1 |
| Farhadi, K; Maleki, R | 1 |
| Abdel-Moety, EM; AbouAl-Alamein, AM; Kelani, KM; Khattab, FI | 1 |
| Engelen, M; Rochette, F; Vanden Bossche, H | 1 |
| Bork, S; Claveria, FG; Fujisaki, K; Igarashi, I; Matsuo, T; Yokoyama, N | 2 |
| Fernández-Torres, B; Guarro, J; Inza, I | 1 |
| Abramovich, RA; Gorbunova, NA; Papazova, NA | 1 |
| Anzellotti, A; Rieber, M; Sánchez-Delgado, RA; Strasberg Rieber, M | 1 |
| Carrillo-Muñoz, AJ; Casals, J; del Valle, O; Guardià, C; Guglietta, A; Palacín, C; Quindós, G; Rodríguez, V | 1 |
| Ching, Y; Colmenares, I; Correia, H; Fraile, G; Hernández, A; Millán, Y; Navarro, M; Ojeda, LE; Velásquez, M | 1 |
| Chong, PP; D' Silva, EC; Looi, CY; Ng, KP; Rosli, R; Seow, HF | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
| Müller, RH; Souto, EB | 1 |
| Gregoriou, S; Ifantides, A; Katsambas, A; Kontochristopoulos, G; Rigopoulos, D | 1 |
| Barker, S; Essmann, M; Larsen, B; Schmidt, M | 1 |
| Fick, J; Lindberg, RH; Tysklind, M | 1 |
| Jornet-García, V; López-Jornet, P; Martínez-Beneyto, Y; Velandrino-Nicolás, A | 1 |
| Gianni, S; Montemiglio, LC; Savino, C; Vallone, B | 1 |
| Adlnasab, L; Ebrahimzadeh, H; Mirzajani, F; Yamini, Y | 1 |
| Huang, Q; Peng, X; Wang, C; Wang, Z; Yu, Y; Zhang, K | 1 |
| Kelly, DE; Kelly, SL; Parker, JE; Warrilow, AG | 1 |
| Cabrito, TR; Chibana, H; Costa, C; Ohno, M; Pires, C; Renaudin, A; Sá-Correia, I; Teixeira, MC | 1 |
| Aguilera, RJ; Martínez, A; Robles-Escajeda, E; Sánchez-Delgado, RA; Varela-Ramirez, A | 1 |
| Basukala, SM; Jha, AK; Kharel, CB; Pathak, DT; Shrestha, S | 1 |
| Cassano, R; Cavalcanti, P; Ferrarelli, T; Mauro, MV; Picci, N; Trombino, S | 1 |
| Casado, J; Cela, R; Ramil, M; Rodríguez, I | 1 |
| Bakhoya, VN; Ojo, OA; Okokon, EO; Ruotsalainen, JH; Verbeek, JH | 1 |
| Kazempour, N; Mahboubi, M | 1 |
| Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AG | 1 |
| Holman, TR; Hughes, DD; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Rolley, NJ; Smyrniotis, CJ; Thoss, V; Warrilow, AG | 1 |
| Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AGS; Wiederhold, NP | 1 |
| Balamurugan, K; Iyer, PM; Pandian, SK; Subramenium, GA; Swetha, TK | 1 |
| Hay, RJ; Jemec, GBE; Saunte, DML; Taudorf, EH | 1 |
| Elgaard, C; Kretschmann, AC; Munkboel, CH; Olesen, MK; Rasmussen, TB; Styrishave, B | 1 |
| Harada, K; Inagaki, K; Kampirapap, K; Koga, H; Maeda, J; Makimura, K; Nanjoh, Y; Neki, D; Reangchainam, S; Tsuboi, R; Yuasa, K | 1 |
| Abou El-Alamin, MM; Aboul-Enein, HY; Atia, MA; Sultan, MA | 1 |
| Chen, J; Dou, T; Ge, G; Liu, K; Meng, Q; Sun, H; Wang, C; Wang, D; Wu, J; Zhao, S; Zhao, T | 1 |
| Borba-Santos, LP; de Almeida Celestino, J; de Almeida Pimentel, G; de Azevedo-França, JA; de Menezes, EF; de Souza, W; Dos Santos, NP; Ferreira, AMDC; Franco, CHJ; Navarro, M; Rozental, S; Souza, C; Vieira, EG | 1 |
| Niemissalo, SM; Pihlaja, TLM; Sikanen, TM | 1 |
| Abastabar, M; Aghili, SR; Badali, H; Haghani, I; Hedayati, MT; Javidnia, J; Khojasteh, S; Meis, JF; Moazeni, M; Nargesi, S; Nosratabadi, M; Shabanzadeh, S; Shokohi, T; Zaedi, A | 1 |
| da Silva Dos Reis Condé, CA; de Andrade Querino, AL; Navarro, M; Silva, H | 1 |
22 review(s) available for ketoconazole and clotrimazole
| Article | Year |
|---|---|
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy.
Topics: 14-alpha Demethylase Inhibitors; Antiprotozoal Agents; Azoles; Humans; Leishmania; Molecular Structure; Sterol 14-Demethylase | 2017 |
Tetrazole hybrids and their antifungal activities.
Topics: Animals; Antifungal Agents; Azoles; Fungi; Humans; Mycoses; Pyridines; Pyrimidines; Quinolines; Structure-Activity Relationship; Tetrazoles | 2019 |
Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Development; Heme; Humans; Hydrophobic and Hydrophilic Interactions; Protein Binding | 2019 |
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
An epigrammatic status of the '
Topics: | 2020 |
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment and developmental therapeutics in aspergillosis. 2. Azoles and other antifungal drugs.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Azoles; Clotrimazole; Disease Models, Animal; Fluconazole; Humans; Imidazoles; Ketoconazole; Lung Diseases, Fungal; Miconazole; Otitis Externa | 1992 |
[Imidazole preparations in mycology].
Topics: Animals; Antifungal Agents; Candidiasis; Clotrimazole; Coccidioidomycosis; Cryptococcosis; Dermatomycoses; Dosage Forms; Drug Therapy, Combination; Humans; Imidazoles; Ketoconazole; Mice; Miconazole; Mycoses; Neoplasms | 1984 |
[Action mechanism and resistance of drugs used in visceral mycoses].
Topics: Animals; Antifungal Agents; Candida albicans; Chemical Phenomena; Chemistry; Clotrimazole; Drug Resistance, Microbial; Flucytosine; Humans; Imidazoles; Ketoconazole; Mice; Mycoses; Piperazines | 1980 |
Treatment of oropharyngeal candidiasis in HIV-positive patients.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Oral; CD4-Positive T-Lymphocytes; Clotrimazole; Fluconazole; HIV Infections; Humans; Ketoconazole; Leukocyte Count; Nystatin; Risk Factors | 1994 |
Pharmacoeconomic analysis of topical treatments for tinea infections.
Topics: Administration, Topical; Adult; Antifungal Agents; Ciclopirox; Clinical Trials as Topic; Clotrimazole; Drug Costs; Economics, Pharmaceutical; Humans; Ketoconazole; Pyridones; Tinea; Treatment Outcome | 1995 |
Treatment of recurrent vulvovaginal candidiasis.
