ketoconazole has been researched along with arachidonic acid in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 13 (61.90) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
| Douglas, JG; Goldthwait, DA; Hopfer, U; Madhun, ZT; McKay, D | 1 |
| Bonventre, JV; Sellmayer, A; Uedelhoven, WM; Weber, PC | 1 |
| Adler, H; Coons, MS; Damiani, P; Horovitz, J; Marini, CP; Tachmes, L; Woloszyn, TT | 1 |
| Badr, KF; Harris, RC; Munger, KA; Takahashi, K | 1 |
| Beetens, JR; Coene, MC; De Clerck, F; Loots, W; Somers, Y | 1 |
| Capdevila, J; Falck, JR; Gil, L; Marnett, LJ; Mason, JI; Orellana, M; Yadagiri, P | 1 |
| Fuller, BL; Tolman, EL | 1 |
| Jackson, P; McManus, M; Serhan, C; Strange, K | 1 |
| Nakamura, S; Nomura, T; Ryoyama, K | 1 |
| Gustafsson, JA; Hamberg, M; Mode, A; Tollet, P | 1 |
| Hallahan, DE; Kufe, DW; Virudachalam, S; Weichselbaum, RR | 1 |
| Bayer, AL; Koop, DR; Laethem, CL; Simonson, MS; Thibonnier, M | 1 |
| Badr, KF; Capdevila, JH; Harris, RC; Jacobson, HR; Karara, A; Makita, K; Munger, KA; Takahashi, K | 1 |
| Kasiske, BL; Keane, WF; Kim, Y; O'Donnell, MP | 1 |
| Forn, J; García-Rafanell, J; Merlos, M; Vericat, ML | 1 |
| Akard, L; Boswell, HS; Carlo-Stella, C; Dugan, M; Garau, D; Regazzi, E; Rizzo, MT; Rizzoli, V | 1 |
| Alexander, LD; Cui, XL; Douglas, JG; Falck, JR | 1 |
| Flordellis, C; Karkoulias, G; Lymperopoulos, A; Mastrogianni, O; Paris, H | 1 |
| Funae, Y; Imaoka, S; Oguro, A; Sakamoto, K | 1 |
| Guardiola, J; Li, H; Lin, S; Moldoveanu, B; Xu, L; Yu, J | 1 |
21 other study(ies) available for ketoconazole and arachidonic acid
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channels; Cells, Cultured; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytosol; Ketoconazole; Kidney Tubules, Proximal; Male; Oxygenases; Rabbits; Signal Transduction | 1991 |
Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Blotting, Northern; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Epidermal Growth Factor; Gas Chromatography-Mass Spectrometry; Glomerular Mesangium; Indomethacin; Ketoconazole; Male; Masoprocol; Pyridines; Rats; Rats, Inbred WKY; RNA, Messenger; Tetradecanoylphorbol Acetate | 1991 |
Role of arachidonic acid metabolites in oleic acid induced pulmonary injury in a canine model. Effect of ketoconazole (thromboxane synthetase inhibitor).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dogs; Hemodynamics; Ketoconazole; Lung; Lung Diseases; Oleic Acid; Oleic Acids; Thromboxane B2 | 1991 |
Mediation of renal vascular effects of epidermal growth factor by arachidonate metabolites.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dinoprost; Epidermal Growth Factor; Fatty Acids, Unsaturated; Glomerular Filtration Rate; Hydrazines; Ibuprofen; Ketoconazole; Kidney; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Regional Blood Flow | 1990 |
Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bronchi; Catechols; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ketoconazole; Leukotriene B4; Lipoxygenase Inhibitors; Male; Masoprocol; Neutrophils; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains; Reticulocytes; SRS-A | 1986 |
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Indomethacin; Ketoconazole; Male; Masoprocol; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains | 1988 |
Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell-Free System; Clotrimazole; Female; Guinea Pigs; Humans; Imidazoles; Ketoconazole; Lung; Miconazole; Thromboxane B2; Thromboxanes | 1983 |
Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion.
Topics: Animals; Anions; Arachidonic Acid; Brain Neoplasms; Chromatography, High Pressure Liquid; Eicosanoids; Glioma; Inositol; Ion Channels; Ketoconazole; Leukotriene Antagonists; Osmosis; Prostaglandin-Endoperoxide Synthases; Rats; Tumor Cells, Cultured | 1994 |
Inhibition of macrophage nitric oxide production by arachidonate-cascade inhibitors.
