ketoconazole and calcitriol

ketoconazole has been researched along with calcitriol in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (11.48)	18.7374
1990's	23 (37.70)	18.2507
2000's	18 (29.51)	29.6817
2010's	13 (21.31)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bernstein, G; Chuang, SS; Dolan, PM; Kahraman, M; Kensler, TW; Korczak, B; Peleg, S; Posner, GH; Saha, U; Sinishtaj, S	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aboraia, AS; Brancale, A; DeLuca, HF; Ferla, S; Ochalek, JT; Pepper, CJ; Simons, C; Zhu, J	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Carazo, A; Drechslerová, M; Hrušková, ZR; Hyrsova, L; Kuneš, J; Nova, A; Pavek, P; Pour, M; Smutny, T; Špulák, M	1
Berkoben, M; Brown, AJ; Ritter, CS; Slatopolsky, E	1
Breitman, TR; Takahashi, N	1
Bayley, D; Cooper, RG; Denton, J; Freemont, AJ; Hayes, ME; Mawer, EB; Palit, J; Still, P	1
Birkenhäger, JC; Bos, MP; Pols, HA; Schilte, JP; van Leeuwen, JP	1
Bayley, D; Hayes, ME; Mawer, EB	1
Bia, MJ; Insogna, K	1
Adams, JS; Beeker, TG; Clemens, TL; Hongo, T	1
Brown, A; Delmez, J; Dusso, AS; Finch, J; Ritter, C; Schreiner, G; Slatopolsky, E	1
Cerletty, JM; Eil, C; Elliott, W; Glass, AR; Gray, RW; Lemann, J	1
Adams, JS; Diz, MM; Endres, DB; Sharma, OP	1
Horst, RL; Reinhardt, TA	1
Birkenhager, JC; Pols, HA; Schilte, HP; Visser, TJ	1
Birkenhäger, JC; Pols, HA; Schilte, JP; Visser, TJ	1
Amado, JA; Freijanes, J; González Macías, J; Otero, M; Riancho, JA	1
Eil, C; Glass, AR	2
Henry, HL	1
Boass, A; Toverud, SU	1
Feuillan, PP	1
Aukrust, P; Frøland, SS; Haug, C; Müller, F	1
Benítez, J; Esbrit, P; Muncio, MJ; Traba, ML	1
Davies, M; Hayes, ME; Heys, SE; Mawer, EB; Smith, GN; Stewart, MF; White, A	1
Adams, JS; Arbelle, JE; Clemens, TL; Gray, RW; Horiuchi, N; Ren, SY; Shany, S	1
Baroncelli, GI; Bertelloni, S; Di Nero, G; Saggese, G	1
Bouillon, R; Marcelis, S; Tan, BK; Verstuyf, A; Zhao, J	1
Phillips, SB; Potts, CE; Shelanski, MV	1
Duell, EA; Kang, S; Li, XY; Voorhees, JJ	1
Gardner, JP; Kheir, A; Studzinski, GP; Uskokovic, MR; Wang, X	1
Bland, R; Hewison, M; Hughes, SV; Stewart, PM; Walker, EA	1
Brown, G; Campbell, MJ; Drayson, MT; Durham, J; Reddy, GS; Siu-Caldera, ML; Wallington, L	1
Jones, G; Kamao, M; Kremer, R; Makin, HL; Masuda, S; Okano, T; Rhim, J; Schroeder, NJ	1
Lehmann, B; Meurer, M; Pietzsch, J; Rudolph, T	1
Baillie, MT; Gibbs, MA; Kunze, KL; Shen, DD; Thummel, KE	1
Bouillon, R; Carlberg, C; De Clercq, P; Quack, M; Van Camp, M; Van Etten, E; Vandewalle, M; Verlinden, L; Verstuyf, A	1
Feldman, D; Peehl, DM; Seto, E	1
Knuschke, P; Lehmann, B; Meurer, M	1
Bastien, Y; Diamandis, EP; Ho, J; Hudson, TJ; Lin, R; Nagai, Y; Petrecca, K; Sladek, R; Sotiropoulou, G; White, JH	1
Feldman, D; Hsu, JY; Peehl, DM; Seto, E	1
Dressler, S; Knuschke, P; Lehmann, B; Meurer, M; Sauter, W	1
Deng, CH; Huang, X; Krochmal, L; Lenn, J; Tanojo, H	1
Davis, CL; Hashizume, T; Kalhorn, TF; Nelson, WL; Sakaki, T; Schuetz, EG; Shuhart, MC; Thummel, KE; Watkins, PB; Xu, Y	1
Campbell, MJ; Simons, C; Yee, SW	1
Azuma, J; Hou, XL; Kinoshita, N; Komatsu, K; Qiu, F; Takahashi, K; Tanaka, K	1
Hashimoto, K; Iwasaki, Y; Kambayashi, M; Kawahara, M; Nigawara, T; Nishiyama, M; Sakaguchi, K; Suda, T; Taguchi, T; Tsugita, M	1
Dupont, I; Jassogne, C; Larondelle, Y; McAlister, D; Muller, M; Pussemier, L; Ribonnet, L; Schneider, YJ; Scippo, ML; Sergent, T; van der Heiden, E	1
Engler, KL; Johnson, CS; Kong, RX; Ma, Y; Muindi, JR; Trump, DL; Yu, WD	1
Allen, JD; Kota, BP; Roufogalis, BD	1
Chelminski, PR; Foreman, JW; Harris, PC; Horst, RL; Kumar, R; Milliner, DS; Singh, RJ; Tebben, PJ; Wu, Y	1
Carpenter, TO	1
Baurska, H; Kutner, A; Kłopot, A; Marchwicka, A; Marcinkowska, E	1
Blackburn, J; Blom, A; Ishizawa, M; Lancaster, ST; Makishima, M; Mansell, JP	1
Boding, L; Bonefeld, CM; Geisler, C; Kongsbak, M; Lauritsen, JP; Levring, TB; Schjerling, P; von Essen, MR; Woetmann, A; Ødum, N	1
Anderson, PH; Callen, DF; Dhatrak, DJ; Gill, PG; Morris, HA; Pishas, KI; Sheng, L; Turner, AG	1