Topics: Antifungal Agents; Boric Acids; Candidiasis, Vulvovaginal; Clotrimazole; Drug Interactions; Female; Fluconazole; Humans; Ketoconazole; Patient Education as Topic; Recurrence; Risk Factors; Teaching Materials; Time Factors; Triazoles | 2000 |
Antimycotic agents in oral candidosis: an overview: 2. Treatment of oral candidosis.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Clotrimazole; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Nystatin; Virulence | 2000 |
A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candidiasis; Candidiasis, Oral; Clotrimazole; Databases as Topic; Fluconazole; HIV Seropositivity; Humans; Itraconazole; Ketoconazole; Nystatin; Oropharynx; Pharyngeal Diseases; Randomized Controlled Trials as Topic; Research Design; Statistics as Topic; Treatment Outcome | 2001 |
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
Topics: Antifungal Agents; Candidiasis, Oral; Clotrimazole; Humans; Ketoconazole; Neoplasms; Randomized Controlled Trials as Topic | 2002 |
Oral candidal infections and antimycotics.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Infective Agents, Local; Antifungal Agents; Candida; Candidiasis, Oral; Chlorhexidine; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Immunocompromised Host; Itraconazole; Ketoconazole; Miconazole; Mouth; Nystatin; Opportunistic Infections; Saliva; Treatment Failure; Triazoles | 2000 |
Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects.
Topics: Animals; Antifungal Agents; Clotrimazole; Drug Resistance, Fungal; Econazole; Fluconazole; Flucytosine; Griseofulvin; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Naphthalenes; Natamycin; Nystatin; Terbinafine; Thiabendazole; Tolnaftate; Veterinary Drugs | 2003 |
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
Topics: Antifungal Agents; Candidiasis, Oral; Clotrimazole; Humans; Ketoconazole; Neoplasms; Randomized Controlled Trials as Topic | 2004 |
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
Topics: Antifungal Agents; Candidiasis, Oral; Clotrimazole; Humans; Ketoconazole; Neoplasms; Randomized Controlled Trials as Topic | 2007 |
Topical antifungals for seborrhoeic dermatitis.
Topics: Adolescent; Adult; Antifungal Agents; Ciclopirox; Clotrimazole; Dermatitis, Seborrheic; Facial Dermatoses; Humans; Ketoconazole; Lithium Compounds; Miconazole; Pyridones; Randomized Controlled Trials as Topic; Scalp Dermatoses; Solanum; Steroids | 2015 |
Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Cutaneous; Clotrimazole; Drug Therapy, Combination; Evidence-Based Medicine; Fluconazole; Humans; Ketoconazole; Miconazole; Nystatin | 2019 |
15 trial(s) available for ketoconazole and clotrimazole
| Article | Year |
|---|---|
Treatment of vaginal candidosis: a comparative study of the efficacy and acceptability of itraconazole and clotrimazole.
Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Itraconazole; Ketoconazole; Patient Acceptance of Health Care; Patient Compliance; Single-Blind Method | 1992 |
The value of chronic suppressive therapy with itraconazole versus clotrimazole in women with recurrent vaginal candidiasis.
Topics: Administration, Oral; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Itraconazole; Ketoconazole; Middle Aged; Prospective Studies; Recurrence; Treatment Outcome | 1992 |
Comparison of topical fungicides in women suffering from vulvovaginitis.
Topics: Administration, Intravaginal; Administration, Oral; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Ketoconazole | 1991 |
Randomized controlled trial of clotrimazole troche and ketoconazole for oropharyngeal candidiasis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Candidiasis; Clinical Trials as Topic; Clotrimazole; Female; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Oropharynx; Pharyngeal Diseases; Random Allocation | 1988 |
Treatment and prevention of oropharyngeal candidiasis.
Topics: Adolescent; Adult; Aged; Aspergillosis; Candidiasis; Child; Child, Preschool; Clinical Trials as Topic; Clotrimazole; Drug Synergism; Half-Life; Humans; Infant; Ketoconazole; Middle Aged; Neoplasms; Pharyngeal Diseases; Placebos; Suppositories; Tablets; Warfarin | 1984 |
A single-blind comparison of oral and intravaginal treatments in acute and recurrent vaginal candidosis in general practice.
Topics: Administration, Oral; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Female; Humans; Imidazoles; Ketoconazole; Random Allocation; Suppositories; Vagina | 1984 |
Single blind comparison of ketoconazole 200 mg oral tablets and clotrimazole 100 mg vaginal tablets and 1% cream in treating acute vaginal candidosis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Female; Humans; Imidazoles; Ketoconazole; Middle Aged; Ointments; Patient Acceptance of Health Care; Tablets | 1984 |
Initial management of recurrent vulvovaginal candidiasis with oral ketoconazole and topical clotrimazole.
Topics: Acute Disease; Administration, Intravaginal; Administration, Oral; Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Female; Follow-Up Studies; Humans; Ketoconazole; Recurrence; Remission Induction; Treatment Failure | 1994 |
Double-blind comparative examination of ketoconazole 1% cream and clotrimazole 2% ointment in superficial dermatomycosis.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Clotrimazole; Dermatomycoses; Double-Blind Method; Female; Humans; Ketoconazole; Male; Middle Aged; Ointments | 1993 |
Routine prophylactic antifungal agents (clotrimazole, ketoconazole, and nystatin) in nontransplant/nonburned critically ill surgical and trauma patients.
Topics: Aged; Candida; Candidiasis; Clotrimazole; Colony Count, Microbial; Critical Illness; Cross Infection; Female; Fungemia; Humans; Incidence; Intensive Care Units; Ketoconazole; Length of Stay; Logistic Models; Male; Middle Aged; Multiple Trauma; Nystatin; Postoperative Complications; Premedication; Prospective Studies; Risk Factors; Severity of Illness Index | 1994 |
Placebo-controlled trial of itraconazole for treatment of acute vaginal candidiasis.
Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Double-Blind Method; Female; Humans; Itraconazole; Ketoconazole | 1993 |
Lack of in vitro resistance of Candida albicans to ketoconazole, itraconazole and clotrimazole in women treated for recurrent vaginal candidiasis.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Clotrimazole; Drug Resistance; Female; Humans; Itraconazole; Ketoconazole; Middle Aged; Prospective Studies; Recurrence | 1993 |
Topical treatment of dermatophytosis and cutaneous candidosis with flutrimazole 1% cream: double-blind, randomized comparative trial with ketoconazole 2% cream.
Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Candidiasis, Cutaneous; Clotrimazole; Dermatomycoses; Double-Blind Method; Female; Humans; Ketoconazole; Male; Middle Aged; Ointments; Treatment Outcome | 1999 |
Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis.
Topics: Adolescent; Adult; Antifungal Agents; Clotrimazole; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epidermophyton; Humans; Ketoconazole; Middle Aged; Ointments; Tinea Pedis | 2002 |
Flutrimazole shampoo 1% versus ketoconazole shampoo 2% in the treatment of pityriasis versicolor. A randomised double-blind comparative trial.
Topics: Adult; Antifungal Agents; Clotrimazole; Double-Blind Method; Female; Hair Preparations; Humans; Ketoconazole; Malassezia; Male; Tinea Versicolor; Treatment Outcome | 2007 |
177 other study(ies) available for ketoconazole and clotrimazole
| Article | Year |
|---|---|
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.
