ketoconazole and atazanavir sulfate

ketoconazole has been researched along with atazanavir sulfate in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abel, S; Muirhead, GJ; Ridgway, CE; Russell, D; Taylor-Worth, RJ1
Collins, C; Dickins, M; Hyland, R; Jones, B; Jones, H1
Li, F; Lu, J; Ma, X; Wang, L1
Chowan, GS; Desikan, S; Gautam, SS; Mandlekar, S; Padmanabhan, S; Saxena, A; Shah, D1

Trials

1 trial(s) available for ketoconazole and atazanavir sulfate

ArticleYear
Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Anti-HIV Agents; Antifungal Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; Cyclohexanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Ketoconazole; Male; Maraviroc; Middle Aged; Oligopeptides; Pyridines; Saquinavir; Statistics as Topic; Triazoles

2008

Other Studies

3 other study(ies) available for ketoconazole and atazanavir sulfate

ArticleYear
Maraviroc: in vitro assessment of drug-drug interaction potential.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:4

    Topics: Area Under Curve; Atazanavir Sulfate; Cyclohexanes; Cytochrome P-450 CYP3A; Drug Interactions; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Ketoconazole; Liver; Male; Maraviroc; Microsomes, Liver; Oligopeptides; Predictive Value of Tests; Pyridines; Ritonavir; Saquinavir; Triazoles

2008
CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Aldehydes; Animals; Atazanavir Sulfate; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Feces; HIV Protease Inhibitors; Humans; Hydrazines; Ketoconazole; Metabolomics; Mice; Microsomes, Liver; Oligopeptides; Pyridines; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Prediction of pH dependent absorption using in vitro, in silico, and in vivo rat models: Early liability assessment during lead optimization.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Aug-30, Volume: 76

    Topics: Administration, Oral; Animals; Atazanavir Sulfate; Chemistry, Pharmaceutical; Computer Simulation; Drug Discovery; Gastric Absorption; Gastric Acid; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Ketoconazole; Male; Models, Biological; Rats, Wistar; Solubility; Species Specificity

2015