ketoconazole has been researched along with ciprofloxacin in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.92) | 18.2507 |
| 2000's | 14 (26.92) | 29.6817 |
| 2010's | 34 (65.38) | 24.3611 |
| 2020's | 3 (5.77) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Artym, J; Jeleń, M; Kocięba, M; Morak-Młodawska, B; Pluta, K; Zaczyńska, E; Zimecki, M | 1 |
| Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF | 1 |
| Chou, S; Dou, X; Shan, A; Song, J; Wang, J; Wang, Z; Yang, Y; Yang, Z | 1 |
| Chen, YM; Fu, HY; Gao, Y; Hai, P; Ma, BJ; Xiao, JF; Xu, LL; Yang, XL; Zhang, SB | 1 |
| Cao, F; Meng, ZH; Mu, X; Yue, YF; Zhu, HJ | 1 |
| Cushman, M; Fan, BZ; Han, X; Kong, FS; Li, YX; Liang, JH; Lv, W; Ma, CX; Tian, JC | 1 |
| Cushman, M; Fan, BZ; Guo, SY; Kong, FS; Li, XM; Li, YX; Liang, JH; Lv, W; Zhang, J | 1 |
| Gao, F; Huang, G; Xiao, J | 1 |
| Cao, F; Liu, YF; Shao, CL; Wang, CY; Zhang, YH | 1 |
| Lyubina, AP; Mironov, VF; Pashirova, TN; Sapunova, AS; Shaihutdinova, ZM; Tatarinov, DA; Terekhova, NV; Voloshina, AD; Zakharova, LY | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
| Jia, L; Sun, H | 1 |
| Nagendra Mohan, AV; Padmavathi, V; Shazia, A; Thriveni, P | 1 |
| Panneerselvam, P; Ramesh Kumar, N; Rather, BA; Ravi Sankar Reddy, D | 1 |
| el-Gazzar, AB; Hafez, HN; Nawwar, GA | 1 |
| Abedi, D; Bostaki, G; Deilami, O; Fassihi, A; Fazeli, H; Sabet, R; Sadinpour, H; Saghaie, L | 1 |
| Chlipala, G; Krunic, A; Mo, S; Orjala, J | 1 |
| Damodiran, M; Muralidharan, D; Perumal, PT | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Sen, S; Sinha, N | 1 |
| Abdel-Wahab, BF; Awad, GE; Badria, FA | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chikhalia, KH; Kumari, P; Patel, RV; Rajani, DP | 1 |
| Babu, M; Pitchumani, K; Ramesh, P | 1 |
| Kumari, P; Patel, D; Patel, N | 1 |
| Abdel-Wahab, BF; Awad, GE; Khidre, RE | 1 |
| Arun, Y; Balachandran, C; Bhaskar, G; Perumal, PT; Saikumar, C | 1 |
| Abdel-Latif, E; Abdel-Wahab, BF; Awad, GE; Mohamed, HA | 1 |
| Chikhalia, KH; Kumari, P; Patel, PK; Patel, RV; Rajani, DP | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Abbas, SY; Basyouni, WM; El-Gammal, EW; El-Sharief, MA; Fakhr, IM | 1 |
| Bao, L; Cai, L; Chen, JL; Huang, P; Liu, HW; Liu, MM; Qi, QY; Wang, QX; Yang, JL; Yang, XL; Zhang, LX | 1 |
| Abbas, SY; El-Bayouki, KA; El-Gammal, EW; El-Sharief, MA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Cai, G; Cho, S; Franzblau, SG; Jaki, BU; Lee, IA; McAlpine, JB; Napolitano, JG; Pauli, GF; Suh, JW; Wang, Y; Yang, SH | 1 |
| Krishna, NS; Padmaja, A; Padmavathi, V; Reddy, GM; Reddy, PR; Seenaiah, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Camilo, A; de Andrade, AM; de Lazaro, SR; Garcia, JR; Pontes Ribeiro, RA; Reddy, GM; Reddy, VH | 1 |
| Daniel, E; John, D | 1 |
| Damle, BD; Kaul, S; Knupp, C; Mummaneni, V | 1 |
| Abou-Auda, HS; Al-Humayyd, MS; Mustafa, AA | 1 |
| Fahal, AH; Mahgoub, el S; Mhmoud, NA; van de Sande, WW | 1 |
| Daali, Y; Desmeules, JA; Marsousi, N; Rudaz, S | 1 |
| Niemissalo, SM; Pihlaja, TLM; Sikanen, TM | 1 |
4 review(s) available for ketoconazole and ciprofloxacin
| Article | Year |
|---|---|
Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Antipsychotic Agents; Bacteria; Fungi; Humans; Leishmania; Molecular Structure; Neoplasms; Phenothiazines | 2017 |
Recently reported biological activities of pyrazole compounds.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles | 2017 |
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for ketoconazole and ciprofloxacin
| Article | Year |
|---|---|
Lack of effect of simultaneously administered didanosine encapsulated enteric bead formulation (Videx EC) on oral absorption of indinavir, ketoconazole, or ciprofloxacin.
