ketoconazole and carbon tetrachloride

ketoconazole has been researched along with carbon tetrachloride in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Alvarez, E; Colombato, LO; Guma, C; Lami, G; Miyashiro, R; Olmos, M1
Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW1
Kang, TW; Kim, JH; Lim, JP1
Huang, K; Peng, C; Zhou, Y; Zhou, Z1
Ahmed, M; Akhtar, U; Ali, G; Shehzad, U; Tayyeb, A1

Other Studies

10 other study(ies) available for ketoconazole and carbon tetrachloride

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Hepatic lesions induced by drugs. Report of 26 cases].
    Acta gastroenterologica Latinoamericana, 1987, Volume: 17, Issue:2

    Topics: Adult; Aged; Biopsy; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Estrogens; Female; Humans; Indomethacin; Ketoconazole; Liver; Male; Methyldopa; Middle Aged; Penicillins

1987
Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition.
    Molecular and cellular biochemistry, 1993, May-26, Volume: 122, Issue:2

    Topics: Aminopyrine; Animals; Carbon Tetrachloride; Catalase; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Ketoconazole; Lipid Peroxidation; Male; Proadifen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase

1993
Effect of biphenyl dimethyl dicarboxylate on the humoral immunosuppression by ketoconazole in mice.
    Archives of pharmacal research, 1999, Volume: 22, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Carbon Tetrachloride; Dioxoles; Immunosuppressive Agents; Ketoconazole; Liver; Male; Mice; Mice, Inbred ICR; Organ Size

1999
Ketoconazole pretreatment ameliorates carbon tetrachloride-induced acute liver injury in rats by suppressing inflammation and oxidative stress.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytokines; Glutathione; Ketoconazole; Liver; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley

2019
Hepatoprotective effect of ketoconazole in chronic liver injury model.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:3

    Topics: Actins; Animals; Carbon Tetrachloride; Cell Death; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation; Hepatocytes; Ketoconazole; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Liver Function Tests; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Protective Agents

2019