Topics: Cholesterol; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Host-Pathogen Interactions; Humans; Hydroxylation; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Structure, Tertiary | 2010 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity.
Topics: Antifungal Agents; Candida; Carbon-13 Magnetic Resonance Spectroscopy; Drug Screening Assays, Antitumor; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Proton Magnetic Resonance Spectroscopy; Quantitative Structure-Activity Relationship; Thiazolidines | 2017 |
The synthesis, antifungal and apoptotic effects of triazole-oxadiazoles against Candida species.
Topics: Antifungal Agents; Candida; Candidiasis; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Triazoles | 2018 |
Structural features of imidazole derivatives that enhance styrene oxide hydrolase activity in rat hepatic microsomes.
Topics: Animals; Antifungal Agents; Enzyme Activation; Epoxide Hydrolases; Imidazoles; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1985 |
Synthesis of (E)-1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone hydrochloride, a novel, orally active antifungal agent.
Topics: Animals; Antifungal Agents; Candida albicans; Female; Guinea Pigs; Imidazoles; Ketoconazole; Lethal Dose 50; Male; Mice; Miconazole; Piperazines; Rats; Rats, Inbred Strains | 1983 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine | 2002 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship | 2003 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth.
Topics: Antifungal Agents; Candida glabrata; Candidiasis; DNA Primers; Genes, Fungal; Genetic Complementation Test; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation, Missense; Phenotype; Polyenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Fungal; RNA, Messenger; Sterols | 2007 |
Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand.
Topics: Anti-Bacterial Agents; Antifungal Agents; Cadmium; Chelating Agents; Disk Diffusion Antimicrobial Tests; Ferrous Compounds; Ligands; Magnetic Resonance Spectroscopy; Metals, Heavy; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Organomercury Compounds; Organometallic Compounds; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Structure-Activity Relationship; Zinc | 2007 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
Multiple sequential steps involved in the binding of inhibitors to cytochrome P450 3A4.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Kinetics; Ligands; Models, Chemical; Pharmaceutical Preparations; Protein Binding; Recombinant Proteins; Spectrum Analysis; Thermodynamics; Titrimetry | 2007 |
Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex.
Topics: Anti-Infective Agents; Bacteria; Disk Diffusion Antimicrobial Tests; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Organometallic Compounds; Palladium; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spectrum Analysis, Raman; Yeasts | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Treatment of a clinically relevant plant-pathogenic fungus with an agricultural azole causes cross-resistance to medical azoles and potentiates caspofungin efficacy.
Topics: Amphotericin B; Antifungal Agents; Azoles; Caspofungin; Colletotrichum; Drug Resistance, Fungal; Drug Synergism; Echinocandins; Fungi; Fungicides, Industrial; Humans; In Vitro Techniques; Lipopeptides; Microbial Sensitivity Tests; Microscopy, Fluorescence; Nystatin; Plant Diseases; Skin; Triazoles | 2007 |
Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds.
Topics: Anti-Infective Agents; Aza Compounds; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Ligands; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spectrum Analysis, Raman | 2009 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
Topics: Antifungal Agents; Azoles; Base Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Fungal; Drug Resistance, Fungal; Genes, Fungal; Humans; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Species Specificity; Sterol 14-Demethylase | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.
Topics: Amino Acid Motifs; Amino Acid Sequence; Azoles; Base Sequence; Cloning, Molecular; Conserved Sequence; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Genes, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Structure; Molecular Weight; Mycobacterium leprae; Mycobacterium smegmatis; Osmolar Concentration; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Chloride | 2009 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth.
Topics: Adult; Aerobiosis; Antifungal Agents; Azoles; Candida glabrata; Chromatography, High Pressure Liquid; Ergosterol; Female; Flow Cytometry; Genes, Fungal; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Molecular Sequence Data; Polyenes | 2009 |
Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Apoptosis; Bacteria; Cattle; Cell Line, Tumor; DNA; Humans; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Yeasts | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives.
Topics: Antifungal Agents; Candida; Dose-Response Relationship, Drug; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Pyridines; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2010 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Drug Resistance, Fungal; Fungal Proteins; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Anti-Candida activity and cytotoxicity of a large library of new N-substituted-1,3-thiazolidin-4-one derivatives.
Topics: 14-alpha Demethylase Inhibitors; Anti-Bacterial Agents; Antifungal Agents; Candida; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; Fungal Proteins; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Small Molecule Libraries; Sterol 14-Demethylase; Structure-Activity Relationship; Thiazolidines | 2016 |
Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties.
Topics: Antifungal Agents; Antioxidants; Candida; Chelating Agents; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Thiazolidines; Toxicity Tests | 2016 |
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries | 2017 |
Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles.
Topics: Antifungal Agents; Azoles; Candida; Cell Survival; Coumarins; Dose-Response Relationship, Drug; HEK293 Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Optical Imaging; Structure-Activity Relationship | 2019 |
Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Breast Neoplasms; Cell Cycle; Cell Division; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Humans; Ketoconazole; Neoplasms, Hormone-Dependent; Tumor Cells, Cultured | 1992 |
Oral candidosis. Clinical, historical, and therapeutic features of 100 cases.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Oral; Chlorhexidine; Clotrimazole; Female; Humans; Ketoconazole; Male; Middle Aged; Mouthwashes; Nystatin | 1992 |
[In vitro antifungal activity of itraconazole, a new triazole antifungal agent, against clinical isolates from patients with dermatomycoses].
Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Dermatomycoses; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests | 1991 |
Juvenile tinea capitis caused by Trichophyton violaceum. Hepatic reactions during ketoconazole treatment.
Topics: Chemical and Drug Induced Liver Injury; Child; Clotrimazole; Humans; Ketoconazole; Liver Diseases; Male; Scandinavian and Nordic Countries; Tinea Capitis; Trichophyton | 1991 |
Sensitivity of Trichophyton mentagrophytes strains to three imidazole drugs.
Topics: Clotrimazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Trichophyton | 1991 |
Madura foot: a surgical cure.
Topics: Clotrimazole; Humans; Ketoconazole; Mycetoma | 1991 |
Treatment of refractory oral candidiasis with fluconazole. A case report.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Candida albicans; Candidiasis, Oral; Clotrimazole; Deglutition Disorders; Drug Resistance, Microbial; Esophageal Diseases; Fluconazole; Humans; Ketoconazole; Male | 1991 |
Azole susceptibility and hyphal formation in a cytochrome P-450-deficient mutant of Candida albicans.
Topics: Azoles; Candida albicans; Clotrimazole; Cytochrome P-450 Enzyme System; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mutation; Nystatin | 1990 |
In vitro activity of five antifungal agents against Malassezia pachydermatis.
Topics: Animals; Antifungal Agents; Clotrimazole; Dog Diseases; Dogs; Humans; Ketoconazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Natamycin; Nystatin; Otitis Externa | 1990 |
Ketoconazole-resistant mutants of Microsporum gypseum. II. Characteristics of mutants.
Topics: Clotrimazole; Drug Resistance, Microbial; Ergosterol; Ketoconazole; Miconazole; Microsporum; Mutation | 1989 |
Antifungal agents.
