Compounds > ketoconazole

ketoconazole and axitinib

ketoconazole has been researched along with axitinib in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garrett, M; Hee, B; Klamerus, KJ; Mount, J; Pithavala, YK; Rahavendran, SV; Sarapa, N; Selaru, P; Tong, W1
Houk, BE; Pithavala, YK; Ruiz-Garcia, A; Sarapa, N; Toh, M; Tortorici, MA1

Trials

2 trial(s) available for ketoconazole and axitinib

ArticleYear
Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Administration, Oral; Adult; Angiogenesis Inhibitors; Area Under Curve; Axitinib; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Genotype; Humans; Imidazoles; Indazoles; Ketoconazole; Male; Middle Aged; Phenotype; Single-Blind Method

2012
Effect of axitinib on the QT interval in healthy volunteers.
    Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:3

    Topics: Adult; Axitinib; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Electrocardiography; Female; Heart Rate; Humans; Imidazoles; Indazoles; Ketoconazole; Male; Models, Biological; Protein Kinase Inhibitors; Single-Blind Method

2015