Reviews

4 review(s) available for ketoconazole and calcitriol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Ketoconazole decreases the serum ionized calcium and 1,25-dihydroxyvitamin D levels in tuberculosis-associated hypercalcemia. American journal of diseases of children (1960), 1993, Volume: 147, Issue:3 Topics: 25-Hydroxyvitamin D 2; Adolescent; Calcitriol; Calcium; Child; Creatinine; Humans; Hydrocortisone; Hypercalcemia; Ketoconazole; Male; Parathyroid Hormone; Phosphorus; Radiography; Thyroid Function Tests; Tuberculosis, Pulmonary	1993
Rationale for combination ketoconazole/ vitamin D treatment of prostate cancer. Urology, 2001, Volume: 58, Issue:2 Suppl 1 Topics: Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Drug Synergism; Humans; Ketoconazole; Male; Prostatic Neoplasms; Vitamin D	2001
A novel foam vehicle for delivery of topical corticosteroids. Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:1 Suppl 1 Topics: Administration, Cutaneous; Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Betamethasone; Body Water; Calcitriol; Clindamycin; Clobetasol; Dermatologic Agents; Dosage Forms; Hot Temperature; Humans; Ketoconazole; Ointments; Pharmaceutical Vehicles; Skin; Skin Absorption	2005

Trials

1 trial(s) available for ketoconazole and calcitriol

Article	Year
Evaluation of cutaneous reactivity to recently marketed dermatologic products. International journal of dermatology, 1996, Volume: 35, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Allergens; Antifungal Agents; Calcitriol; Clobetasol; Dermatitis, Irritant; Dermatologic Agents; Double-Blind Method; Doxepin; Drug Prescriptions; Female; Humans; Hypersensitivity; Imidazoles; Irritants; Ketoconazole; Male; Metronidazole; Middle Aged; Mupirocin; Naphthalenes; Patch Tests; Pharmaceutical Vehicles; Placebos; Risk Factors; Skin; Terbinafine	1996

Article

Year

Evaluation of cutaneous reactivity to recently marketed dermatologic products.