Topics: Antifungal Agents; Clotrimazole; Dental Care; Humans; Ketoconazole; Miconazole; Nystatin | 1989 |
Adverse reactions of imidazole antifungal agents: computer graphic studies of cytochrome P-450 interactions.
Topics: Animals; Antifungal Agents; Clotrimazole; Computer Graphics; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Ketoconazole; Miconazole; Mixed Function Oxygenases; Models, Molecular; Protein Binding; Rats | 1989 |
[Effect of synthetic antifungal drugs on the adherence of Candida albicans to the mouth mucosa epithelium in vitro].
Topics: Adhesiveness; Candida albicans; Clotrimazole; Epithelium; Female; Flucytosine; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Mouth Mucosa | 1989 |
Coinduction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents.
Topics: Animals; Clotrimazole; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Imidazoles; Isoenzymes; Ketoconazole; Liver; Miconazole; Rats; Rats, Inbred Strains; RNA, Messenger; Troleandomycin | 1989 |
Sensitivity of some strains of the genus Epidermophyton to different antifungal agents.
Topics: Antifungal Agents; Clotrimazole; Econazole; Epidermophyton; Griseofulvin; Imidazoles; Ketoconazole; Miconazole; Natamycin; Nystatin | 1989 |
Effects of azole antifungals in vitro on host/parasite interactions relevant to Candida infections.
Topics: Antifungal Agents; Candida albicans; Cell Adhesion; Clotrimazole; Female; Fluconazole; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Neutrophils; Phagocytosis; Triazoles; Vagina | 1988 |
Tinea versicolor of the face in black children in a temperate region.
Topics: Black People; Child; Clotrimazole; Diagnosis, Differential; Facial Dermatoses; Humans; Ketoconazole; Male; Ohio; Sebum; Tinea Versicolor; Weather | 1989 |
Effects of imidazole- and triazole-derivative antifungal compounds on the growth and morphological development of Candida albicans hyphae.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Clotrimazole; Flucytosine; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Triazoles | 1985 |
New and prospective developments in antifungal drugs.
Topics: Administration, Oral; Administration, Topical; Allylamine; Antifungal Agents; Clotrimazole; Dermatomycoses; Drug Compounding; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Naphthalenes; Terbinafine; Triazoles | 1986 |
[Comparative action of 8 azole derivatives against Candida albicans: fungistatic action and cytologic study by scanning electron microscopy].
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Cytoplasm; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Spheroplasts; Triazoles | 1988 |
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Indomethacin; Ketoconazole; Male; Masoprocol; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains | 1988 |
[Incidence of mycotic infections in children with acute myeloblastic leukemia (AML)].
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Child; Clotrimazole; Drug Resistance, Microbial; Female; Flucytosine; Humans; Ketoconazole; Leukemia, Myeloid, Acute; Male; Miconazole; Nystatin | 1988 |
Management of combined bacterial and fungal foot infection in coal miners.
Topics: Bacterial Infections; Clotrimazole; Coal Mining; Dermatomycoses; Foot Dermatoses; Humans; Ketoconazole; Male; Occupational Diseases; Povidone-Iodine | 1988 |
Antifungal susceptibility testing of Trichosporon beigelii to imidazole compounds.
Topics: Amphotericin B; Clotrimazole; Culture Media; Econazole; Genital Diseases, Male; Hair; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Mycoses; Piedra; Scrotum; Trichosporon | 1988 |
Inhibition of bovine adrenocortical mitochondrial cytochrome P-450(11)beta-mediated reactions by imidazole derivatives and mineralocorticoid analogs.
Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Clotrimazole; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Etomidate; Imidazoles; Ketoconazole; Miconazole; Mineralocorticoids; Mitochondria | 1988 |
Inhibition of human hepatic and placental xenobiotic monooxygenases by imidazole antimycotics.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Clotrimazole; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Kinetics; Male; Miconazole; Microsomes, Liver; Oxidoreductases; Oxygenases; Placenta; Rats; Rats, Inbred Strains | 1988 |
Combined effects of hyperbaric oxygen and antifungal agents on the growth of Candida albicans.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Clotrimazole; Flucytosine; Hyperbaric Oxygenation; Ketoconazole; Miconazole; Nystatin; Time Factors | 1987 |
Induction of the rat hepatic microsomal mixed-function oxidases by 3 imidazole-containing antifungal agents: selectivity for the cytochrome P-450IIB and P-450III families of cytochromes P-450.
Topics: Animals; Clotrimazole; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Induction; Erythromycin; Imidazoles; Ketoconazole; Male; Miconazole; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains | 1988 |
Activity of terbinafine in experimental fungal infections of laboratory animals.
Topics: Animals; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Dermatomycoses; Female; Guinea Pigs; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mycoses; Naphthalenes; Terbinafine | 1987 |
Comparative study of local and oral treatment of vaginal candidiasis (Canesten-Nizoral).
Topics: Administration, Intravaginal; Administration, Oral; Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Imidazoles; Ketoconazole | 1987 |
Treatment of vaginal discharge caused by blastomycetes with nizoral tablet.
Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Ketoconazole; Leukorrhea; Middle Aged; Mitosporic Fungi; Mycoses; Vaginitis | 1986 |
In vitro assessment of antifungal drug resistance.
Topics: Antifungal Agents; Clotrimazole; Drug Resistance, Microbial; Fungi; Griseofulvin; Imidazoles; In Vitro Techniques; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Triazoles | 1986 |
Interactions of imidazole antifungal agents with purified cytochrome P-450 proteins.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Clotrimazole; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Imidazoles; Ketoconazole; Male; Miconazole; Oxidoreductases; Oxygenases; Rats; Spectrum Analysis | 1987 |
Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans.
Topics: Allylamine; Animals; Antifungal Agents; Candida albicans; Cell Membrane; Cerulenin; Cholestadienols; Chromatography, Gas; Chromatography, Thin Layer; Clotrimazole; Culture Techniques; Econazole; Ergosterol; Fatty Acids; Ketoconazole; Lipids; Miconazole; Tolnaftate | 1987 |
Induction of hepatic oxidative and conjugative drug metabolism in the hamster by N-substituted imidazoles.
Topics: Animals; Body Weight; Clotrimazole; Cricetinae; Cytochrome P-450 Enzyme System; Female; Glucuronates; Imidazoles; Ketoconazole; Male; Mesocricetus; Miconazole; Microsomes, Liver; Organ Size; Oxidation-Reduction; Phenobarbital; Sex Factors | 1987 |
Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells.
Topics: Cell Line; Clotrimazole; Embryonal Carcinoma Stem Cells; Imidazoles; Ketoconazole; Metyrapone; Miconazole; Neoplastic Stem Cells; Tretinoin | 1987 |
Antifungal activity of the allylamine derivative terbinafine in vitro.
Topics: Agar; Antifungal Agents; Arthrodermataceae; Candida; Clotrimazole; Econazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Species Specificity; Terbinafine | 1987 |
Human hair follicle benzo[a]pyrene and benzo[a]pyrene 7,8-diol metabolism: effect of exposure to a coal tar-containing shampoo.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Carbon Monoxide; Clotrimazole; Coal Tar; Dihydroxydihydrobenzopyrenes; DNA; Drug Interactions; Enzyme Induction; Hair; Hair Preparations; Humans; Ketoconazole; NADP | 1987 |
In vitro sensitivity of Malassezia spp. to various antimycotics.