Topics: Acetophenones; Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Caffeic Acids; Dexamethasone; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione Transferase; Indomethacin; Ketoconazole; Lipoxygenase; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Phospholipases A; Phospholipases A2; Sodium Nitrite; Umbelliferones | 1993 |
Growth hormone signaling leading to CYP2C12 gene expression in rat hepatocytes involves phospholipase A2.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Diglycerides; Enzyme Activation; Gene Expression Regulation; Growth Hormone; Insulin-Like Growth Factor I; Ketoconazole; Lactams, Macrocyclic; Liver; Phospholipases A; Phospholipases A2; Phospholipids; Phosphorylation; Proadifen; Protein-Tyrosine Kinases; Quinacrine; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Verapamil | 1995 |
Ketoconazole attenuates radiation-induction of tumor necrosis factor.
Topics: Arachidonic Acid; Blotting, Northern; Cyclooxygenase Inhibitors; DNA, Complementary; Gene Expression; Gene Expression Regulation, Leukemic; Genes, jun; Humans; Ketoconazole; Leukemia, Myeloid; Lipoxygenase Inhibitors; Phospholipases A; Phospholipases A2; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Role of eicosanoids in vasopressin-induced calcium mobilization in A7r5 vascular smooth muscle cells.
Topics: Animals; Arachidonic Acid; Arginine Vasopressin; Biological Transport; Calcium; Cell Line; Eicosanoids; Electrophysiology; Indomethacin; Intracellular Membranes; Ketoconazole; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular | 1993 |
Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration.
Topics: Alkaline Phosphatase; Animals; Arachidonic Acid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glomerular Filtration Rate; Ketoconazole; Kidney; Male; Microsomes; Nephrectomy; Oxygenases; Rats; Rats, Wistar; Renal Circulation; Sodium-Potassium-Exchanging ATPase | 1993 |
Oxidative modification of low-density lipoproteins by mesangial cells.
Topics: Antioxidants; Arachidonic Acid; Butylated Hydroxytoluene; Catalase; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; DNA Replication; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Hydroxyurea; Indomethacin; Ketoconazole; Lipoproteins, LDL; Lipoxygenase Inhibitors; Masoprocol; Oxidation-Reduction; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 1993 |
Topical anti-inflammatory properties of flutrimazole, a new imidazole antifungal agent.
Topics: Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Antifungal Agents; Arachidonic Acid; Carrageenan; Clotrimazole; Cyclooxygenase Inhibitors; Diclofenac; Edema; Granulocytes; Humans; Ketoconazole; Leukotriene B4; Male; Mice; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Induction of apoptosis by arachidonic acid in chronic myeloid leukemia cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Animals; Antioxidants; Apoptosis; Arachidonic Acid; Bone Marrow Cells; Caffeic Acids; Cell Division; Colony-Forming Units Assay; Erythroid Precursor Cells; Female; Hematopoietic Stem Cells; Humans; Indomethacin; Ketoconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Masoprocol; Mice; Middle Aged; Tumor Cells, Cultured | 1999 |
Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antifungal Agents; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carbon Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Fatty Acids; JNK Mitogen-Activated Protein Kinases; Ketoconazole; Kidney Tubules, Proximal; Male; MAP Kinase Kinase 3; MAP Kinase Kinase 6; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Rabbits | 2001 |
alpha(2)-Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR.
Topics: Adrenergic alpha-Agonists; Animals; Antifungal Agents; Arachidonic Acid; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Epinephrine; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Ketoconazole; MAP Kinase Signaling System; Matrix Metalloproteinases; Oxidoreductases; PC12 Cells; Phosphatidylinositol 3-Kinases; Protein Isoforms; Proto-Oncogene Proteins c-akt; Quinacrine; Rats; Receptor, trkA; Receptors, Adrenergic, alpha-2; src-Family Kinases; Transcriptional Activation | 2006 |
Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells.
Topics: 14-alpha Demethylase Inhibitors; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Cell Cycle; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chromones; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Eicosanoids; Enzyme Inhibitors; Flavonoids; Gene Expression; Genes, Reporter; Humans; Isoquinolines; Ketoconazole; Luciferases; Mitogen-Activated Protein Kinases; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Quinidine; RNA; Sulfonamides; Transfection | 2011 |
Arachidonic acid products in airway nociceptor activation during acute lung injury.
Topics: Acute Lung Injury; Animals; Arachidonic Acid; Indomethacin; Ketoconazole; Male; Nociceptors; Oleic Acid; Rabbits; Thromboxane-A Synthase | 2011 |