International journal of dermatology, 1996, Volume: 35, Issue:2

Topics: Adult; Aged; Aged, 80 and over; Allergens; Antifungal Agents; Calcitriol; Clobetasol; Dermatitis, Irritant; Dermatologic Agents; Double-Blind Method; Doxepin; Drug Prescriptions; Female; Humans; Hypersensitivity; Imidazoles; Irritants; Ketoconazole; Male; Metronidazole; Middle Aged; Mupirocin; Naphthalenes; Patch Tests; Pharmaceutical Vehicles; Placebos; Risk Factors; Skin; Terbinafine

1996

Other Studies

56 other study(ies) available for ketoconazole and calcitriol

Article	Year
Potent, selective and low-calcemic inhibitors of CYP24 hydroxylase: 24-sulfoximine analogues of the hormone 1alpha,25-dihydroxyvitamin D(3). Journal of medicinal chemistry, 2004, Dec-30, Volume: 47, Issue:27 Topics: Animals; Calcitriol; Calcium; Cytochrome P-450 Enzyme Inhibitors; Male; Rats; Rats, Inbred F344; Steroid Hydroxylases; Structure-Activity Relationship; Sulfones; Vitamin D3 24-Hydroxylase	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation. Journal of medicinal chemistry, 2014, Sep-25, Volume: 57, Issue:18 Topics: Antineoplastic Agents; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Cytochrome P-450 Enzyme Inhibitors; Heme; Humans; Imidazoles; Inhibitory Concentration 50; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Molecular; Sequence Homology, Amino Acid; Structure-Activity Relationship; Vitamin D3 24-Hydroxylase	2014
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists. Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10 Topics: Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hep G2 Cells; Hepatocytes; Humans; Models, Molecular; Molecular Structure; Quinazolines; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship	2016
Binding and metabolism of 1,25-dihydroxyvitamin D3 in cultured bovine parathyroid cells. Endocrinology, 1992, Volume: 130, Issue:1 Topics: Animals; Calcitriol; Cattle; Cells, Cultured; Ketoconazole; Parathyroid Glands; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger	1992
Covalent modification of proteins by ligands of steroid hormone receptors. Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-15, Volume: 89, Issue:22 Topics: Calcitriol; Dinoprostone; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Estradiol; Humans; Iodine Radioisotopes; Ketoconazole; Kinetics; Leukemia, Promyelocytic, Acute; Ligands; Molecular Weight; Neoplasm Proteins; Progesterone; Protein Binding; Receptors, Steroid; Thyroxine; Triiodothyronine; Tritium; Tumor Cells, Cultured	1992
Differential metabolism of 25-hydroxyvitamin D3 by cultured synovial fluid macrophages and fibroblast-like cells from patients with arthritis. Annals of the rheumatic diseases, 1992, Volume: 51, Issue:2 Topics: 24,25-Dihydroxyvitamin D 3; Adult; Aged; Arthritis; Calcifediol; Calcitriol; Cells, Cultured; Female; Fibroblasts; Humans; Ketoconazole; Lipopolysaccharides; Macrophages; Male; Middle Aged; Synovial Fluid	1992
The effects of MC903 on 1,25-(OH)2D3 receptor binding, 24-hydroxylase activity and in vitro bone resorption. Bone and mineral, 1991, Volume: 14, Issue:2 Topics: Animals; Binding Sites; Bone Resorption; Calcitriol; Calcium; Cell Division; Cell Line; Cytochrome P-450 Enzyme System; Enzyme Induction; Ketoconazole; Mice; Osteoblasts; Oxidation-Reduction; Receptors, Calcitriol; Receptors, Steroid; Steroid Hydroxylases; Up-Regulation; Vitamin D3 24-Hydroxylase	1991
Studies on an adherent variant of the human promyelomonocytic HL60 leukaemia cell line that constitutively expresses 25-hydroxyvitamin D3-24-hydroxylase activity which is inhibited by 1 alpha,25-dihydroxyvitamin D3. Journal of molecular endocrinology, 1991, Volume: 7, Issue:3 Topics: Calcitriol; Cell Adhesion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Leukemia, Promyelocytic, Acute; Steroid Hydroxylases; Tumor Cells, Cultured; Vitamin D3 24-Hydroxylase	1991
Treatment of sarcoidosis-associated hypercalcemia with ketoconazole. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:6 Topics: Calcitriol; Calcium; Humans; Hypercalcemia; Ketoconazole; Kidney Failure, Chronic; Male; Middle Aged; Prednisone; Sarcoidosis	1991