Topics: Amphotericin B; Animals; Antifungal Agents; Clotrimazole; Dog Diseases; Dogs; Econazole; Humans; Ketoconazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Nystatin; Otitis; Tinea Versicolor | 1985 |
Antifungal drugs affecting the chemotaxis of polymorphonuclear neutrophils.
Topics: Antifungal Agents; Cell Extracts; Chemotaxis, Leukocyte; Clotrimazole; Complement System Proteins; Econazole; Griseofulvin; Humans; Ketoconazole; Miconazole; Natamycin; Neutrophils; Trichophyton | 1985 |
Inhibition of rat liver microsomal cytochrome P-450 steroid hydroxylase reactions by imidazole antimycotic agents.
Topics: Androstenedione; Animals; Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Imidazoles; Ketoconazole; Male; Miconazole; Microsomes, Liver; Rats; Steroid Hydroxylases | 1986 |
Do the imidazoles have a role in the management of genitourinary fungal infections?
Topics: Adult; Aged; Candidiasis; Clotrimazole; Female; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Middle Aged; Time Factors; Urinary Tract Infections | 1985 |
Classification and pathogenesis of vulvovaginal candidiasis.
Topics: Anti-Bacterial Agents; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Ketoconazole; Risk; Vagina | 1985 |
The interaction of representative members from two classes of antimycotics--the azoles and the allylamines--with cytochromes P-450 in steroidogenic tissues and liver.
Topics: Adrenal Glands; Allylamine; Amines; Animals; Antifungal Agents; Azoles; Cattle; Clotrimazole; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Humans; In Vitro Techniques; Ketoconazole; Liver; Male; Mice; Miconazole; Microsomes, Liver; Naphthalenes; Placenta; Protein Binding; Rats; Spectrophotometry; Terbinafine; Testis | 1985 |
Scytalidium hyalinum infection diagnosed in Spain.
Topics: Adult; Africa, Central; Clotrimazole; Dermatomycoses; Foot Dermatoses; Humans; Ketoconazole; Male; Mitosporic Fungi; Spain | 1984 |
Modification of polymorphonuclear leucocyte function by imidazoles.
Topics: Blood Bactericidal Activity; Candida; Chemotaxis, Leukocyte; Clotrimazole; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Miconazole; Neutrophils; Tinidazole | 1984 |
Broth dilution and disc diffusion methods in the susceptibility testing of pathogenic Candida albicans against four antimycotics.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Chlorhexidine; Clotrimazole; Drug Resistance, Microbial; Flucytosine; Humans; Ketoconazole; Microbial Sensitivity Tests; Mouth; Stomatitis | 1984 |
Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents.
Topics: Antifungal Agents; Aspergillus; Candida; Clotrimazole; Econazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Miconazole; Morpholines; Triazoles | 1984 |
Infantile epidermodysplastic erythema gyratum responsive to imidazoles. A new entity?
Topics: Child, Preschool; Clotrimazole; Dermatomycoses; Erythema; Female; Humans; Infant; Ketoconazole; Miconazole; Skin | 1984 |
Ketoconazole binds to glucocorticoid receptors and exhibits glucocorticoid antagonist activity in cultured cells.
Topics: Animals; Antifungal Agents; Carcinoma, Hepatocellular; Cells, Cultured; Clotrimazole; Dexamethasone; Humans; Imidazoles; Ketoconazole; Liver Neoplasms; Piperazines; Rats; Receptors, Glucocorticoid; Receptors, Steroid; Tyrosine Transaminase | 1983 |
Activity of imidazoles against Leishmania tropica in human macrophage cultures.
Topics: Clotrimazole; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Leishmania; Leishmaniasis; Macrophages; Miconazole; Piperazines | 1981 |
Inhibition and induction of microsomal enzymes in rat. A comparative study of four antimycotics: miconazole, econazole, clotrimazole and ketoconazole.
Topics: Animals; Antifungal Agents; Clotrimazole; Econazole; Enzyme Induction; Enzyme Inhibitors; Imidazoles; Ketoconazole; Male; Miconazole; Microsomes, Liver; Pharmaceutical Preparations; Piperazines; Rats | 1981 |
Heterogeneity of action of mechanisms among antimycotic imidazoles.
Topics: Aerobiosis; Anaerobiosis; Antifungal Agents; Clotrimazole; Ergosterol; Imidazoles; Ketoconazole; Lanosterol; Miconazole; Piperazines; Saccharomyces cerevisiae | 1981 |
A comparison of the effects of several antifungal imidazole derivatives and polyenes on Candida albicans: an ultrastructural study by scanning electron microscopy.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Cell Membrane; Cell Wall; Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Microscopy, Electron, Scanning; Nystatin; Piperazines | 1982 |
Therapy of fungal infections.
Topics: Amphotericin B; Animals; Clotrimazole; Dogs; Humans; Imidazoles; Ketoconazole; Miconazole; Mycoses; Piperazines | 1982 |
[Antimycotic therapy. 2. Antimycotic chemotherapeutic agents: imidazole derivatives, tolciclate, haloprogin, ciclopiroxolamin].
Topics: Antifungal Agents; Chemical Phenomena; Chemistry; Ciclopirox; Clotrimazole; Dermatomycoses; Econazole; Humans; Imidazoles; Ketoconazole; Miconazole; Phenyl Ethers; Piperazines; Pyridones; Thiocarbamates | 1983 |
Lyophilized microculture susceptibility test for ketoconazole, miconazole, clotrimazole, and griseofulvin against dermatophytes.
Topics: Antifungal Agents; Clotrimazole; Freeze Drying; Griseofulvin; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Microsporum; Piperazines; Trichophyton | 1983 |
Comparative susceptibility of the agents of adiaspiromycosis to imidazole derivatives in vitro.
Topics: Antifungal Agents; Chrysosporium; Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Mitosporic Fungi; Spores, Fungal | 1983 |
Novel synergism of two antifungal agents, copiamycin and imidazole.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Clotrimazole; Drug Synergism; Fungi; Imidazoles; Ketoconazole; Lactones; Mitochondrial Swelling | 1983 |
Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell-Free System; Clotrimazole; Female; Guinea Pigs; Humans; Imidazoles; Ketoconazole; Lung; Miconazole; Thromboxane B2; Thromboxanes | 1983 |
Chronic mucocutaneous candidiasis.
Topics: Candidiasis; Candidiasis, Chronic Mucocutaneous; Candidiasis, Oral; Clotrimazole; Humans; Infant; Ketoconazole; Male | 1983 |
An experimental model for evaluation of antifungal agents in a Trichophyton mentagrophytes infection of guinea pigs.
Topics: Animals; Antifungal Agents; Clotrimazole; Disease Models, Animal; Female; Griseofulvin; Guinea Pigs; Ketoconazole; Microbial Sensitivity Tests; Time Factors; Tinea | 1984 |
The effect of imidazoles on germination of arthrospores and microconidia of Trichophyton mentagrophytes.
Topics: Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Spores, Fungal; Trichophyton | 1984 |
Cutaneous leishmaniasis: failure of topical treatment with imidazole derivatives in laboratory animals and man.