Topics: Absorption; Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Antimetabolites; Capsules; Chemistry, Pharmaceutical; Ciprofloxacin; Cross-Over Studies; Didanosine; Drug Interactions; Drug Tolerance; Female; HIV Protease Inhibitors; Humans; Indinavir; Ketoconazole; Male; Middle Aged | 2002 |
The combination of amoxicillin-clavulanic acid and ketoconazole in the treatment of Madurella mycetomatis eumycetoma and Staphylococcus aureus co-infection.
Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antifungal Agents; Child; Ciprofloxacin; Coinfection; Drug Therapy, Combination; Female; Humans; Ketoconazole; Madurella; Male; Middle Aged; Mycetoma; Prospective Studies; Staphylococcal Infections; Treatment Outcome; Young Adult | 2014 |
46 other study(ies) available for ketoconazole and ciprofloxacin
| Article | Year |
|---|---|
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Combating Drug-Resistant Fungi with Novel Imperfectly Amphipathic Palindromic Peptides.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Candida albicans; Cytoplasm; Drug Resistance, Fungal; HEK293 Cells; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Inverted Repeat Sequences; Mice; Models, Molecular; Peptides; Protein Conformation; RAW 264.7 Cells | 2018 |
Prenylated Indole Diterpene Alkaloids from a Mine-Soil-Derived Tolypocladium sp.
Topics: Anti-Infective Agents; Cell Line, Tumor; Diterpene Alkaloids; Humans; Hypocreales; Indoles; Magnetic Resonance Spectroscopy; Soil Microbiology | 2019 |
Absolute Configuration of Bioactive Azaphilones from the Marine-Derived Fungus Pleosporales sp. CF09-1.
Topics: Ascomycota; Benzopyrans; Circular Dichroism; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Vibrio | 2019 |
Design, synthesis and structure-activity relationships of novel macrolones: Hybrids of 2-fluoro 9-oxime ketolides and carbamoyl quinolones with highly improved activity against resistant pathogens.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Bacterial; Ketolides; Microbial Sensitivity Tests; Molecular Structure; Oximes; Quinolones; Streptococcus pneumoniae; Streptococcus pyogenes; Structure-Activity Relationship | 2019 |
Synthesis and structure-bactericidal activity relationships of non-ketolides: 9-Oxime clarithromycin 11,12-cyclic carbonate featured with three-to eight-atom-length spacers at 3-OH.
Topics: Anti-Bacterial Agents; Bacteria; Clarithromycin; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2019 |
Microketides A and B, Polyketides from a Gorgonian-Derived
Topics: Anti-Bacterial Agents; Antifungal Agents; Ascomycota; China; Magnetic Resonance Spectroscopy; Micrococcaceae; Molecular Structure; Nocardia; Penicillium; Polyketides | 2020 |
Design and synthesis of amphiphilic 2-hydroxybenzylphosphonium salts with antimicrobial and antitumor dual action.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Arthrodermataceae; Bacillus cereus; Candida albicans; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Organophosphorus Compounds; Staphylococcus aureus | 2020 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Synthesis and bioassay of a new class of heterocycles pyrrolyl oxadiazoles/thiadiazoles/triazoles.
Topics: Anti-Infective Agents; Antineoplastic Agents; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Thiadiazoles; Triazoles | 2009 |
Synthesis and anti-microbial screening of some Schiff bases of 3-amino-6,8-dibromo-2-phenylquinazolin-4(3H)-ones.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Quinazolinones; Schiff Bases; Structure-Activity Relationship | 2009 |
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.
Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Carrageenan; Drug Discovery; Edema; Female; Lipid Peroxidation; Male; Mice; Microwaves; Nucleosides; Quinolines; Rats | 2009 |
Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Candida albicans; Microbial Sensitivity Tests; Pyridones; Pyrones; Quantitative Structure-Activity Relationship; Staphylococcus aureus | 2009 |
Antimicrobial ambiguine isonitriles from the cyanobacterium Fischerella ambigua.
