ketoconazole has been researched along with allopurinol in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 8 (25.81) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 14 (45.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Kittakoop, P; Mahidol, C; Prachya, S; Ruchirawat, S; Tianpanich, K; Wiyakrutta, S | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| de Pauw, BE; Haanen, C; Stalpers, LJ; Verhagen, C | 1 |
| Berman, JD; Gallalee, JV | 1 |
| Durack, DT; Smego, RA | 1 |
| Mukherjee, A; Ramesh, V | 1 |
| Chandra, J; Patwari, AK | 1 |
| Baum, KF; Berens, RL | 1 |
| al-Eisa, A; Alfurayh, O; Damanhouri, G; Dammas, S; Halim, MA; Kalin, ME | 1 |
| Cook, GC | 1 |
| Jha, S; Jha, TK; Singh, IJ; Singh, NK | 1 |
| Balaña-Fouce, R; Cubría, JC; Ordóñez, D; Reguera, RM | 1 |
| Alsina, J; Bover, J; Gil-Vernet, S; Grinyó, JM; Hueso, M; Rufí, G; Serón, D | 1 |
| Bakirtaç, A; Kara, C; Kuyucu, N; Teziç, T | 1 |
| Kohno, M; Muraoka, W; Nakashima, T; Niwano, Y; Oda, T; Sato, E | 1 |
4 review(s) available for ketoconazole and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Post-kala-azar dermal leishmaniasis.
Topics: Allopurinol; Amphotericin B; Antimony Sodium Gluconate; Humans; Incidence; Ketoconazole; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral | 1995 |
Diagnosis and treatment of kala-azar.
Topics: Allopurinol; Amphotericin B; Antimony Sodium Gluconate; Child; Combined Modality Therapy; Humans; Ketoconazole; Leishmaniasis, Visceral; Pentamidine; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity; Splenectomy | 1994 |
The pharmacology of leishmaniasis.
Topics: Allopurinol; Amphotericin B; Animals; Antiprotozoal Agents; Drug Design; Humans; Itraconazole; Ketoconazole; Leishmania; Leishmaniasis; Paromomycin; World Health Organization | 1998 |
27 other study(ies) available for ketoconazole and allopurinol
| Article | Year |
|---|---|
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.
Topics: Antineoplastic Agents; Antioxidants; Aromatase Inhibitors; Benzofurans; Biphenyl Compounds; Colletotrichum; Drug Screening Assays, Antitumor; Free Radical Scavengers; Hep G2 Cells; HL-60 Cells; Humans; Isocoumarins; Lactones; Molecular Structure; Picrates; Piper; Structure-Activity Relationship; Thailand | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Drug-induced skin reactions in patients with acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Allopurinol; Cephalosporins; Drug Combinations; Drug Eruptions; Female; Humans; Ketoconazole; Leukemia; Male; Miconazole; Penicillins; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1987 |
In vitro antileishmanial activity of inhibitors of steroid biosynthesis and combinations of antileishmanial agents.
Topics: Allopurinol; Allylamine; Amines; Antifungal Agents; Antimony Sodium Gluconate; Antiprotozoal Agents; Drug Combinations; Humans; Ketoconazole; Leishmania; Naphthalenes; Ribonucleosides; Terbinafine | 1987 |
In vitro susceptibility testing of Naegleria fowleri to ketoconazole, BAYn7133, and allopurinol riboside.
Topics: Allopurinol; Amoeba; Amphotericin B; Animals; Antiprotozoal Agents; Ketoconazole; Microbial Sensitivity Tests; Ribonucleosides; Triazoles | 1984 |
Successful treatment of cutaneous leishmaniasis with allopurinol after failure of treatment with ketoconazole.
Topics: Adult; Allopurinol; Animals; Belize; Drug Resistance; Forestry; Humans; Ketoconazole; Leishmania mexicana; Leishmaniasis, Cutaneous; Male; Occupational Diseases; United States | 1994 |
Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in a renal transplant recipient after the occurrence of pancreatitis due to stibogluconate.
Topics: Adult; Allopurinol; Antimony Sodium Gluconate; Drug Therapy, Combination; Female; Humans; Ketoconazole; Kidney Transplantation; Leishmaniasis, Visceral; Pancreatitis | 1993 |
Leishmaniasis: some recent developments in chemotherapy.
Topics: Allopurinol; Amphotericin B; Antiprotozoal Agents; Humans; Ketoconazole; Leishmaniasis; Paromomycin | 1993 |
Combination therapy in Kala-azar.
Topics: Adult; Allopurinol; Antimony Sodium Gluconate; Antiprotozoal Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ketoconazole; Leishmaniasis, Visceral; Levamisole; Male | 1995 |
The renal transplant patient with visceral leishmaniasis who could not tolerate meglumine antimoniate-cure with ketoconazole and allopurinol.
Topics: Aged; Allopurinol; Antiprotozoal Agents; Drug Therapy, Combination; Humans; Ketoconazole; Kidney Transplantation; Leishmaniasis, Visceral; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds | 1999 |
Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate.
Topics: Acute Disease; Allopurinol; Antiprotozoal Agents; Child, Preschool; Humans; Ketoconazole; Leishmaniasis, Visceral; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Pancreatitis | 2001 |
Inhibitory or scavenging action of ketoconazole and ciclopiroxolamine against reactive oxygen species released by primed inflammatory cells.
Topics: Animals; Antifungal Agents; Ciclopirox; Dermatitis, Atopic; Drug Combinations; Female; Ketoconazole; Mice; Pyridones; Reactive Oxygen Species; Treatment Outcome; Xanthine Oxidase | 2007 |