ketoconazole and beta-naphthoflavone

ketoconazole has been researched along with beta-naphthoflavone in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL1
Atodiresei, I; Fiebig, HH; Fleischhauer, J; Gerhäuser, C; Kehraus, S; Klimo, K; König, GM; Krick, A; Maier, A; Nieger, M; Raabe, G1
Aeri, K; Chang, M; Kim, HJ; Koh, JS; Lee, SH1
Klahr, S; Reyes, AA1
Frosini, M; Fusi, F; Pessina, F; Sgaragli, GP; Tipton, KF; Valoti, M1
Kagayama, A; Mitani, Y; Niwa, T; Shiraga, T; Terakawa, M; Tokuma, Y1
de Graaf, IA; de Jager, MH; Groothuis, GM; Meijer, DK; van de Kerkhof, EG1
Liu, ZH; Zeng, S1
Huang, SD; Jiang, HD; Li, LP; Sun, DL; Sun, SY; Zeng, S; Zhao, M1

Other Studies

9 other study(ies) available for ketoconazole and beta-naphthoflavone

ArticleYear
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Development; Enzyme Inhibitors; Freund's Adjuvant; Humans; Lipopolysaccharides; Male; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Structure-Activity Relationship

2021
Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis.
    Journal of natural products, 2007, Volume: 70, Issue:3

    Topics: Anticarcinogenic Agents; Aromatase Inhibitors; Ascomycota; Crystallography, X-Ray; Inhibitory Concentration 50; Marine Biology; Molecular Conformation; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Xanthones

2007
Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities.
    Bioorganic & medicinal chemistry letters, 2012, May-01, Volume: 22, Issue:9

    Topics: Alkyl and Aryl Transferases; Animals; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Imidazoles; Isoenzymes; Microsomes, Liver; Piperazines

2012
Cytochrome P-450 pathway in renal function of normal rats and rats with bilateral ureteral obstruction.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 201, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blood Pressure; Cytochrome P-450 Enzyme System; Enzyme Activation; Female; Glomerular Filtration Rate; Hemodynamics; Ketoconazole; Kidney; Kidney Cortex; Methylcholanthrene; Microsomes; Rats; Rats, Sprague-Dawley; Ureteral Obstruction

1992
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl.
    European journal of pharmacology, 2000, Mar-17, Volume: 391, Issue:3

    Topics: Animals; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfiram; Enzyme Induction; Enzyme Inhibitors; Ethanol; Fomepizole; In Vitro Techniques; Isoenzymes; Ketoconazole; Mice; Mice, Inbred C57BL; Microsomes, Liver; Monoamine Oxidase Inhibitors; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Pyrazoles; Selegiline

2000
Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cell Line; Chromatography, High Pressure Liquid; Clofibrate; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Female; Humans; Imidazoles; Ketoconazole; Kinetics; Male; Microsomes; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Quinidine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sex Factors; Stereoisomerism

2000
Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:11

    Topics: Animals; beta-Naphthoflavone; Colon; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Glucuronides; Intestine, Small; Ketoconazole; Male; Models, Animal; Rats; Rats, Wistar; Testosterone; Time Factors; Tissue Culture Techniques; Umbelliferones

2005
Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes.
    Toxicology letters, 2009, Jun-22, Volume: 187, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fomepizole; Hepatocytes; Humans; Isoenzymes; Ketoconazole; Liver; Male; Microsomes, Liver; Pyrazoles; Quinine; Rats; Rats, Sprague-Dawley; Salicylates; Sulfaphenazole

2009
Stereoselective metabolism of tetrahydropalmatine enantiomers in rat liver microsomes.
    Chirality, 2012, Volume: 24, Issue:5

    Topics: Animals; Berberine Alkaloids; beta-Naphthoflavone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes; Dexamethasone; Dogs; Fluvoxamine; Haplorhini; Ketoconazole; Male; Membrane Proteins; Metabolic Clearance Rate; Mice; Mice, Inbred ICR; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substrate Specificity

2012