Constitutive expression of a vitamin D 1-hydroxylase in a myelomonocytic cell line: a model for studying 1,25-dihydroxyvitamin D production in vitro. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1990, Volume: 5, Issue:12 Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Calcitriol; Cell Line, Transformed; Chickens; Free Radical Scavengers; Free Radicals; Ketoconazole; Kinetics; Macrophages; Models, Biological; Monocytes; Phenylenediamines; Receptors, Calcitriol; Receptors, Steroid	1990
Extrarenal production of calcitriol in normal and uremic humans. The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1 Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Calcitriol; Cytochrome P-450 Enzyme Inhibitors; Humans; Ketoconazole; Kidney Failure, Chronic; Macrophages; Parathyroid Hormone; Peptide Fragments; Teriparatide; Uremia	1991
Ketoconazole reduces elevated serum levels of 1,25-dihydroxyvitamin D in hypercalcemic sarcoidosis. Journal of endocrinological investigation, 1990, Volume: 13, Issue:5 Topics: Adult; Calcifediol; Calcitriol; Calcium; Creatinine; Cyclic AMP; Humans; Hypercalcemia; Ketoconazole; Kidney; Male; Parathyroid Hormone; Sarcoidosis	1990
Ketoconazole decreases the serum 1,25-dihydroxyvitamin D and calcium concentration in sarcoidosis-associated hypercalcemia. The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:4 Topics: Adult; Calcitriol; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Hypercalcemia; Ketoconazole; Kinetics; Lung Diseases; Macrophage Activation; Macrophages; Male; Pulmonary Alveoli; Sarcoidosis	1990
Ketoconazole inhibits self-induced metabolism of 1,25-dihydroxyvitamin D3 and amplifies 1,25-dihydroxyvitamin D3 receptor up-regulation in rat osteosarcoma cells. Archives of biochemistry and biophysics, 1989, Aug-01, Volume: 272, Issue:2 Topics: Animals; Calcitriol; Ketoconazole; Osteosarcoma; Rats; Receptors, Calcitriol; Receptors, Steroid; Tumor Cells, Cultured	1989
Effect of ketoconazole on metabolism and binding of 1,25-dihydroxyvitamin D-3 by intact rat osteogenic sarcoma cells. Biochimica et biophysica acta, 1987, Nov-12, Volume: 931, Issue:2 Topics: Animals; Biotransformation; Calcitriol; Cell Line; Ketoconazole; Kinetics; Osteosarcoma; Rats; Receptors, Calcitriol; Receptors, Steroid	1987
Evidence that the self-induced metabolism of 1,25-dihydroxyvitamin D-3 limits the homologous up-regulation of its receptor in rat osteosarcoma cells. Biochimica et biophysica acta, 1988, Jun-30, Volume: 970, Issue:2 Topics: Animals; Calcitriol; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Ketoconazole; Kinetics; Osteosarcoma; Rats; Receptors, Calcitriol; Receptors, Steroid; Tumor Cells, Cultured	1988
Ketoconazole and vitamin D metabolism in hyperparathyroidism. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:1 Topics: Adult; Aged; Calcitriol; Calcium; Humans; Hyperparathyroidism; Ketoconazole; Middle Aged; Vitamin D	1989
Ketoconazole-induced reduction in serum 1,25-dihydroxyvitamin D and total serum calcium in hypercalcemic patients. The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Calcitriol; Calcium; Female; Humans; Hypercalcemia; Ketoconazole; Male; Middle Aged	1988
Ketoconazole-induced reduction in serum 1,25-dihydroxyvitamin D. The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:3 Topics: Adolescent; Adult; Calcitriol; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Ketoconazole; Male	1986
Effect of ketoconazole and miconazole on 25-hydroxyvitamin D3 metabolism by cultured chick kidney cells. Journal of steroid biochemistry, 1985, Volume: 23, Issue:6A Topics: Animals; Calcifediol; Calcitriol; Cells, Cultured; Chickens; Ketoconazole; Kidney; Miconazole	1985
Suppression of circulating calcitriol and duodenal active Ca transport by ketoconazole in pregnant rats. The American journal of physiology, 1995, Volume: 269, Issue:5 Pt 1 Topics: Animals; Biological Transport, Active; Calcitriol; Calcium; Dose-Response Relationship, Drug; Duodenum; Female; Ketoconazole; Lactation; Osmolar Concentration; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley	1995
McCune-Albright syndrome. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Adolescent; Calcitriol; Diagnosis, Differential; Female; Fibrous Dysplasia, Polyostotic; Humans; Ketoconazole; Leuprolide; Male; Medroxyprogesterone Acetate; Octreotide; Ovariectomy; Propylthiouracil; Puberty, Precocious; Spironolactone; Testolactone; Thyroid Diseases	1994