Topics: Administration, Topical; Animals; Clotrimazole; Humans; Imidazoles; Ketoconazole; Leishmaniasis; Mice; Miconazole | 1984 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine | 1995 |
Efficacy of 6-amino-2-n-pentylthiobenzothiazole on Trichophyton in vitro and in vivo.
Topics: Animals; Antifungal Agents; Benzothiazoles; Clotrimazole; Guinea Pigs; Ketoconazole; Microbial Sensitivity Tests; Thiazoles; Tinea; Trichophyton | 1995 |
Cloning and stable expression of the human mitochondrial cytochrome P45011B1 cDNA in V79 Chinese hamster cells and their application for testing of potential inhibitors.
Topics: Adrenal Glands; Animals; Base Sequence; Cell Line; Cloning, Molecular; Clotrimazole; Cricetinae; Cricetulus; DNA Primers; DNA, Complementary; Fluconazole; Gene Expression; Hydrocortisone; Hydroxylation; Ketoconazole; Kinetics; Metyrapone; Miconazole; Mitochondria; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Spironolactone; Steroid 11-beta-Hydroxylase; Transfection | 1995 |
The dual mode of inhibition of calmodulin-dependent nitric-oxide synthase by antifungal imidazole agents.
Topics: Amino Acid Oxidoreductases; Animals; Antifungal Agents; Biopterins; Brain; Calmodulin; Cattle; Citrulline; Clotrimazole; Imidazoles; Ketoconazole; Kinetics; Miconazole; NADH Dehydrogenase; Nitric Oxide Synthase; Pituitary Neoplasms; Rats; Tumor Cells, Cultured | 1993 |
Antifungal effects of Allium sativum (garlic) extract against the Aspergillus species involved in otomycosis.
Topics: Aspergillus fumigatus; Aspergillus nidulans; Aspergillus niger; Clotrimazole; Garlic; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Otitis Externa; Plant Extracts; Plant Oils; Plants, Medicinal | 1995 |
Regulated production and intracrine action of 1,25-dihydroxyvitamin D3 in the chick myelomonocytic cell line HD-11.
Topics: Animals; Calcifediol; Calcitriol; Calcium; Cell Division; Cell Line, Transformed; Chickens; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Genes, myc; Granulocytes; Hydroxylation; Insulin-Like Growth Factor I; Interferon-gamma; Ketoconazole; Lipopolysaccharides; Monocytes; Phosphates; Vitamin K | 1994 |
Dermatophytosis of children in Kuwait: a prospective survey.
Topics: Animals; Animals, Domestic; Child; Child, Preschool; Clotrimazole; Dermatomycoses; Drug Therapy, Combination; Family Health; Female; Griseofulvin; Humans; Infant; Ketoconazole; Kuwait; Male; Microsporum; Prospective Studies; Tinea; Tinea Capitis; Treatment Outcome; Trichophyton | 1993 |
Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity.
Topics: Antifungal Agents; Calmodulin; Clotrimazole; Drug Interactions; Econazole; Imidazoles; Ketoconazole; Kinetics; Miconazole; Phosphodiesterase Inhibitors; Polymyxin B | 1993 |
[Polarographic examination of drugs derived from imidazol. I. Clotrimazole and ketoconazole].
Topics: Clotrimazole; Ketoconazole; Polarography; Tablets | 1992 |
Topical anti-inflammatory properties of flutrimazole, a new imidazole antifungal agent.
Topics: Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Antifungal Agents; Arachidonic Acid; Carrageenan; Clotrimazole; Cyclooxygenase Inhibitors; Diclofenac; Edema; Granulocytes; Humans; Ketoconazole; Leukotriene B4; Male; Mice; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme.
Topics: Antifungal Agents; Azoles; Clotrimazole; Genes, Fungal; Genotype; Heme; Itraconazole; Ketoconazole; Lanosterol; Mixed Function Oxygenases; Mutation; Saccharomyces cerevisiae; Sterols; Suppression, Genetic | 1997 |
Imidazole antimycotics affect the activity of various ion channels and insulin secretion in mouse pancreatic B-cells.
Topics: Animals; Antifungal Agents; Clotrimazole; Culture Techniques; Econazole; Electrophysiology; Female; Imidazoles; Insulin; Insulin Secretion; Ion Channels; Islets of Langerhans; Ketoconazole; Mice; Patch-Clamp Techniques | 1997 |
[Effect of imidazole antifungal agents on colony formation by murine bone marrow CFUc (colony forming units in culture].
Topics: Animals; Antifungal Agents; Bone Marrow Cells; Cells, Cultured; Clotrimazole; Colony-Forming Units Assay; Econazole; Hematopoietic Stem Cells; Humans; Imidazoles; Ketoconazole; Mice; Miconazole | 1996 |
Nondermatologists are more likely than dermatologists to prescribe antifungal/corticosteroid products: an analysis of office visits for cutaneous fungal infections, 1990-1994.
Topics: Administration, Topical; Ambulatory Care; Anti-Inflammatory Agents; Antifungal Agents; Betamethasone; Clotrimazole; Cost Savings; Cost-Benefit Analysis; Dermatology; Dermatomycoses; Drug Combinations; Drug Costs; Family Practice; Glucocorticoids; Humans; Ketoconazole; Office Visits; Pediatrics; Practice Patterns, Physicians'; Tinea; Treatment Outcome | 1998 |
Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.
Topics: Azepines; Benzimidazoles; Calcium; Cell Line; Charybdotoxin; Chromosome Mapping; Chromosomes, Human, Pair 19; Cloning, Molecular; Clotrimazole; Cnidarian Venoms; Humans; In Situ Hybridization, Fluorescence; Intermediate-Conductance Calcium-Activated Potassium Channels; Ketoconazole; Kidney; Membrane Potentials; Miconazole; Neurotoxins; Nitrendipine; Organ Specificity; Potassium Channels; Potassium Channels, Calcium-Activated; Recombinant Proteins; Scorpion Venoms; Transfection | 1998 |
In vitro susceptibilities of clinical yeast isolates to the new antifungal eberconazole compared with their susceptibilities to clotrimazole and ketoconazole.
Topics: Antifungal Agents; Candida; Clotrimazole; Cryptococcus; Cycloheptanes; Imidazoles; Ketoconazole; Microbial Sensitivity Tests | 1999 |
Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro.
Topics: Animals; Antifungal Agents; Azoles; Bone Marrow; Cells, Cultured; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Female; Fluconazole; Granulocytes; Hematopoietic Stem Cells; Humans; Imidazoles; Inhibitory Concentration 50; Ketoconazole; Macrophages; Male; Mice; Miconazole; Species Specificity; Stem Cells | 1999 |
In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata.
Topics: Antifungal Agents; Azoles; Candida; Candidiasis; Clotrimazole; DNA, Fungal; DNA, Mitochondrial; Drug Resistance, Microbial; Econazole; Electrophoresis, Agar Gel; Fluconazole; Humans; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Polyenes | 1999 |
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels.
