ketoconazole has been researched along with buthionine sulfoximine in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Evans, WK; Stewart, DJ | 1 |
| Chen, X; Jin, H; Shen, S; Zheng, J; Zhong, D | 1 |
| Jiang, H; Ma, L; Shen, Q; Tian, Y; Wang, L; Yu, L; Zeng, S; Zhou, H; Zhou, Q; Zuo, M | 1 |
| Ding, L; Li, X; Ma, S; Pan, H; Shi, F; Zhao, P | 1 |
| Gao, H; Li, W; Lin, D; Meng, D; Peng, Y; Smith, CV; Xu, Y; Zheng, J | 1 |
| Fukami, T; Iida, A; Nakajima, M; Sasaki, E; Tsuneyama, K; Yano, A; Yokoi, T | 1 |
| Gao, H; Guo, X; Lin, D; Peng, Y; Wang, K; Zheng, J | 1 |
1 review(s) available for ketoconazole and buthionine sulfoximine
| Article | Year |
|---|---|
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Topics: Adult; Amphotericin B; Animals; Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Child; Clinical Trials as Topic; Dipyridamole; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Methionine Sulfoximine; Mice; Neoplasms; Nitroimidazoles; Xanthines | 1989 |
1 trial(s) available for ketoconazole and buthionine sulfoximine
| Article | Year |
|---|---|
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Topics: Adult; Amphotericin B; Animals; Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Calcium Channel Blockers; Calmodulin; Cardiotonic Agents; Child; Clinical Trials as Topic; Dipyridamole; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ketoconazole; Male; Methionine Sulfoximine; Mice; Neoplasms; Nitroimidazoles; Xanthines | 1989 |
8 other study(ies) available for ketoconazole and buthionine sulfoximine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzylisoquinolines; Blotting, Western; Bronchi; Buthionine Sulfoximine; Caspase 3; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochromes c; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Glutathione; Humans; In Situ Nick-End Labeling; Ketoconazole; Lung; Male; Mice; Tetrahydroisoquinolines | 2012 |
Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Benzylisoquinolines; Buthionine Sulfoximine; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Glutathione; Hep G2 Cells; Humans; Indolequinones; Ketoconazole; Kinetics; Madin Darby Canine Kidney Cells; Microsomes, Liver; Troleandomycin | 2014 |
Cytotoxicity of luteolin in primary rat hepatocytes: the role of CYP3A-mediated ortho-benzoquinone metabolite formation and glutathione depletion.
Topics: Animals; Apoptosis; Benzoquinones; Buthionine Sulfoximine; Cell Line; Chromatography, Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Glutathione; Hepatocytes; Ketoconazole; Luteolin; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2015 |
Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Furans; Glutathione; Heterocyclic Compounds, 4 or More Rings; Ketoconazole; Liver; Male; Mice; Structure-Activity Relationship | 2016 |
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.
Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Antifungal Agents; Buthionine Sulfoximine; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Enzyme Induction; Enzyme Inhibitors; Glutathione; Hydroxylation; Ketoconazole; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred F344; Troleandomycin | 2015 |
Lysine- and cysteine-based protein adductions derived from toxic metabolites of 8-epidiosbulbin E acetate.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Dioscorea; Diterpenes; In Vitro Techniques; Ketoconazole; Lysine; Male; Medicine, East Asian Traditional; Mice; Microsomes, Liver; Oxidation-Reduction; Proteins | 2016 |