Subnormal serum concentration of 1,25-vitamin D in human immunodeficiency virus infection: correlation with degree of immune deficiency and survival. The Journal of infectious diseases, 1994, Volume: 169, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Biopterins; Calcitriol; CD4-Positive T-Lymphocytes; Follow-Up Studies; HIV Infections; Humans; Ketoconazole; Leukocyte Count; Neopterin; Nutrition Disorders; Proportional Hazards Models; Survival Analysis; T-Lymphocytes, Regulatory	1994
Role of parathormone-related protein and 1,25-dihydroxyvitamin D in the hypercalcemia of Walker 256 tumor-host rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1994, Volume: 26, Issue:6 Topics: Animals; Calcitriol; Carcinoma 256, Walker; Female; Hypercalcemia; Ketoconazole; Parathyroid Hormone-Related Protein; Proteins; Rats; Rats, Wistar	1994
Constitutive synthesis of 1,25-dihydroxyvitamin D3 by a human small cell lung cancer cell line. The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:2 Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Calcifediol; Calcitriol; Calcium; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Humans; Ketoconazole; Lung Neoplasms; Mass Spectrometry; Parathyroid Hormone; Receptors, Calcitriol; Tumor Cells, Cultured	1994
Regulated production and intracrine action of 1,25-dihydroxyvitamin D3 in the chick myelomonocytic cell line HD-11. Endocrinology, 1994, Volume: 134, Issue:6 Topics: Animals; Calcifediol; Calcitriol; Calcium; Cell Division; Cell Line, Transformed; Chickens; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Genes, myc; Granulocytes; Hydroxylation; Insulin-Like Growth Factor I; Interferon-gamma; Ketoconazole; Lipopolysaccharides; Monocytes; Phosphates; Vitamin K	1994
Enhancement of antiproliferative activity of 1alpha,25-dihydroxyvitamin D3 (analogs) by cytochrome P450 enzyme inhibitors is compound- and cell-type specific. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 57, Issue:3-4 Topics: Calcitriol; Cell Division; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Tumor Cells, Cultured	1996
The retinoid X receptor agonist 9-cis-retinoic acid and the 24-hydroxylase inhibitor ketoconazole increase activity of 1,25-dihydroxyvitamin D3 in human skin in vivo. The Journal of investigative dermatology, 1997, Volume: 108, Issue:4 Topics: Adult; Alitretinoin; Calcitriol; Cytochrome P-450 Enzyme System; Drug Synergism; Gene Expression; Humans; Ketoconazole; Receptors, Retinoic Acid; Retinoid X Receptors; Skin; Steroid Hydroxylases; Transcription Factors; Transcription, Genetic; Tretinoin; Vitamin D3 24-Hydroxylase	1997
Synergistic induction of HL60 cell differentiation by ketoconazole and 1-desoxy analogues of vitamin D3. Journal of the National Cancer Institute, 1997, Aug-20, Volume: 89, Issue:16 Topics: Antineoplastic Agents; Biomarkers, Tumor; Calcium; Calcium Channels; CD11 Antigens; Cell Differentiation; Cell Division; Drug Synergism; HL-60 Cells; Humans; Ketoconazole; Leukemia, Myeloid; Lipopolysaccharide Receptors; Monocytes; Vitamin D	1997
Constitutive expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium. Endocrinology, 1999, Volume: 140, Issue:5 Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Blotting, Western; Calcifediol; Calcitriol; Calcium; Cell Line; Cell Line, Transformed; Chromatography, High Pressure Liquid; Colforsin; Enzyme Inhibitors; Gene Expression; Humans; Ketoconazole; Kidney Tubules, Proximal; Kinetics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin D	1999
Metabolism of 1alpha,25(OH)2D3 and its 20-epi analog integrates clonal expansion, maturation and apoptosis during HL-60 cell differentiation. Molecular and cellular endocrinology, 1999, Mar-25, Volume: 149, Issue:1-2 Topics: Apoptosis; Calcitriol; Cell Differentiation; Cell Division; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; HL-60 Cells; Humans; Ketoconazole; Models, Biological; Steroid Hydroxylases; Vitamin D3 24-Hydroxylase	1999
Characterization of 3-epi-1alpha,25-dihydroxyvitamin D3 involved in 1alpha,25-dihydroxyvitamin D3 metabolic pathway in cultured cell lines. Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:2 Topics: Animals; Antifungal Agents; Calcitriol; Cell Division; Cell Line; Chromatography, High Pressure Liquid; HL-60 Cells; Humans; Ketoconazole; Magnetic Resonance Spectroscopy; Organ Specificity; Rats; Receptors, Calcitriol; Spectrophotometry, Ultraviolet; Stereoisomerism; Swine; Vitamin D-Binding Protein	2000
Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 in human skin equivalents. Experimental dermatology, 2000, Volume: 9, Issue:2 Topics: Cells, Cultured; Cholecalciferol; Enzyme Inhibitors; Humans; Hydroxylation; Keratinocytes; Ketoconazole; Kinetics; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Serum Albumin, Bovine; Time Factors; Vitamin D	2000
Persistent inhibition of CYP3A4 by ketoconazole in modified Caco-2 cells. Pharmaceutical research, 2000, Volume: 17, Issue:3 Topics: Antifungal Agents; Caco-2 Cells; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; GABA Modulators; Humans; Hydroxylation; Ketoconazole; Midazolam; Mixed Function Oxygenases; Vitamin D	2000
Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:4 Topics: Adenocarcinoma; Alkynes; Animals; Breast Neoplasms; Calcitriol; Cell Division; Chlorocebus aethiops; Cholecalciferol; COS Cells; Dimerization; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Ketoconazole; Macromolecular Substances; Mice; Protein Conformation; Protein Multimerization; Receptors, Calcitriol; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured	2001
A novel pathway for hormonally active calcitriol. Hormone research, 2000, Volume: 54, Issue:5-6 Topics: Calcitriol; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Humans; Ketoconazole; Ultraviolet Rays	2000
Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation. Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:6 Topics: Biomarkers, Tumor; Calcitriol; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Division; Cholecalciferol; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immune System; Ketoconazole; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured	2002
Preclinical activity of ketoconazole in combination with calcitriol or the vitamin D analogue EB 1089 in prostate cancer cells. The Journal of urology, 2002, Volume: 168, Issue:4 Pt 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cell Division; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Ketoconazole; Male; Prostatic Neoplasms; Steroid Hydroxylases; Tumor Cells, Cultured; Tumor Stem Cell Assay; Vitamin D3 24-Hydroxylase	2002
Demonstration of UVB-induced synthesis of 1 alpha,25-dihydroxyvitamin D3 (calcitriol) in human skin by microdialysis. Archives of dermatological research, 2003, Volume: 295, Issue:1 Topics: Abdomen; Administration, Topical; Calcitriol; Dehydrocholesterols; Epidermis; Humans; Ketoconazole; Microdialysis; Photolysis; Reference Values; Skin; Ultraviolet Rays	2003
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia. Molecular pharmacology, 2006, Volume: 69, Issue:1 Topics: Base Sequence; Caco-2 Cells; Calbindins; Calcitriol; Catalysis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Intestine, Small; Ketoconazole; Kinetics; Liver; Midazolam; Osteomalacia; Recombinant Proteins; S100 Calcium Binding Protein G; Troleandomycin	2006
Inhibition of Vitamin D3 metabolism enhances VDR signalling in androgen-independent prostate cancer cells. The Journal of steroid biochemistry and molecular biology, 2006, Volume: 98, Issue:4-5 Topics: Androgens; Animals; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Ketoconazole; Kidney; Male; Mitochondria; Neoplasms, Hormone-Dependent; Nuclear Proteins; Prostatic Neoplasms; Rats; Rats, Wistar; Receptors, Calcitriol; Signal Transduction; Steroid Hydroxylases; Tumor Cells, Cultured; Vitamin D; Vitamin D3 24-Hydroxylase	2006
Possible inhibitory mechanism of Curcuma drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells. International journal of pharmaceutics, 2007, Jun-07, Volume: 337, Issue:1-2 Topics: Caco-2 Cells; Calcitriol; Cell Survival; Curcuma; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Herb-Drug Interactions; Humans; Hydroxylation; Inhibitory Concentration 50; Intestinal Mucosa; Ketoconazole; Nifedipine; Oxidation-Reduction; Plant Extracts; Rhizome; Rifampin; RNA, Messenger; Testosterone	2007