Topics: Calcium; Calcium Channel Blockers; Cells, Cultured; Clotrimazole; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Electrochemistry; Enzyme Inhibitors; Growth Inhibitors; Humans; Interferon-gamma; Ketoconazole; Lymphocyte Activation; Nitrendipine; Patch-Clamp Techniques; Phytohemagglutinins; Potassium Channel Blockers; Potassium Channels; T-Lymphocytes; Tetanus Toxin; Time Factors | 1999 |
Oxidation of bilirubin in the brain-further characterization of a potentially protective mechanism.
Topics: Animals; Bilirubin; Brain; Clotrimazole; Cytochrome c Group; Electron Transport Complex IV; Intracellular Membranes; Ketoconazole; Malate Dehydrogenase; Mitochondria; Monoamine Oxidase; Oxidation-Reduction; Potassium Cyanide; Rats; Rats, Sprague-Dawley | 1999 |
Effects of inhibitors of small- and intermediate-conductance calcium-activated potassium channels, inwardly-rectifying potassium channels and Na(+)/K(+) ATPase on EDHF relaxations in the rat hepatic artery.
Topics: Acetylcholine; Alkanes; Animals; Barium; Biological Factors; Calcium; Clotrimazole; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Erythrocytes; Female; Hepatic Artery; Humans; In Vitro Techniques; Indoles; Ketoconazole; Ouabain; Potassium; Potassium Channel Blockers; Potassium Channels; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Scorpion Venoms; Sodium-Potassium-Exchanging ATPase; Tubocurarine; Vasodilation | 2000 |
Amino acid 305 determines catalytic center accessibility in CYP3A4.
Topics: Alanine; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Econazole; Erythromycin; Humans; Imidazoles; Ketoconazole; Kinetics; Miconazole; Mixed Function Oxygenases; Multienzyme Complexes; Mutation; Nifedipine; Oxidoreductases, N-Demethylating; Substrate Specificity; Testosterone | 2000 |
State-dependent block of rabbit vascular smooth muscle delayed rectifier and Kv1.5 channels by inhibitors of cytochrome P450-dependent enzymes.
Topics: Algorithms; Animals; Cells, Cultured; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Ketoconazole; Kv1.5 Potassium Channel; Muscle, Skeletal; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rabbits; Transfection | 2001 |
Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals.
Topics: Acetic Acid; Acetonitriles; Antifungal Agents; Clotrimazole; Drug Stability; Electrophoresis, Capillary; Fluconazole; Humans; Itraconazole; Ketoconazole; Methanol; Microsomes, Liver; Molecular Structure; Molecular Weight; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Triazoles; Verapamil; Voriconazole | 2001 |
Toward a novel metal-based chemotherapy against tropical diseases. 6. Synthesis and characterization of new copper(II) and gold(I) clotrimazole and ketoconazole complexes and evaluation of their activity against Trypanosoma cruzi.
Topics: Algorithms; Animals; Antiprotozoal Agents; Chagas Disease; Chemical Phenomena; Chemistry, Physical; Clotrimazole; Copper; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Gold; Ketoconazole; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Trypanosoma cruzi | 2001 |
[Vulvovaginal candidiasis in childhood--diagnostic and therapeutic results].
Topics: Adolescent; Anti-Bacterial Agents; Antifungal Agents; Bulgaria; Candidiasis, Vulvovaginal; Child; Child, Preschool; Clotrimazole; Female; Humans; Infant; Ketoconazole; Nystatin; Treatment Outcome | 2001 |
Effect of antifungal azoles on the heme detoxification system of malarial parasite.
Topics: Animals; Antifungal Agents; Antimalarials; Clotrimazole; Electron Spin Resonance Spectroscopy; Erythrocytes; Glutathione; Heme; Hemolysis; Humans; In Vitro Techniques; Ketoconazole; Miconazole; Peptides; Plasmodium falciparum; Spectrum Analysis | 2002 |
Comparison of two methods for antifungal susceptibility testing of Trichophyton rubrum.
Topics: Antifungal Agents; Clotrimazole; Culture Media; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Sensitivity and Specificity; Terbinafine; Trichophyton | 2002 |
Triiodide ion and alizarin red S as two new reagents for the determination of clotrimazole and ketoconazole.
Topics: Anthraquinones; Chemistry, Pharmaceutical; Clotrimazole; Iodides; Ketoconazole | 2002 |
Chromatographic determination of clotrimazole, ketoconazole and fluconazole in pharmaceutical formulations.
Topics: Antifungal Agents; Calibration; Capsules; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clotrimazole; Densitometry; Fluconazole; Indicators and Reagents; Ketoconazole; Ointments; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2002 |
Clotrimazole, ketoconazole, and clodinafop-propargyl as potent growth inhibitors of equine Babesia parasites during in vitro culture.
Topics: Alkynes; Animals; Antifungal Agents; Babesia; Babesiosis; Clotrimazole; Equidae; Growth Inhibitors; Herbicides; Horse Diseases; Horses; Ketoconazole; Microscopy, Electron; Propanols; Propionates; Pyridines | 2003 |
In vitro activities of the new antifungal drug eberconazole and three other topical agents against 200 strains of dermatophytes.
Topics: Administration, Topical; Antifungal Agents; Arthrodermataceae; Clotrimazole; Humans; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Species Specificity | 2003 |
Clotrimazole, ketoconazole, and clodinafop-propargyl inhibit the in vitro growth of Babesia bigemina and Babesia bovis (Phylum Apicomplexa).
Topics: Animals; Antiprotozoal Agents; Babesia bovis; Cattle; Clotrimazole; Drug Interactions; Herbicides; Inhibitory Concentration 50; Ketoconazole; Microscopy, Electron; Propionates; Pyridines | 2003 |
[Determination of biological activity of hydrogel preparations based on ketoconazole and clotrimazole].
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Colony Count, Microbial; Hydrogels; Ketoconazole; Staphylococcus aureus | 2004 |
Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Caspase 3; Caspases; Cisplatin; Clotrimazole; Combined Modality Therapy; Cytochromes c; Drug Synergism; Enzyme Activation; ErbB Receptors; Humans; Ketoconazole; Membrane Proteins; Mitochondria; Neoplasms; Poly(ADP-ribose) Polymerases; Ruthenium Compounds; Spheroids, Cellular; Superoxide Dismutase; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2004 |
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.
Topics: Antifungal Agents; Arthrodermataceae; Ascomycota; Clotrimazole; Econazole; Fluconazole; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Terbinafine; Thiophenes | 2004 |
In vitro activities of transition metal derivatives of ketoconazole and clotrimazole against a wild type strain of Saccharomyces cerevisiae in absence or presence of human neutrophils.
Topics: Antifungal Agents; Cell Survival; Clotrimazole; Copper; Gold; Humans; In Vitro Techniques; Ketoconazole; Luminescent Measurements; Metals; Microbial Sensitivity Tests; Neutrophils; Phagocytosis; Ruthenium; Saccharomyces cerevisiae | 2004 |
Increased expression and hotspot mutations of the multidrug efflux transporter, CDR1 in azole-resistant Candida albicans isolates from vaginitis patients.
Topics: Antifungal Agents; Base Sequence; Candida albicans; Candida glabrata; Candidiasis; Clotrimazole; DNA Primers; Drug Resistance, Fungal; Female; Fungal Proteins; Gene Expression Regulation, Fungal; Humans; Ketoconazole; Membrane Transport Proteins; Molecular Sequence Data; Point Mutation; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Vaginitis | 2005 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |
The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents.