Topics: Anti-Bacterial Agents; Bacillus anthracis; Cyanobacteria; Indole Alkaloids; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular | 2009 |
Regioselective synthesis and biological evaluation of bis(indolyl)methane derivatized 1,4-disubstituted 1,2,3-bistriazoles as anti-infective agents.
Topics: Anti-Infective Agents; Methane; Microbial Sensitivity Tests; Stereoisomerism; Triazoles | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Bacteria; Cell Proliferation; Drug Screening Assays, Antitumor; Erythrocytes; Hemolysis; Heterocyclic Compounds; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Rats; Stereoisomerism; Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agents.
Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Cell Line, Tumor; Fungi; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Triazines | 2011 |
Isoxazoles incorporated N-substituted decahydroquinolines: a precursor to the next generation antimicrobial drug.
Topics: Anti-Infective Agents; Bacteria; Fungi; Isoxazoles; Nitrogen; Quinolines | 2012 |
Synthesis and biological evaluation of some thiazolidinones as antimicrobial agents.
Topics: Anti-Infective Agents; Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazolidines | 2012 |
Regioselective synthesis and antimicrobial activities of some novel aryloxyacetic acid derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Fungi; Hydrazones; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Sulfones | 2012 |
Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity.
Topics: Anti-Infective Agents; Bacteria; Chemistry Techniques, Synthetic; Fungi; Indoles; Microbial Sensitivity Tests; Oxindoles | 2012 |
Design and synthesis of new 4-pyrazolin-3-yl-1,2,3-triazoles and 1,2,3-triazol-4-yl-pyrazolin-1-ylthiazoles as potential antimicrobial agents.
Topics: Anti-Infective Agents; Chemistry Techniques, Synthetic; Drug Design; Microbial Sensitivity Tests; Thiazoles; Triazoles | 2012 |
Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents.
Topics: Antifungal Agents; Antitubercular Agents; Bacteria; Benzothiazoles; Chemistry Techniques, Synthetic; Fungi; Microbial Sensitivity Tests; Mycobacterium tuberculosis | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Thiourea derivatives incorporating a hippuric acid moiety: synthesis and evaluation of antibacterial and antifungal activities.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; Fungi; Hippurates; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiourea | 2013 |
3-Anhydro-6-hydroxy-ophiobolin A, a new sesterterpene inhibiting the growth of methicillin-resistant Staphylococcus aureus and inducing the cell death by apoptosis on K562, from the phytopathogenic fungus Bipolaris oryzae.
Topics: Apoptosis; Cell Death; Drug Screening Assays, Antitumor; Flow Cytometry; Hep G2 Cells; Humans; K562 Cells; Methicillin-Resistant Staphylococcus aureus; Oryza; Sesterterpenes; Structure-Activity Relationship | 2013 |
Synthesis of thiosemicarbazones derived from N-(4-hippuric acid)thiosemicarbazide and different carbonyl compounds as antimicrobial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; Fungi; Hippurates; Microbial Sensitivity Tests; Molecular Structure; Semicarbazides; Structure-Activity Relationship; Thiosemicarbazones | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Streptomyces; Vero Cells | 2013 |
Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole.
Topics: Anti-Bacterial Agents; Antifungal Agents; Benzimidazoles; Benzothiazoles; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Penicillium chrysogenum; Staphylococcus aureus; Structure-Activity Relationship | 2014 |
Synthesis, antimicrobial activity and advances in structure-activity relationships (SARs) of novel tri-substituted thiazole derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus flavus; Aspergillus niger; Bacteria; Chemistry Techniques, Synthetic; Drug Design; Models, Molecular; Molecular Conformation; Static Electricity; Structure-Activity Relationship; Thiazoles | 2016 |
Infectious keratitis in leprosy.
Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Female; Humans; Ketoconazole; Leprosy, Lepromatous; Leprosy, Tuberculoid; Male; Middle Aged; Risk Factors; Visual Acuity | 1999 |
Pharmacokinetic interaction of ketoconazole and itraconazole with ciprofloxacin.
Topics: Animals; Anti-Infective Agents; Antifungal Agents; Area Under Curve; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Interactions; Half-Life; Itraconazole; Ketoconazole; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Time Factors | 2008 |
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software.
Topics: Ciprofloxacin; Clarithromycin; Computer Simulation; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Fluconazole; Humans; Itraconazole; Ketoconazole; Models, Biological; Paroxetine; Quinidine; Rifampin; Software | 2018 |
Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro.
Topics: Animals; Ciprofloxacin; Clotrimazole; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ketoconazole; Liver; Microsomes, Liver; Oncorhynchus mykiss; Sulfamethoxazole | 2022 |