Predominant role of 25OHD in the negative regulation of PTH expression: clinical relevance for hypovitaminosis D. Life sciences, 2008, Mar-26, Volume: 82, Issue:13-14 Topics: Animals; Base Sequence; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Feedback, Physiological; Genetic Vectors; Humans; Hyperparathyroidism, Secondary; Ketoconazole; Luciferases; Molecular Sequence Data; Parathyroid Glands; Parathyroid Hormone; Plasmids; Promoter Regions, Genetic; Rats; Reverse Transcriptase Polymerase Chain Reaction; Steroid Hydroxylases; Transcription, Genetic; Vitamin D; Vitamin D Deficiency	2008
CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides. Toxicology letters, 2009, Feb-10, Volume: 184, Issue:3 Topics: Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Calcitriol; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Food Contamination; Fungicides, Industrial; Glutathione Transferase; Humans; Imidazoles; Intestinal Mucosa; Ketoconazole; Kinetics; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; Spectrophotometry, Ultraviolet; Triazoles	2009
CYP24A1 inhibition enhances the antitumor activity of calcitriol. Endocrinology, 2010, Volume: 151, Issue:9 Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Calcitriol; Calcium; Caspase 3; Cell Line, Tumor; Cell Proliferation; Dexamethasone; Drug Synergism; Glucocorticoids; Humans; Ketoconazole; Kidney; Male; Mice; Mice, Inbred C3H; Mice, Nude; Prostatic Neoplasms; Steroid Hydroxylases; Time Factors; Vitamin D3 24-Hydroxylase; Vitamins; Xenograft Model Antitumor Assays	2010
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance. Basic & clinical pharmacology & toxicology, 2011, Volume: 109, Issue:2 Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcitriol; Cell Line, Tumor; Colchicine; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; Ketoconazole; Receptors, Calcitriol; Rhodamine 123	2011
Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:3 Topics: 14-alpha Demethylase Inhibitors; Adult; Calcitriol; Genotype; Humans; Hypercalcemia; Hypercalciuria; Ketoconazole; Male; Mutation; Steroid Hydroxylases; Syndrome; Treatment Outcome; Vitamin D3 24-Hydroxylase	2012
Take another CYP: confirming a novel mechanism for "idiopathic" hypercalcemia. The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:3 Topics: 14-alpha Demethylase Inhibitors; Calcitriol; Humans; Hypercalcemia; Hypercalciuria; Ketoconazole; Male; Steroid Hydroxylases; Vitamin D3 24-Hydroxylase	2012
Studies on the mechanisms of superagonistic pro-differentiating activities of side-chain modified analogs of vitamin D2. Oncology reports, 2012, Volume: 28, Issue:3 Topics: Antineoplastic Agents; Calcitriol; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Ergocalciferols; Gene Expression; HL-60 Cells; Humans; Ketoconazole; Kinetics; Lipopolysaccharide Receptors; Mitochondria; Protein Transport; Receptors, Calcitriol; Retinoid X Receptors; Steroid Hydroxylases; Up-Regulation; Vitamin D3 24-Hydroxylase	2012
24,25-Dihydroxyvitamin D3 cooperates with a stable, fluoromethylene LPA receptor agonist to secure human (MG63) osteoblast maturation. Steroids, 2014, Volume: 83 Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Calcitriol; Cell Differentiation; Fluorescent Dyes; Humans; Ketoconazole; Mitogens; Organophosphonates; Osteoblasts; Osteocalcin; Receptors, Calcitriol; Receptors, Lysophosphatidic Acid; Stereoisomerism; Transcription, Genetic; Tretinoin	2014
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PloS one, 2014, Volume: 9, Issue:5 Topics: Antifungal Agents; Calcitriol; CD4 Antigens; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytochrome P-450 CYP3A Inhibitors; Fatty Acids, Unsaturated; Humans; Ketoconazole; Lymphocyte Activation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Transport; Proteolysis; Receptors, Calcitriol; Up-Regulation	2014
Identification of vitamin D The Journal of steroid biochemistry and molecular biology, 2016, Volume: 164 Topics: Antineoplastic Agents; Breast; Breast Neoplasms; Calcitriol; Cell Adhesion; Cell Line, Tumor; Cholecalciferol; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Ketoconazole; MCF-7 Cells; Membrane Proteins; Neoplasm Recurrence, Local; Peptide Elongation Factors; Ribonucleoprotein, U5 Small Nuclear; Sequence Analysis, RNA; Serpins; Signal Transduction; Transcription, Genetic; Up-Regulation; Vitamin D3 24-Hydroxylase	2016