Topics: Antifungal Agents; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Clotrimazole; Drug Carriers; Drug Delivery Systems; Drug Storage; Electrochemistry; Hydrogels; Imidazoles; Ketoconazole; Lipids; Nanostructures; Particle Size; Rheology; Temperature; Viscosity | 2006 |
Effect of commonly used herbicides on the virulence factor CDR1 in Candida albicans.
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Fluconazole; Fungal Proteins; Ketoconazole; Membrane Transport Proteins | 2008 |
Screening of antimycotics in Swedish sewage treatment plants--waters and sludge.
Topics: Antifungal Agents; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Naphthalenes; Sewage; Sweden; Terbinafine; Waste Disposal, Fluid; Water Pollutants, Chemical | 2010 |
Use of antifungal agents for oral candidiasis: results of a national survey.
Topics: Administration, Topical; Adult; Antifungal Agents; Attitude of Health Personnel; Candidiasis, Oral; Clotrimazole; Dentists; Female; General Practice, Dental; Humans; Ketoconazole; Male; Miconazole; Nystatin; Oral Medicine; Private Practice; Professional Practice; Public Health Dentistry; Sex Factors; Spain; Stomatitis, Denture; Surveys and Questionnaires; Time Factors | 2010 |
Azole drugs trap cytochrome P450 EryK in alternative conformational states.
Topics: Azoles; Bacterial Proteins; Catalytic Domain; Clotrimazole; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Ketoconazole; Protein Conformation; Saccharopolyspora | 2010 |
Optimization of a novel method based on solidification of floating organic droplet by high-performance liquid chromatography for evaluation of antifungal drugs in biological samples.
Topics: Antifungal Agents; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Clotrimazole; Ketoconazole; Light; Miconazole; Models, Chemical; Organic Chemicals; Solvents; Surface Properties; Temperature; Time Factors; Water Pollutants, Chemical | 2010 |
Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China.
Topics: Antifungal Agents; Azoles; Biodegradation, Environmental; China; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Sewage; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Escherichia coli; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Kinetics; Lanosterol; NADP; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Triazoles; Voriconazole | 2013 |
Candida glabrata drug:H+ antiporter CgQdr2 confers imidazole drug resistance, being activated by transcription factor CgPdr1.
Topics: Antifungal Agents; Antiporters; ATP-Binding Cassette Transporters; Candida glabrata; Clotrimazole; Drug Resistance, Fungal; Gene Expression Regulation, Fungal; Green Fluorescent Proteins; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Transcription Factors | 2013 |
Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Clotrimazole; DNA, Neoplasm; Humans; Ketoconazole; Male; Prostatic Neoplasms; Ruthenium | 2013 |
Ketoconazole or clotrimazole solution wash as a prophylaxis in management and prevention of fungal infection: a comparative study.
Topics: Administration, Topical; Adolescent; Adult; Antifungal Agents; Child; Clotrimazole; Dermatomycoses; Female; Humans; Ketoconazole; Male; Middle Aged; Solutions; Treatment Outcome | 2013 |
Preparation, characterization and in vitro activities evaluation of solid lipid nanoparticles based on PEG-40 stearate for antifungal drugs vaginal delivery.
Topics: Acrylates; Antifungal Agents; Candida albicans; Cell Line; Clotrimazole; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Humans; Ketoconazole; Lipids; Microbial Sensitivity Tests; Nanoparticles; Polyethylene Glycols; Vagina | 2016 |
Identification of antimycotic drugs transformation products upon UV exposure.
Topics: Animals; Antifungal Agents; Clotrimazole; Daphnia; Drug Residues; Environmental Monitoring; Environmental Pollutants; Ketoconazole; Miconazole; Reference Standards; Solvents; Ultraviolet Rays | 2015 |
The anti-candidal activity of Satureja khuzistanica ethanol extract against clinical isolates of C. albicans.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Clotrimazole; Diabetes Complications; Drug Interactions; Female; Humans; Ketoconazole; Male; Microbial Sensitivity Tests; Plant Components, Aerial; Plant Extracts; Satureja; Vagina | 2016 |
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole | 2016 |
Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Cytochrome P450 Family 51; Drug Evaluation, Preclinical; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Kinetics; Lipids; Malassezia; Spectrophotometry; Sterol 14-Demethylase; Sterols; Voriconazole | 2016 |
The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyridines; Sterol 14-Demethylase; Substrate Specificity; Tetrazoles; Trichophyton; Voriconazole | 2017 |
5-hydroxymethyl-2-furaldehyde from marine bacterium Bacillus subtilis inhibits biofilm and virulence of Candida albicans.
Topics: Animals; Antifungal Agents; Bacillus subtilis; Biofilms; Caenorhabditis elegans; Candida albicans; Clotrimazole; Drug Synergism; Ergosterol; Furaldehyde; Hyphae; Ketoconazole; Miconazole; Virulence | 2018 |
The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax.
Topics: Antifungal Agents; Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Clotrimazole; Dose-Response Relationship, Drug; Endocrine Disruptors; Fluconazole; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Ketoconazole; Miconazole; Steroid 17-alpha-Hydroxylase | 2019 |
In vitro antifungal activity of luliconazole against nondermatophytic moulds.
Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Fluconazole; Fungi; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Morpholines; Sequence Analysis, DNA; Terbinafine; Triazoles; Voriconazole | 2020 |
Novel Application of Pentabromobenzyl Column for Simultaneous Determination of Eight Antifungal Drugs Using High-performance Liquid Chromatography.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Humans; Hydrocarbons, Brominated; Imidazoles; Ketoconazole; Liquid-Liquid Extraction; Molecular Structure; Thiophenes; Triazoles; Voriconazole | 2020 |
Comparison of the Inhibitory Effects of Clotrimazole and Ketoconazole against Human Carboxylesterase 2.
Topics: Antifungal Agents; Carboxylesterase; Clotrimazole; Cytochrome P-450 CYP3A; Humans; Ketoconazole; Kinetics; Molecular Docking Simulation | 2021 |
Antifungal promising agents of zinc(II) and copper(II) derivatives based on azole drug.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Coordination Complexes; Copper; Cryptococcus neoformans; Ketoconazole; Microbial Sensitivity Tests; Sporothrix; X-Ray Diffraction; Zinc | 2021 |
Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro.
Topics: Animals; Ciprofloxacin; Clotrimazole; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ketoconazole; Liver; Microsomes, Liver; Oncorhynchus mykiss; Sulfamethoxazole | 2022 |
In vitro activity of 23 antifungal drugs against 54 clinical and environmental Aspergillus oryzae isolates.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Aspergillus oryzae; Clotrimazole; Econazole; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Natamycin; Nystatin; Terbinafine; Tolnaftate; Voriconazole | 2022 |
Silver(I) complexes containing N-heterocyclic carbene azole drugs: Synthesis, characterization, cytotoxic activity, and their BSA interactions.
Topics: Animals; Antineoplastic Agents; Azoles; Clotrimazole; Coordination Complexes; Humans; Ketoconazole; Ligands; Mice; Neoplasms; Pharmaceutical Preparations; Silver | 2023 |